SRSF3 and PCBP1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SRSF3	PCBP1
Gene Name		serine/arginine-rich splicing factor 3	poly(rC) binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleoplasm Cytoplasm Membrane Ribonucleoprotein Complex Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	Single-stranded DNA Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: APP CHD1 CLK1 EXOSC6 GEMIN2 HNRNPK IL7R NXF1 PCBP1 PCBP2 PRPF38A RBM7 RBMY1A1 SCAF11 SREK1 SRPK1 SRPK2 SRSF2 TRA2B YWHAB YWHAG YWHAQ	36 interactors: ANP32A APP CAV3 CELF2 CELF3 ERG EWSR1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL LMNA MATR3 NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBM11 RBM42 SNRPA SRSF3 TCERG1 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830
Entrez ID		6428	5093
HPRD ID		04530	03128
Ensembl ID			ENSG00000169564
Uniprot IDs		B2R6F3 P84103	Q15365 Q53SS8
PDB IDs		2I2Y 2I38	1WVN 1ZTG 3VKE
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Nitrogen Compound Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrion Organization Spliceosomal Complex Assembly Regulation Of Mitochondrion Organization Immune Response Positive Regulation Of Viral Genome Replication Ribonucleoprotein Complex Biogenesis Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Intrinsic Apoptotic Signaling Pathway Innate Immune Response Positive Regulation Of Apoptotic Signaling Pathway Regulation Of RNA Metabolic Process Negative Regulation Of Viral Genome Replication Cellular Metabolic Process Nuclear Speck Organization Positive Regulation Of Intracellular Transport Immunoglobulin Production Cellular Process MRNA Export From Nucleus Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Intracellular Transport Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Interleukin-7-mediated Signaling Pathway RNA Export From Nucleus Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Positive Regulation Of Cell Death	MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Cell Aging Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Macromolecule Biosynthetic Process Negative Regulation Of Potassium Ion Transmembrane Transport MRNA 3'-end Processing RNA Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Ventricular Cardiac Muscle Cell Action Potential RNA 3'-end Processing Nucleocytoplasmic Transport Nuclear Transport Negative Regulation Of Potassium Ion Transport Regulation Of Membrane Repolarization Regulation Of Translation Cellular Process Cardiac Muscle Cell Action Potential Involved In Contraction Biosynthetic Process MRNA Polyadenylation Positive Regulation Of RNA Splicing Cardiac Muscle Cell Action Potential RNA Polyadenylation
Tagcloud ?		1alpha activate alter atpase cadherin caffeine cardiac conferred depletion detailed digoxin g2 glycosides governing hela hypoxia isoform mesenchymal modulate modulated na p53alpha p53beta pumping repositioning snail splicing switch transition	atypical au element encoding eta half knockdown markedly owing pigmentosum polh poly prone rc responsive rich stability sufficient suppressor tls transcript translesion tumour uncovered upon utr variant xeroderma xpv
Tagcloud (Difference) ?		1alpha activate alter atpase cadherin caffeine cardiac conferred depletion detailed digoxin g2 glycosides governing hela hypoxia isoform mesenchymal modulate modulated na p53alpha p53beta pumping repositioning snail splicing switch transition	atypical au element encoding eta half knockdown markedly owing pigmentosum polh poly prone rc responsive rich stability sufficient suppressor tls transcript translesion tumour uncovered upon utr variant xeroderma xpv
Tagcloud (Intersection) ?