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HNRNPL and PTBP1
Number of citations of the paper that reports this interaction (PubMedID
35271311
)
106
Data Source:
BioGRID
(biochemical, affinity chromatography technology)
HPRD
(in vitro, two hybrid)
HNRNPL
PTBP1
Description
heterogeneous nuclear ribonucleoprotein L
polypyrimidine tract binding protein 1
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Ribonucleoprotein Granule
Pronucleus
Synapse
Extracellular Exosome
Ribonucleoprotein Complex
Nucleus
Nucleoplasm
Nucleolus
Membrane
Extracellular Exosome
Molecular Function
Transcription Cis-regulatory Region Binding
Nucleic Acid Binding
RNA Binding
MRNA Binding
Protein Binding
Pre-mRNA Intronic Binding
Nucleic Acid Binding
RNA Binding
MRNA Binding
Protein Binding
Poly-pyrimidine Tract Binding
Pre-mRNA Binding
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
RNA Processing
MRNA Processing
Regulation Of RNA Splicing
Negative Regulation Of DNA-templated Transcription
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
Neurogenesis
Negative Regulation Of RNA Splicing
Regulation Of RNA Splicing
Regulation Of Cell Differentiation
Negative Regulation Of Neuron Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of Calcineurin-NFAT Signaling Cascade
IRES-dependent Viral Translational Initiation
Negative Regulation Of MRNA Metabolic Process
Pathways
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
FGFR2 alternative splicing
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Copper
Diseases
GWAS
Anti-saccade response (
29064472
)
Logical memory (immediate recall) in mild cognitive impairment (
29274321
)
Alanine aminotransferase levels (
33547301
34315874
)
Aspartate aminotransferase levels (
34315874
)
Hematocrit (
27863252
32888494
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Red blood cell count (
32888494
)
Refractive error (
32231278
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
94 interacting genes:
APEX1
CEBPA
CREBBP
CSE1L
CSNK2A1
FBXO16
FGFR3
H3-4
HMG20B
HMGA1
HNRNPA2B1
HNRNPK
IL7R
LINC00624
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
OGT
PCBP2
PJA1
PTBP1
SUMO2
SUMO4
USP7
118 interacting genes:
APBB1
APP
CALCOCO2
CASP3
CCAT1
CEBPA
FOXP1
FUS
H3-4
HIF1A
HMGA1
HMGA2
HNRNPAB
HNRNPL
HNRNPLL
IL7R
LIN28A
LINC00624
LINC00839
LINC01554
MARK4
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NDUFV3
NONO
OGT
PCBP1
PCBP2
PCBP3
PKLR
PRKACA
PRPF40A
QKI
RAVER1
RAVER2
RBFOX2
RBM10
RNF10
SERPINB5
SFPQ
SNCA
SNRPA
SRPK2
SUMO2
TRAK1
USP36
ZC3H8
ZMYM2
Entrez ID
3191
5725
HPRD ID
04360
02823
Ensembl ID
ENSG00000104824
ENSG00000011304
Uniprot IDs
A0A3B3ITJ4
P14866
Q6NTA2
A0A7I2V621
P26599
PDB IDs
3R27
3TO8
7EVR
1QM9
1SJQ
1SJR
2AD9
2ADB
2ADC
2EVZ
2N3O
3ZZY
3ZZZ
8BGF
8BWF
Enriched GO Terms of Interacting Partners
?
MiRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA 3'-UTR Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Metabolic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Extracellular Vesicle
Negative Regulation Of Translation
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
MRNA Destabilization
Regulation Of Metabolic Process
RNA Destabilization
Positive Regulation Of MRNA Catabolic Process
Negative Regulation Of Cell Migration
Negative Regulation Of Cell Motility
Negative Regulation Of Locomotion
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Negative Regulation Of Cytokine Production
Positive Regulation Of MRNA Metabolic Process
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of Angiogenesis
Regulation Of Vasculature Development
Regulation Of Translation
Regulation Of MRNA Stability
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Developmental Process
Regulation Of RNA Stability
Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Multicellular Organismal Process
Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of MRNA Metabolic Process
Negative Regulation Of Signal Transduction
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Endothelial Cell Migration
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
MiRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
MRNA 3'-UTR Binding
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
MiRNA-mediated Gene Silencing By MRNA Destabilization
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Extracellular Vesicle
Negative Regulation Of Translation
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
MRNA Destabilization
Positive Regulation Of MRNA Catabolic Process
RNA Destabilization
Negative Regulation Of Multicellular Organismal Process
Negative Regulation Of Cytokine Production
Regulation Of Angiogenesis
Regulation Of Vasculature Development
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Positive Regulation Of MRNA Metabolic Process
Negative Regulation Of Cell Migration
Regulation Of MRNA Stability
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Developmental Process
Negative Regulation Of Cell Motility
Regulation Of Translation
Regulation Of RNA Stability
Negative Regulation Of Locomotion
Regulation Of MRNA Metabolic Process
Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Endothelial Cell Migration
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Signal Transduction
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Cytokine Production
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Cell Migration
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