SRSF3 and NXF1

Number of citations of the paper that reports this interaction (PMID 17036044)
47

Data Source:
HPRD (in vitro)

		SRSF3	NXF1
Gene Name		serine/arginine-rich splicing factor 3	nuclear RNA export factor 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Transcription Export Complex Nuclear Pore Nucleoplasm Cytosol Nuclear Speck Nuclear Inclusion Body
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding MRNA Binding Nucleocytoplasmic Transporter Activity Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing	MRNA Export From Nucleus Gene Expression Viral Process Poly(A)+ MRNA Export From Nucleus
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	Transport of Mature mRNA Derived from an Intronless Transcript Processing of Capped Intron-Containing Pre-mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA derived from an Intron-Containing Transcript Transport of Mature mRNAs Derived from Intronless Transcripts Transport of the SLBP independent Mature mRNA Transport of Mature Transcript to Cytoplasm
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: APP CHD1 CLK1 EXOSC6 GEMIN2 HNRNPK IL7R NXF1 PCBP1 PCBP2 PRPF38A RBM7 RBMY1A1 SCAF11 SREK1 SRPK1 SRPK2 SRSF2 TRA2B YWHAB YWHAG YWHAQ	51 interactors: ALYREF CSNK2A1 DHX9 DVL3 EIF4A3 ELAVL4 ESRRA GFAP HNRNPUL1 IMPA1 IPO11 IPO4 KCTD5 KRT40 LDOC1 MAGOH MAP1A MAP1B MID2 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A SGTA SH2D3A SRSF1 SRSF3 SRSF7 STRAP THOC5 TIFA TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN4 UPF3A XIST ZBED2
Entrez ID		6428	10482
HPRD ID		04530	04035
Ensembl ID			ENSG00000162231
Uniprot IDs		B2R6F3 P84103	Q59E96 Q9UBU9
PDB IDs		2I2Y 2I38	1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Nitrogen Compound Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrion Organization Spliceosomal Complex Assembly Regulation Of Mitochondrion Organization Immune Response Positive Regulation Of Viral Genome Replication Ribonucleoprotein Complex Biogenesis Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Intrinsic Apoptotic Signaling Pathway Innate Immune Response Positive Regulation Of Apoptotic Signaling Pathway Regulation Of RNA Metabolic Process Negative Regulation Of Viral Genome Replication Cellular Metabolic Process Nuclear Speck Organization Positive Regulation Of Intracellular Transport Immunoglobulin Production Cellular Process MRNA Export From Nucleus Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Intracellular Transport Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Interleukin-7-mediated Signaling Pathway RNA Export From Nucleus Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Positive Regulation Of Cell Death	RNA Transport RNA Localization MRNA Transport Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Nuclear Export MRNA Export From Nucleus Cytoplasmic Transport Intracellular Transport MRNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Establishment Of Localization In Cell RNA Processing Gene Expression Cellular Localization Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing Viral Process RNA 3'-end Processing Mitotic Nuclear Envelope Disassembly DNA-templated Transcription, Termination Viral Life Cycle RNA Metabolic Process Nuclear Envelope Disassembly Regulation Of MRNA Splicing, Via Spliceosome Nuclear Import Nuclear Envelope Organization Glucose Transport Nucleobase-containing Compound Metabolic Process Hexose Transport Regulation Of MRNA Processing Viral Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Glucose Transport Regulation Of RNA Splicing Transport Cellular Nitrogen Compound Metabolic Process Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Intracellular Transport Of Virus Regulation Of Alternative MRNA Splicing, Via Spliceosome Protein Import Nitrogen Compound Metabolic Process Protein Localization To Nucleus
Tagcloud ?		1alpha activate alter atpase cadherin caffeine cardiac conferred depletion detailed digoxin g2 glycosides governing hela hypoxia isoform mesenchymal modulate modulated na p53alpha p53beta pumping repositioning snail splicing switch transition	betaretrovirus cte gag gammaretroviral gammaretrovirus gammaretroviruses isogenic lentiviruses license mason mlv mpmv nxt pfizer pol polyprotein polyribosomes polysome polysomes pr65gag quantitated retrovirus retroviruses shuttling srp20 synergized synthesize unspliced xmrv
Tagcloud (Difference) ?		1alpha activate alter atpase cadherin caffeine cardiac conferred depletion detailed digoxin g2 glycosides governing hela hypoxia isoform mesenchymal modulate modulated na p53alpha p53beta pumping repositioning snail splicing switch transition	betaretrovirus cte gag gammaretroviral gammaretrovirus gammaretroviruses isogenic lentiviruses license mason mlv mpmv nxt pfizer pol polyprotein polyribosomes polysome polysomes pr65gag quantitated retrovirus retroviruses shuttling srp20 synergized synthesize unspliced xmrv
Tagcloud (Intersection) ?