NXF1 and IPO11

Number of citations of the paper that reports this interaction (PMID 22658674)
106

Data Source:
BioGRID (affinity chromatography technology, pull down)

		NXF1	IPO11
Gene Name		nuclear RNA export factor 1	importin 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex Nuclear Pore Nucleoplasm Cytosol Nuclear Speck Nuclear Inclusion Body	Nucleus Cytoplasm
	Molecular Function	Nucleotide Binding MRNA Binding Nucleocytoplasmic Transporter Activity Protein Binding Poly(A) RNA Binding	Ran GTPase Binding Protein Transporter Activity
	Biological Process	MRNA Export From Nucleus Gene Expression Viral Process Poly(A)+ MRNA Export From Nucleus	Ribosomal Protein Import Into Nucleus
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript Processing of Capped Intron-Containing Pre-mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA derived from an Intron-Containing Transcript Transport of Mature mRNAs Derived from Intronless Transcripts Transport of the SLBP independent Mature mRNA Transport of Mature Transcript to Cytoplasm
Drugs
Diseases
GWAS			Alcohol and nictotine co-dependence ( 23216389)
Protein-Protein Interactions		51 interactors: ALYREF CSNK2A1 DHX9 DVL3 EIF4A3 ELAVL4 ESRRA GFAP HNRNPUL1 IMPA1 IPO11 IPO4 KCTD5 KRT40 LDOC1 MAGOH MAP1A MAP1B MID2 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A SGTA SH2D3A SRSF1 SRSF3 SRSF7 STRAP THOC5 TIFA TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN4 UPF3A XIST ZBED2	11 interactors: C1orf94 EIF4A2 KEAP1 NXF1 PLCD4 RAN RPL12 TRAF2 UBE2E1 UBE2E2 UBE2E3
Entrez ID		10482	51194
HPRD ID		04035	10003
Ensembl ID		ENSG00000162231	ENSG00000086200
Uniprot IDs		Q59E96 Q9UBU9	Q9UI26
PDB IDs		1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7
Enriched GO Terms of Interacting Partners?		RNA Transport RNA Localization MRNA Transport Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Nuclear Export MRNA Export From Nucleus Cytoplasmic Transport Intracellular Transport MRNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Establishment Of Localization In Cell RNA Processing Gene Expression Cellular Localization Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing Viral Process RNA 3'-end Processing Mitotic Nuclear Envelope Disassembly DNA-templated Transcription, Termination Viral Life Cycle RNA Metabolic Process Nuclear Envelope Disassembly Regulation Of MRNA Splicing, Via Spliceosome Nuclear Import Nuclear Envelope Organization Glucose Transport Nucleobase-containing Compound Metabolic Process Hexose Transport Regulation Of MRNA Processing Viral Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Glucose Transport Regulation Of RNA Splicing Transport Cellular Nitrogen Compound Metabolic Process Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Intracellular Transport Of Virus Regulation Of Alternative MRNA Splicing, Via Spliceosome Protein Import Nitrogen Compound Metabolic Process Protein Localization To Nucleus	Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation ISG15-protein Conjugation Catabolic Process Protein K11-linked Ubiquitination Viral Process Cellular Response To Cytokine Stimulus Response To Cytokine Positive Regulation Of Proteolysis Cellular Macromolecule Catabolic Process Positive Regulation Of Protein Binding Negative Regulation Of RNA-directed RNA Polymerase Activity Cellular Protein Metabolic Process Cytokine-mediated Signaling Pathway Nuclear Export Positive Regulation Of Binding Ribosomal Small Subunit Export From Nucleus Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Ubiquitin-independent Protein Catabolic Process Regulation Of Protein Binding Nuclear-transcribed MRNA Catabolic Process Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process MRNA Catabolic Process Protein Metabolic Process Regulation Of Proteolysis Cytoplasmic Transport RNA Catabolic Process Negative Regulation Of Glial Cell Apoptotic Process Viral Life Cycle Cellular Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Ribosomal Large Subunit Export From Nucleus Histone H2B Ubiquitination Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Ribosomal Subunit Export From Nucleus Poly(A)+ MRNA Export From Nucleus Regulation Of Cell Cycle Phase Transition Translational Initiation Positive Regulation Of Protein Homodimerization Activity Metabolic Process Cellular Response To Nitric Oxide Nucleocytoplasmic Transport Proteasomal Protein Catabolic Process Regulation Of Binding
Tagcloud ?		betaretrovirus cte gag gammaretroviral gammaretrovirus gammaretroviruses isogenic lentiviruses license mason mlv mpmv nxt pfizer pol polyprotein polyribosomes polysome polysomes pr65gag quantitated retrovirus retroviruses shuttling srp20 synergized synthesize unspliced xmrv
Tagcloud (Difference) ?		betaretrovirus cte gag gammaretroviral gammaretrovirus gammaretroviruses isogenic lentiviruses license mason mlv mpmv nxt pfizer pol polyprotein polyribosomes polysome polysomes pr65gag quantitated retrovirus retroviruses shuttling srp20 synergized synthesize unspliced xmrv
Tagcloud (Intersection) ?