NXF1 and SH2D3A

Number of citations of the paper that reports this interaction (PMID 11875519)
22

Data Source:
BioGRID (pull down)

		NXF1	SH2D3A
Gene Name		nuclear RNA export factor 1	SH2 domain containing 3A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex Nuclear Pore Nucleoplasm Cytosol Nuclear Speck Nuclear Inclusion Body
	Molecular Function	Nucleotide Binding MRNA Binding Nucleocytoplasmic Transporter Activity Protein Binding Poly(A) RNA Binding	SH3/SH2 Adaptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	MRNA Export From Nucleus Gene Expression Viral Process Poly(A)+ MRNA Export From Nucleus	JNK Cascade Small GTPase Mediated Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript Processing of Capped Intron-Containing Pre-mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA derived from an Intron-Containing Transcript Transport of Mature mRNAs Derived from Intronless Transcripts Transport of the SLBP independent Mature mRNA Transport of Mature Transcript to Cytoplasm
Drugs
Diseases
GWAS
Protein-Protein Interactions		51 interactors: ALYREF CSNK2A1 DHX9 DVL3 EIF4A3 ELAVL4 ESRRA GFAP HNRNPUL1 IMPA1 IPO11 IPO4 KCTD5 KRT40 LDOC1 MAGOH MAP1A MAP1B MID2 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A SGTA SH2D3A SRSF1 SRSF3 SRSF7 STRAP THOC5 TIFA TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN4 UPF3A XIST ZBED2	4 interactors: BCAR1 EGFR ERBB2 NXF1
Entrez ID		10482	10045
HPRD ID		04035	05283
Ensembl ID		ENSG00000162231	ENSG00000125731
Uniprot IDs		Q59E96 Q9UBU9	A8K2M8 B4DRS7 Q9BRG2
PDB IDs		1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7
Enriched GO Terms of Interacting Partners?		RNA Transport RNA Localization MRNA Transport Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Nuclear Export MRNA Export From Nucleus Cytoplasmic Transport Intracellular Transport MRNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Establishment Of Localization In Cell RNA Processing Gene Expression Cellular Localization Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing Viral Process RNA 3'-end Processing Mitotic Nuclear Envelope Disassembly DNA-templated Transcription, Termination Viral Life Cycle RNA Metabolic Process Nuclear Envelope Disassembly Regulation Of MRNA Splicing, Via Spliceosome Nuclear Import Nuclear Envelope Organization Glucose Transport Nucleobase-containing Compound Metabolic Process Hexose Transport Regulation Of MRNA Processing Viral Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Glucose Transport Regulation Of RNA Splicing Transport Cellular Nitrogen Compound Metabolic Process Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Intracellular Transport Of Virus Regulation Of Alternative MRNA Splicing, Via Spliceosome Protein Import Nitrogen Compound Metabolic Process Protein Localization To Nucleus	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Cellular Response To Growth Factor Stimulus Chemotaxis Response To Growth Factor Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Proliferation Alkanesulfonate Metabolic Process Regulation Of Immune Response Phosphatidylinositol-mediated Signaling Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Glial Cell Differentiation Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Response To Fibroblast Growth Factor Protein Autophosphorylation Positive Regulation Of MAP Kinase Activity Fc-epsilon Receptor Signaling Pathway Locomotion Gliogenesis Negative Regulation Of Immature T Cell Proliferation In Thymus Activation Of Phospholipase A2 Activity Regulation Of Immune System Process Fc Receptor Signaling Pathway Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Peptidyl-tyrosine Phosphorylation Signal Transduction By Phosphorylation Regulation Of Epithelial Cell Proliferation Regulation Of MAP Kinase Activity Response To Cobalamin Response To UV-A Movement Of Cell Or Subcellular Component Response To Hydroxyisoflavone Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Hepatocyte Growth Factor Receptor Signaling Pathway Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Cellular Component Movement Regulation Of Cell Growth Positive Regulation Of Locomotion
Tagcloud ?		betaretrovirus cte gag gammaretroviral gammaretrovirus gammaretroviruses isogenic lentiviruses license mason mlv mpmv nxt pfizer pol polyprotein polyribosomes polysome polysomes pr65gag quantitated retrovirus retroviruses shuttling srp20 synergized synthesize unspliced xmrv
Tagcloud (Difference) ?		betaretrovirus cte gag gammaretroviral gammaretrovirus gammaretroviruses isogenic lentiviruses license mason mlv mpmv nxt pfizer pol polyprotein polyribosomes polysome polysomes pr65gag quantitated retrovirus retroviruses shuttling srp20 synergized synthesize unspliced xmrv
Tagcloud (Intersection) ?