Wiki-Pi
About
Search
People
Updates
Search
HNRNPD and PRKACA
Number of citations of the paper that reports this interaction (PubMedID
11903055
)
44
Data Source:
HPRD
(in vitro)
HNRNPD
PRKACA
Description
heterogeneous nuclear ribonucleoprotein D
protein kinase cAMP-activated catalytic subunit alpha
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Postsynaptic Density
Synapse
Glutamatergic Synapse
MCRD-mediated MRNA Stability Complex
Ribonucleoprotein Complex
Acrosomal Vesicle
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Centrosome
Cytosol
Plasma Membrane
Cilium
Axoneme
CAMP-dependent Protein Kinase Complex
Membrane
Nuclear Speck
Cytoplasmic Vesicle
Motile Cilium
Nucleotide-activated Protein Kinase Complex
Neuromuscular Junction
Calcium Channel Complex
Sperm Flagellum
Cell Projection
Plasma Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Sperm Midpiece
Ciliary Base
Postsynapse
Glutamatergic Synapse
Molecular Function
Nucleic Acid Binding
DNA Binding
Minor Groove Of Adenine-thymine-rich DNA Binding
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
MRNA 3'-UTR AU-rich Region Binding
Telomeric DNA Binding
Histone Deacetylase Binding
Nucleotide Binding
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
CAMP-dependent Protein Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Protein Kinase Binding
Protein Domain Specific Binding
Manganese Ion Binding
Ubiquitin Protein Ligase Binding
Protein Kinase A Regulatory Subunit Binding
Channel Activator Activity
Protein Serine Kinase Activity
Biological Process
Liver Development
Regulation Of DNA-templated Transcription
RNA Processing
RNA Catabolic Process
Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Cerebellum Development
Positive Regulation Of Telomere Maintenance Via Telomerase
Response To Estradiol
Regulation Of Circadian Rhythm
Regulation Of MRNA Stability
Positive Regulation Of Translation
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Response To Calcium Ion
Response To Electrical Stimulus
3'-UTR-mediated MRNA Destabilization
CRD-mediated MRNA Stabilization
Cellular Response To Amino Acid Stimulus
Cellular Response To Estradiol Stimulus
Cellular Response To Nitric Oxide
Circadian Regulation Of Translation
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Response To Rapamycin
Positive Regulation Of Telomere Capping
Response To Sodium Phosphate
Cellular Response To Putrescine
Hepatocyte Dedifferentiation
Positive Regulation Of Cytoplasmic Translation
Mesoderm Formation
Neural Tube Closure
Regulation Of Heart Rate
Renal Water Homeostasis
MRNA Processing
Protein Phosphorylation
Protein Export From Nucleus
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Regulation Of Macroautophagy
Peptidyl-serine Phosphorylation
Cytokine-mediated Signaling Pathway
Intracellular Potassium Ion Homeostasis
Cellular Response To Nutrient Levels
Positive Regulation Of Insulin Secretion
Negative Regulation Of Interleukin-2 Production
High-density Lipoprotein Particle Assembly
Cellular Response To Heat
Mitochondrial Protein Catabolic Process
Interleukin-2-mediated Signaling Pathway
TORC1 Signaling
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cholesterol Biosynthetic Process
Regulation Of Osteoblast Differentiation
Positive Regulation Of Gluconeogenesis
Negative Regulation Of Smoothened Signaling Pathway
Positive Regulation Of Protein Export From Nucleus
Sperm Capacitation
Positive Regulation Of Phagocytosis
Modulation Of Chemical Synaptic Transmission
Positive Regulation Of Calcium-mediated Signaling
Regulation Of Cell Cycle
Regulation Of Cardiac Muscle Contraction
Regulation Of Proteasomal Protein Catabolic Process
Cellular Response To Cold
Regulation Of Protein Processing
Cellular Response To Glucose Stimulus
Cellular Response To Parathyroid Hormone Stimulus
Cellular Response To Glucagon Stimulus
Cellular Response To Epinephrine Stimulus
Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Vascular Endothelial Cell Response To Laminar Fluid Shear Stress
Postsynaptic Modulation Of Chemical Synaptic Transmission
CAMP/PKA Signal Transduction
Regulation Of Cardiac Conduction
Negative Regulation Of TORC1 Signaling
Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate
Protein Localization To Lipid Droplet
Regulation Of Bicellular Tight Junction Assembly
Pathways
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
PKA-mediated phosphorylation of CREB
PKA-mediated phosphorylation of key metabolic factors
Triglyceride catabolism
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Rap1 signalling
Regulation of insulin secretion
Vasopressin regulates renal water homeostasis via Aquaporins
VEGFA-VEGFR2 Pathway
CREB1 phosphorylation through the activation of Adenylate Cyclase
CREB1 phosphorylation through the activation of Adenylate Cyclase
Interleukin-3, Interleukin-5 and GM-CSF signaling
Ion homeostasis
Degradation of GLI1 by the proteasome
Degradation of GLI2 by the proteasome
GLI3 is processed to GLI3R by the proteasome
Hedgehog 'off' state
Anchoring of the basal body to the plasma membrane
CD209 (DC-SIGN) signaling
MAPK6/MAPK4 signaling
RET signaling
AURKA Activation by TPX2
HDL assembly
ROBO receptors bind AKAP5
Loss of phosphorylation of MECP2 at T308
Regulation of MECP2 expression and activity
GPER1 signaling
GPER1 signaling
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
ADORA2B mediated anti-inflammatory cytokines production
ADORA2B mediated anti-inflammatory cytokines production
FCGR3A-mediated IL10 synthesis
FCGR3A-mediated IL10 synthesis
Factors involved in megakaryocyte development and platelet production
Mitochondrial protein degradation
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs
Artenimol
Pentanal
Balanol Analog 2
3-[(3-sec-butyl-4-hydroxybenzoyl)amino]azepan-4-yl 4-(2-hydroxy-5-methoxybenzoyl)benzoate
Phosphonothreonine
Balanol Analog 1
3,5-Diiodotyrosine
Balanol
Dexfosfoserine
S,S-(2-Hydroxyethyl)Thiocysteine
Hydroxyfasudil
(2S)-1-(3H-Indol-3-yl)-3-{[5-(6-isoquinolinyl)-3-pyridinyl]oxy}-2-propanamine
(2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine
(1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE
(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
(1S)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE
N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE
3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-1H-indol-3-yl}-1H-pyrrole-2,5-dione
(4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE
N-METHYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE
(S)-1-PHENYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE
6-{4-[4-(4-CHLOROPHENYL)PIPERIDIN-4-YL]PHENYL}-9H-PURINE
(2R)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine
(2S)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine
4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE
(2R)-2-(4-CHLOROPHENYL)-2-PHENYLETHANAMINE
(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE
ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE
H-89
5-(2-methylpiperazine-1-sulfonyl)isoquinoline
N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE
2-[4-(3-METHYL-1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE
(2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
3-pyridin-4-yl-1H-indazole
5-benzyl-1,3-thiazol-2-amine
1-[4-(4-chlorophenyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
1-[4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium
Fasudil
Myristic acid
A-674563
3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.] PYRAZOLE
Y-27632
Ellagic acid
Fostamatinib
Diseases
GWAS
Chronotype (
30696823
)
Coronary artery disease (
32469254
33020668
)
Liver enzyme levels (alkaline phosphatase) (
33972514
)
Morning person (
30696823
)
Refractive error (
32231278
)
Interacting Genes
98 interacting genes:
ABCC10
ACTB
ADGRE5
ARF4
B3GAT3
BET1L
BRCA1
C1QBP
CAPN1
CD81
CEBPA
CINP
COG7
COL18A1
CSDE1
CTSB
CUTA
DGCR2
DHX30
DMAC1
EEF2
ERG
ESR1
EXOSC4
FBXL15
FILNC1
FLNA
FNDC3B
FOS
FOXP1
GSK3B
GTF3C3
GTSE1
GUK1
HBZ
HDAC1
HIRA
HMGA1
HNRNPH3
HSPA4
HSPB1
HSPB2
IGF2BP2
IL6
IL7R
IMMP2L
IMMT
ING4
LDHA
LINC01232
LSM5
MAP2K1
MAPK6
MEOX2
MPP1
MTA2
MYC
NEDD4L
NTMT1
OGT
P4HB
PABPC1
PCBP1
PCBP2
PCSK7
PDLIM7
PEX10
PPOX
PRDX3
PRKACA
PTBP2
PYCR1
RALY
RPSA
SAFB
SDF2
SEPTIN9
SF3B4
SFN
SHISA5
SLC27A5
SLC3A2
SNAPC4
SREK1
SUMO4
SYNCRIP
TNF
TNPO1
TOP2A
TRN-GTT2-7
TSEN34
UBE2I
UCP3
UQCRC1
VEGFA
VHL
YBX1
ZMYM4
207 interacting genes:
AANAT
ABCA1
ACLY
ADCY5
ADD1
ADD2
AKAP14
AKAP8L
AKIP1
ANXA7
APC
APOBEC3G
ARFGEF3
ASIC1
ASIC3
ATF1
ATG12
ATP2B1
AURKA
AVPI1
BAD
BCL2
BRAF
CACNA1C
CACNB2
CACNG2
CAD
CALD1
CAMKK2
CCDC88A
CCND1
CDK16
CDKN1A
CETN1
CFTR
CIITA
CLDN3
CLTC
CREB1
CREM
CRK
CSK
CUL5
CYP3A4
DMTN
DNAJC5
DOCK1
DRD1
DSP
EEF2K
EGFR
ERBB3
ESR1
ETV1
FBXW11
FOS
FXYD1
GABRB3
GABRR1
GAD1
GAD2
GFAP
GJA5
GJB1
GLI1
GMFB
GNA13
GNMT
GP1BB
GRIA1
GRIA4
GRK2
GSK3A
GSK3B
GUSB
GYS1
HAND1
HAND2
HDAC1
HDAC8
HIF1A
HMGCR
HMGN1
HMGN2
HNF4A
HNRNPD
HSPA4
HSPD1
IFNAR1
IQGAP1
IRF2
ITCH
ITGA2B
ITGA4
ITPKA
ITPKB
ITPR1
ITPR2
KCNH2
KCNJ12
KCNQ1
KDELR1
KLF1
KLHL3
LCK
LCP1
LIPE
LRP1
MAP2
MAP3K3
MAPT
MBP
MC4R
MEF2D
MEP1B
MGMT
MIP
NDRG1
NFKB1
NHERF2
NIN
NOLC1
NOS1
NOXA1
NR3C1
NSFL1C
NUP85
PARK7
PDC
PDE3A
PDE3B
PDE4B
PDE4D
PDPK1
PFKFB1
PFKFB2
PHKA1
PHOX2A
PKIA
PKIB
PLIN1
PLN
POU2F1
PPP1R10
PPP1R17
PPP1R1B
PPP1R8
PPP1R9B
PRKAR1A
PRKAR2A
PSEN1
PSMD11
PTBP1
PTPN12
PTPN13
PTPN7
PTPRR
RAF1
RANBP9
RAP1A
RAP1B
RAP1GAP
RASGRF1
RASGRP3
RELA
RGS10
RGS13
RGS14
RHOA
RRAD
RSBN1
RYR1
RYR2
SI
SIK1
SIK3
SLC2A2
SLC4A4
SNAP25
SNAPIN
SNPH
SOX9
SPTBN1
SRC
STK11
STMN1
STMN2
STUB1
SYN1
SYN2
TH
THOP1
TNP1
TNP2
TPH1
TPR
TRIM55
TRIM63
TRIP10
UBE3A
UHRF1
USP20
VASP
VIM
VTN
WT1
YWHAZ
Entrez ID
3184
5566
HPRD ID
03206
03382
Ensembl ID
ENSG00000138668
ENSG00000072062
Uniprot IDs
Q14103
A0A8V8TL59
A8K8B9
P17612
PDB IDs
1HD0
1HD1
1IQT
1WTB
1X0F
2Z5N
5IM0
2GU8
3AGL
3AGM
3AMA
3AMB
3L9L
3L9M
3L9N
3MVJ
3NX8
3OOG
3OVV
3OWP
3OXT
3P0M
3POO
3VQH
4AE6
4AE9
4UJ1
4UJ2
4UJ9
4UJA
4UJB
4WB5
4WB6
4WB7
4WB8
5BX6
5BX7
5IZF
5IZJ
5J5X
5N23
5UZK
6BYR
6BYS
6C0U
6FRX
6NO7
6QJ7
6WJF
6WJG
7Y1G
8FE2
8FE5
8FEC
8X5L
Enriched GO Terms of Interacting Partners
?
RNA Binding
CRD-mediated MRNA Stabilization
Macromolecule Metabolic Process
Positive Regulation Of Translation
Ribonucleoprotein Complex
Positive Regulation Of Cytoplasmic Translation
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Gene Expression
MRNA Metabolic Process
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Regulation Of Programmed Cell Death
RNA Metabolic Process
Nucleic Acid Binding
Regulation Of Apoptotic Process
Regulation Of RNA Metabolic Process
Response To Stress
Negative Regulation Of Apoptotic Process
Cellular Response To Stress
Regulation Of Cytoplasmic Translation
MCRD-mediated MRNA Stability Complex
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
CRD-mediated MRNA Stability Complex
Positive Regulation Of Gene Expression
Transcription Coregulator Binding
Regulation Of Gene Expression
Regulation Of Translation
Nucleic Acid Metabolic Process
Regulation Of MiRNA Transcription
Focal Adhesion
Negative Regulation Of Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
RNA Splicing
Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
MRNA Processing
Regulation Of Macromolecule Biosynthetic Process
Spliceosomal Complex
Nucleoplasm
Negative Regulation Of Catabolic Process
Regulation Of DNA-templated Transcription
Regulation Of MiRNA Metabolic Process
Intracellular Signal Transduction
Regulation Of Biological Quality
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Transport
Intracellular Signaling Cassette
Cellular Response To Oxygen-containing Compound
Cytosol
Cytoplasm
Regulation Of Protein Localization
Developmental Process
Signal Transduction
Protein Kinase A Catalytic Subunit Binding
Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Plasma Membrane
System Process
Regulation Of Membrane Potential
Calmodulin Binding
Regulation Of Multicellular Organismal Process
Regulation Of Cellular Localization
Scaffold Protein Binding
Response To Purine-containing Compound
Response To Metal Ion
Learning Or Memory
Cellular Developmental Process
Cell Development
Cellular Response To Growth Factor Stimulus
Regulation Of Blood Circulation
Response To Growth Factor
Learning
Signal Release
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Programmed Cell Death
Neuron Projection
Negative Regulation Of Apoptotic Process
Positive Regulation Of Protein Localization
Regulation Of Heart Contraction
Cognition
Regulation Of G Protein-coupled Receptor Signaling Pathway
Protein Kinase Binding
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Associative Learning
Negative Regulation Of Signal Transduction
Enzyme Binding
Positive Regulation Of Multicellular Organismal Process
Response To Hormone
Response To Peptide Hormone
Biological_process
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?