NXF1 and MAGOH

Number of citations of the paper that reports this interaction (PubMedID 11707413)
53

Data Source:
HPRD (in vivo, in vitro)

		NXF1	MAGOH
Description		nuclear RNA export factor 1	mago homolog, exon junction complex subunit
Image
GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck Nuclear RNA Export Factor Complex Nuclear Inclusion Body	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome Exon-exon Junction Subcomplex Mago-y14
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus Protein Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing MRNA Export From Nucleus Regulation Of Translation RNA Splicing Regulation Of MRNA Processing MRNA Transport Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Pathways		Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		138 interacting genes: ALDOA ALYREF APOBEC3C AUNIP BACH2 BECN1 BICD2 BIN3 BIRC2 BLMH BTBD18 C10orf55 C1orf35 CAMK2G CCDC120 CCDC196 CCDC197 CCDC7 CDYL2 CEBPA CEP55 CLK2 CLK3 CPSF7 CSNK2A1 CTTN DDX50 DHX9 DMRTB1 DVL3 ECSIT EIF4A3 ELAVL4 ESRRA EXOSC8 FAM9A FTO GFAP GOLGA6L9 GPBP1 GTPBP2 HNRNPUL1 HOMEZ HOXA1 HSF2BP IMPA1 IPO11 IPO4 ISY1-RAB43 KATNBL1 KCTD5 KCTD7 KIF24 KRT31 KRT40 LCE3E LDOC1 LUZP4 MAGOH MAP1A MAP1B MBD3L1 MID2 MRNIP MTUS2 NKAPD1 NME1 NME4 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 PEG10 PIH1D2 PPP1R12C PRKAR1B PRPH PRR3 PRRC2B PURB QKI RAD51 RAE1 RALYL RAN RANBP2 RBFOX2 RBM15B RBM22 RBMX RBPMS REDIC1 RPRD1A SGTA SH2D3A SH3GLB2 SLAIN1 SNRPA SNW1 SPATC1L SRPK2 SRSF1 SRSF3 SRSF4 SRSF7 SRSF8 STRAP SYCP3 TBC1D14 TCP10L TEX9 TFIP11 THOC5 TIFA TNFAIP1 TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN1 UBQLN4 UPF3A VAPA VIM VPS28 WEE2-AS1 XIST ZBED2 ZC3HAV1 ZNF250 ZNF343 ZNF438	22 interacting genes: ALYREF CEP70 CORO1A CPSF7 DPH2 DPPA4 EIF4A3 FXR1 GOLGA2 IPO13 MAP1B NXF1 PPP1R16B PTBP2 RBM8A TADA2A TFIP11 UPF3B XIST YWHAQ ZKSCAN8 ZRANB1
Entrez ID		10482	4116
HPRD ID		04035	04005
Ensembl ID		ENSG00000162231	ENSG00000162385
Uniprot IDs		Q59E96 Q9UBU9	P61326
PDB IDs		1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7 4WYK 6E5U	1P27 2HYI 2J0Q 2J0S 2XB2 3EX7 7A5P 7W59 7W5A 7W5B 7ZNJ 8C6J 8I0W 9FMD
Enriched GO Terms of Interacting Partners?		MRNA Transport RNA Transport Nucleobase-containing Compound Transport RNA Binding RNA Export From Nucleus MRNA Binding Nuclear Transport Nucleocytoplasmic Transport Nuclear Export Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing MRNA Metabolic Process RNA Splicing MRNA Processing Regulation Of MRNA Metabolic Process MRNA Export From Nucleus Nucleic Acid Binding RNA Processing Nucleus Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Metabolic Process RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Intracellular Transport Nucleic Acid Metabolic Process Nuclear RNA Export Factor Complex Nucleoplasm Positive Regulation Of RNA Splicing Identical Protein Binding Import Into Nucleus Protein Binding Cellular Localization Nuclear Localization Sequence Binding Nuclear Pore Spliceosomal Complex Catalytic Step 2 Spliceosome Protein Import Into Nucleus Nucleobase-containing Compound Metabolic Process Nuclear Speck Positive Regulation Of MRNA Splicing, Via Spliceosome Establishment Of Localization In Cell Protein Localization To Nucleus Exon-exon Junction Complex Establishment Of Protein Localization To Organelle Poly(A)+ MRNA Export From Nucleus Protein Localization To Organelle Nuclear Envelope Intracellular Protein Transport Negative Regulation Of MRNA Metabolic Process	MRNA Binding MRNA Transport Exon-exon Junction Complex Nucleic Acid Binding RNA Transport Nucleobase-containing Compound Transport MRNA Export From Nucleus Spliceosomal Complex RNA Export From Nucleus Catalytic Step 2 Spliceosome MRNA Metabolic Process Nuclear Transport Nucleocytoplasmic Transport Nuclear Speck Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Processing Nuclear Export Cellular Localization RNA Binding Intracellular Transport Neuronal Cell Body RNA Splicing U2-type Catalytic Step 1 Spliceosome Transcription Export Complex Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nucleus Nuclear-transcribed MRNA Catabolic Process Establishment Of Localization In Cell MRNA Catabolic Process RNA Processing Regulation Of MRNA Metabolic Process Induction Of Synaptic Plasticity By Chemical Substance Ribonucleoprotein Complex Binding Positive Regulation Of Translation Negative Regulation Of Selenocysteine Incorporation Cellular Response To Selenite Ion RNA Metabolic Process Regulation Of RNA Splicing Regulation Of Translation RNA Catabolic Process Organelle Assembly MRNA Splicing, Via Spliceosome 2-(3-amino-3-carboxypropyl)histidine Synthase Complex 2-(3-amino-3-carboxypropyl)histidine Synthase Activity Uropod Organization Spliceosomal Complex Disassembly RNA Splicing, Via Transesterification Reactions Dendrite
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