SRSF3 and HNRNPK

Number of citations of the paper that reports this interaction (PMID 10809782)
25

Data Source:
HPRD (two hybrid)

		SRSF3	HNRNPK
Gene Name		serine/arginine-rich splicing factor 3	heterogeneous nuclear ribonucleoprotein K
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nuclear Chromatin Podosome Nucleus Nucleoplasm Cytoplasm Focal Adhesion Membrane Cell Projection Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Single-stranded DNA Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing	MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Processing Signal Transduction RNA Splicing Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance Viral Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: APP CHD1 CLK1 EXOSC6 GEMIN2 HNRNPK IL7R NXF1 PCBP1 PCBP2 PRPF38A RBM7 RBMY1A1 SCAF11 SREK1 SRPK1 SRPK2 SRSF2 TRA2B YWHAB YWHAG YWHAQ	107 interactors: ABI2 APBB1 AQP5 BTRC C6orf226 CBLB CCAR1 CCDC33 CDKN1A CEBPB CIRBP CNNM3 CSK CTNNBL1 DALRD3 DDX1 DDX17 DDX5 DHX9 DIDO1 DOCK2 EIF3F ELAVL1 FBXL18 FYN GFI1B GRAP2 GRB2 GZMA GZMK HCK HIST3H3 HMGB1 HNRNPA0 HNRNPD HNRNPL HNRNPLL ITK ITSN2 KHDRBS1 KHDRBS2 KHDRBS3 LYN MAPK10 MARK4 MATR3 NCK2 NEDD4 NPDC1 PABPC1 PCBP1 PCBP2 PCDHB14 PELI2 PIN1 PPP1R10 PRKCD PRMT1 PRPF31 PRPF40A PRR3 PTBP1 QKI RALY RASD1 RBFOX2 RBM10 RBM3 RBM4 RBM41 RBM42 RBM7 RBMX RBMY1A1 RBMY1F RNA18S5 RNA28S5 RTP5 SAFB SF1 SMAD3 SNRPA SORBS3 SPG7 SRC SREK1 SRRT SRSF3 SUMO1 SYNCRIP TBP TCERG1 TERF2IP TYK2 U2AF1 U2AF2 UBE2I VAV1 WBP4 WWOX YBX1 YTHDC1 YWHAQ ZFC3H1 ZNF385C ZNF792 ZNRF2P1
Entrez ID		6428	3190
HPRD ID		04530	02834
Ensembl ID			ENSG00000165119
Uniprot IDs		B2R6F3 P84103	B4DFF1 B4DUQ1 P61978 Q6IBN1
PDB IDs		2I2Y 2I38	1J5K 1KHM 1ZZI 1ZZJ 1ZZK
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Nitrogen Compound Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrion Organization Spliceosomal Complex Assembly Regulation Of Mitochondrion Organization Immune Response Positive Regulation Of Viral Genome Replication Ribonucleoprotein Complex Biogenesis Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Intrinsic Apoptotic Signaling Pathway Innate Immune Response Positive Regulation Of Apoptotic Signaling Pathway Regulation Of RNA Metabolic Process Negative Regulation Of Viral Genome Replication Cellular Metabolic Process Nuclear Speck Organization Positive Regulation Of Intracellular Transport Immunoglobulin Production Cellular Process MRNA Export From Nucleus Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Intracellular Transport Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Interleukin-7-mediated Signaling Pathway RNA Export From Nucleus Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Positive Regulation Of Cell Death	RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Immune Response Positive Regulation Of Metabolic Process MRNA Stabilization Innate Immune Response Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Peptidyl-tyrosine Autophosphorylation Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of RNA Metabolic Process Metabolic Process Regulation Of Translation Negative Regulation Of Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Immune System Process Positive Regulation Of Gene Expression Regulation Of Immune System Process Defense Response Fc Receptor Signaling Pathway Positive Regulation Of Signal Transduction T Cell Costimulation Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		1alpha activate alter atpase cadherin caffeine cardiac conferred depletion detailed digoxin g2 glycosides governing hela hypoxia isoform mesenchymal modulate modulated na p53alpha p53beta pumping repositioning snail splicing switch transition	associates boosted consequently cpg dnmt1 facilitated h3k9 h3k9me3 heterochromatin impairs insight instead intergenic lincrna link lncrnas methyltransferase noncoding notably p21 pluripotency prevents profiling promoters reprogramming rnas setdb1 somatic sustaining
Tagcloud (Difference) ?		1alpha activate alter atpase cadherin caffeine cardiac conferred depletion detailed digoxin g2 glycosides governing hela hypoxia isoform mesenchymal modulate modulated na p53alpha p53beta pumping repositioning snail splicing switch transition	associates boosted consequently cpg dnmt1 facilitated h3k9 h3k9me3 heterochromatin impairs insight instead intergenic lincrna link lncrnas methyltransferase noncoding notably p21 pluripotency prevents profiling promoters reprogramming rnas setdb1 somatic sustaining
Tagcloud (Intersection) ?