NXF1 and TNPO1

Number of citations of the paper that reports this interaction (PMID 10668806)
123

Data Source:
BioGRID (pull down, pull down)
HPRD (in vitro, in vivo)

		NXF1	TNPO1
Gene Name		nuclear RNA export factor 1	transportin 1
Image
Gene Ontology Annotations	Cellular Component	Transcription Export Complex Nuclear Pore Nucleoplasm Cytosol Nuclear Speck Nuclear Inclusion Body	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	Nucleotide Binding MRNA Binding Nucleocytoplasmic Transporter Activity Protein Binding Poly(A) RNA Binding	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Poly(A) RNA Binding
	Biological Process	MRNA Export From Nucleus Gene Expression Viral Process Poly(A)+ MRNA Export From Nucleus	Protein Import Into Nucleus, Translocation Organelle Organization Gene Expression Viral Process
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript Processing of Capped Intron-Containing Pre-mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA derived from an Intron-Containing Transcript Transport of Mature mRNAs Derived from Intronless Transcripts Transport of the SLBP independent Mature mRNA Transport of Mature Transcript to Cytoplasm	Regulation of mRNA stability by proteins that bind AU-rich elements Organelle biogenesis and maintenance Assembly of the primary cilium Tristetraprolin (TTP) destabilizes mRNA Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		51 interactors: ALYREF CSNK2A1 DHX9 DVL3 EIF4A3 ELAVL4 ESRRA GFAP HNRNPUL1 IMPA1 IPO11 IPO4 KCTD5 KRT40 LDOC1 MAGOH MAP1A MAP1B MID2 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A SGTA SH2D3A SRSF1 SRSF3 SRSF7 STRAP THOC5 TIFA TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN4 UPF3A XIST ZBED2	17 interactors: ELAVL1 HIST2H2BE HIST3H3 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19
Entrez ID		10482	3842
HPRD ID		04035	04210
Ensembl ID		ENSG00000162231	ENSG00000083312
Uniprot IDs		Q59E96 Q9UBU9	Q92973
PDB IDs		1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7	1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ
Enriched GO Terms of Interacting Partners?		RNA Transport RNA Localization MRNA Transport Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Nuclear Export MRNA Export From Nucleus Cytoplasmic Transport Intracellular Transport MRNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Establishment Of Localization In Cell RNA Processing Gene Expression Cellular Localization Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing Viral Process RNA 3'-end Processing Mitotic Nuclear Envelope Disassembly DNA-templated Transcription, Termination Viral Life Cycle RNA Metabolic Process Nuclear Envelope Disassembly Regulation Of MRNA Splicing, Via Spliceosome Nuclear Import Nuclear Envelope Organization Glucose Transport Nucleobase-containing Compound Metabolic Process Hexose Transport Regulation Of MRNA Processing Viral Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Glucose Transport Regulation Of RNA Splicing Transport Cellular Nitrogen Compound Metabolic Process Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Intracellular Transport Of Virus Regulation Of Alternative MRNA Splicing, Via Spliceosome Protein Import Nitrogen Compound Metabolic Process Protein Localization To Nucleus	Cytoplasmic Transport Viral Life Cycle Viral Process Viral Transcription Intracellular Transport Establishment Of Protein Localization To Organelle MRNA Transport RNA Transport Protein Targeting Nucleocytoplasmic Transport Nuclear Transport RNA Localization Protein Localization To Organelle Establishment Of Localization In Cell Nuclear Import Cellular Localization Gene Expression Intracellular Protein Transport Protein Transport Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Nuclear Export Nuclear Envelope Disassembly Membrane Organization Cellular Protein Localization Protein Localization Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Regulation Of Glucose Transport Establishment Of Protein Localization To Endoplasmic Reticulum MRNA Metabolic Process Protein Import Into Nucleus Transport Nucleus Organization Protein Localization To Endoplasmic Reticulum Carbohydrate Transport Protein Import Protein Targeting To Membrane Protein Localization To Nucleus Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Nuclear Pore Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process
Tagcloud ?		betaretrovirus cte gag gammaretroviral gammaretrovirus gammaretroviruses isogenic lentiviruses license mason mlv mpmv nxt pfizer pol polyprotein polyribosomes polysome polysomes pr65gag quantitated retrovirus retroviruses shuttling srp20 synergized synthesize unspliced xmrv	box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately
Tagcloud (Difference) ?		betaretrovirus cte gag gammaretroviral gammaretrovirus gammaretroviruses isogenic lentiviruses license mason mlv mpmv nxt pfizer pol polyprotein polyribosomes polysome polysomes pr65gag quantitated retrovirus retroviruses shuttling srp20 synergized synthesize unspliced xmrv	box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately
Tagcloud (Intersection) ?