HNRNPD and PRDX3

Number of citations of the paper that reports this interaction (PubMedID 15231747)
47

Data Source:
BioGRID (two hybrid)

		HNRNPD	PRDX3
Description		heterogeneous nuclear ribonucleoprotein D	peroxiredoxin 3
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Synapse Glutamatergic Synapse MCRD-mediated MRNA Stability Complex Ribonucleoprotein Complex	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Endosome Early Endosome Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	Nucleic Acid Binding DNA Binding Minor Groove Of Adenine-thymine-rich DNA Binding Chromatin Binding RNA Binding MRNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding Telomeric DNA Binding Histone Deacetylase Binding	Peroxidase Activity Protein Binding Thioredoxin Peroxidase Activity Antioxidant Activity Oxidoreductase Activity Protein Kinase Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Peroxiredoxin Activity NADH-dependent Peroxiredoxin Activity Thioredoxin-dependent Peroxiredoxin Activity
	Biological Process	Liver Development Regulation Of DNA-templated Transcription RNA Processing RNA Catabolic Process Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cerebellum Development Positive Regulation Of Telomere Maintenance Via Telomerase Response To Estradiol Regulation Of Circadian Rhythm Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Response To Calcium Ion Response To Electrical Stimulus 3'-UTR-mediated MRNA Destabilization CRD-mediated MRNA Stabilization Cellular Response To Amino Acid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Nitric Oxide Circadian Regulation Of Translation Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Response To Rapamycin Positive Regulation Of Telomere Capping Response To Sodium Phosphate Cellular Response To Putrescine Hepatocyte Dedifferentiation Positive Regulation Of Cytoplasmic Translation	Maternal Placenta Development Response To Oxidative Stress Mitochondrion Organization Positive Regulation Of Cell Population Proliferation Myeloid Cell Differentiation Response To Lipopolysaccharide Negative Regulation Of Kinase Activity Cellular Response To Oxidative Stress Cellular Response To Reactive Oxygen Species Response To Hydrogen Peroxide Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Cell Redox Homeostasis Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Mitochondrial Membrane Potential Cellular Oxidant Detoxification
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Detoxification of Reactive Oxygen Species
Drugs		Artenimol
Diseases
GWAS		Chronotype ( 30696823) Coronary artery disease ( 32469254 33020668) Liver enzyme levels (alkaline phosphatase) ( 33972514) Morning person ( 30696823) Refractive error ( 32231278)	Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		98 interacting genes: ABCC10 ACTB ADGRE5 ARF4 B3GAT3 BET1L BRCA1 C1QBP CAPN1 CD81 CEBPA CINP COG7 COL18A1 CSDE1 CTSB CUTA DGCR2 DHX30 DMAC1 EEF2 ERG ESR1 EXOSC4 FBXL15 FILNC1 FLNA FNDC3B FOS FOXP1 GSK3B GTF3C3 GTSE1 GUK1 HBZ HDAC1 HIRA HMGA1 HNRNPH3 HSPA4 HSPB1 HSPB2 IGF2BP2 IL6 IL7R IMMP2L IMMT ING4 LDHA LINC01232 LSM5 MAP2K1 MAPK6 MEOX2 MPP1 MTA2 MYC NEDD4L NTMT1 OGT P4HB PABPC1 PCBP1 PCBP2 PCSK7 PDLIM7 PEX10 PPOX PRDX3 PRKACA PTBP2 PYCR1 RALY RPSA SAFB SDF2 SEPTIN9 SF3B4 SFN SHISA5 SLC27A5 SLC3A2 SNAPC4 SREK1 SUMO4 SYNCRIP TNF TNPO1 TOP2A TRN-GTT2-7 TSEN34 UBE2I UCP3 UQCRC1 VEGFA VHL YBX1 ZMYM4	15 interacting genes: CDC42 CUL4B FANCC GORASP2 HNRNPD MAGEA11 MAP3K13 NEK6 NR3C1 PRDX4 PTEN RPS6KC1 SUMO4 TNFRSF1A ZNF77
Entrez ID		3184	10935
HPRD ID		03206	05305
Ensembl ID		ENSG00000138668	ENSG00000165672
Uniprot IDs		Q14103	A0A384MTR2 P30048
PDB IDs		1HD0 1HD1 1IQT 1WTB 1X0F 2Z5N 5IM0	5JCG 5UCX
Enriched GO Terms of Interacting Partners?		RNA Binding CRD-mediated MRNA Stabilization Macromolecule Metabolic Process Positive Regulation Of Translation Ribonucleoprotein Complex Positive Regulation Of Cytoplasmic Translation Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression MRNA Metabolic Process Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Programmed Cell Death RNA Metabolic Process Nucleic Acid Binding Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Response To Stress Negative Regulation Of Apoptotic Process Cellular Response To Stress Regulation Of Cytoplasmic Translation MCRD-mediated MRNA Stability Complex Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II CRD-mediated MRNA Stability Complex Positive Regulation Of Gene Expression Transcription Coregulator Binding Regulation Of Gene Expression Regulation Of Translation Nucleic Acid Metabolic Process Regulation Of MiRNA Transcription Focal Adhesion Negative Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II RNA Splicing Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Processing Regulation Of Macromolecule Biosynthetic Process Spliceosomal Complex Nucleoplasm Negative Regulation Of Catabolic Process Regulation Of DNA-templated Transcription Regulation Of MiRNA Metabolic Process	Maternal Behavior Parental Behavior Dendritic Spine Morphogenesis Regulation Of Mitotic Cell Cycle Protein Kinase Binding Macrophage Differentiation Neuron Projection Organization Dendritic Spine Organization Postsynapse Organization Response To Stress Astrocyte Differentiation Nuclear Glucocorticoid Receptor Activity Reproductive Behavior Response To Electrical Stimulus Hepatocyte Dedifferentiation Cellular Response To Putrescine Regulation Of Cellular Senescence Negative Regulation Of Synaptic Vesicle Clustering Positive Regulation Of Branching Morphogenesis Of A Nerve
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?