HNRNPD and B3GAT3

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		HNRNPD	B3GAT3
Gene Name		heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	beta-1,3-glucuronyltransferase 3
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Ribonucleoprotein Complex Extracellular Vesicular Exosome	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Telomeric DNA Binding Poly(A) RNA Binding	Protein Binding Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Glucuronosyltransferase Activity Metal Ion Binding Protein Phosphatase Activator Activity
	Biological Process	MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing RNA Catabolic Process RNA Splicing Gene Expression Regulation Of Circadian Rhythm Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Transcription, DNA-templated Circadian Regulation Of Translation	Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process Protein Glycosylation Pathogenesis Heparan Sulfate Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Positive Regulation Of Catalytic Activity Small Molecule Metabolic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Intracellular Protein Transport
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Heparan sulfate/heparin (HS-GAG) metabolism Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Defective CHST6 causes MCDC1 Glycogen storage diseases MPS IIID - Sanfilippo syndrome D A tetrasaccharide linker sequence is required for GAG synthesis MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B Defective CHSY1 causes TPBS MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs			Udp-Glucuronic Acid Uridine-5\'-Diphosphate
Diseases
GWAS
Protein-Protein Interactions		92 interactors: ABCC10 ACTB ARF4 B3GAT3 BCL2 BET1L BRCA1 C1QBP CAPN1 CD81 CD97 CINP COG7 COL18A1 CSDE1 CTSB CUTA DGCR2 DHX30 EEF2 EIF4G1 ERG EXOSC4 FBXL15 FLNA GSK3B GTF3C3 GTSE1 GUK1 HBZ HDAC1 HIRA HMGA1 HNRNPC HNRNPF HNRNPH3 HNRNPK HNRNPU HSPA4 HSPB1 HSPB2 IGF2BP2 IL7R IMMP2L IMMT ING4 LDHA LSM5 MAP2K1 MAPK6 MEOX2 MPP1 MTA2 MYC NTMT1 P4HB PABPC1 PCBP1 PCBP2 PCSK7 PDLIM7 PEX10 PPOX PRDX3 PRKACA PTBP2 PYCR1 RALY RPSA SAFB SDF2 SEPT9 SF3B4 SFN SHISA5 SLC27A5 SLC3A2 SNAPC4 SNRPC SREK1 SUMO4 SYNCRIP TMEM261 TNPO1 TRN-GTT2-1 TSEN34 U2AF2 UBE2I UQCRC1 VEGFA VHL YBX1	2 interactors: HNRNPD SEC22B
Entrez ID		3184	26229
HPRD ID		03206	07564
Ensembl ID			ENSG00000149541
Uniprot IDs		Q14103	B7ZAB3 O94766
PDB IDs		1HD0 1HD1 1IQT 1WTB 1X0F 2Z5N	1FGG 1KWS 3CU0
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process RNA Splicing MRNA Processing RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Heterocycle Metabolic Process Cellular Metabolic Process Gene Expression Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Posttranscriptional Regulation Of Gene Expression Metabolic Process MRNA Stabilization Response To Stress Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression CRD-mediated MRNA Stabilization Cellular Process Positive Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Death Positive Regulation Of Protein Export From Nucleus Nuclear-transcribed MRNA Catabolic Process Regulation Of Apoptotic Process MRNA Catabolic Process Viral Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing Positive Regulation Of Cellular Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Organelle Organization Regulation Of Metabolic Process Response To Wounding Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cell Death RNA Catabolic Process Negative Regulation Of RNA Splicing Chromatin Remodeling Positive Regulation Of Metabolic Process Positive Regulation Of Mitochondrion Organization Regulation Of Translation	Circadian Regulation Of Translation
Tagcloud ?		abcb7 advance alas2 asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Difference) ?		abcb7 advance alas2 asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Intersection) ?