HNRNPD and PCBP2

Number of citations of the paper that reports this interaction (PMID 10373504)
71

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vivo, in vitro)

		HNRNPD	PCBP2
Gene Name		heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	poly(rC) binding protein 2
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Ribonucleoprotein Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Membrane Ribonucleoprotein Complex Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Telomeric DNA Binding Poly(A) RNA Binding	DNA Binding RNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing RNA Catabolic Process RNA Splicing Gene Expression Regulation Of Circadian Rhythm Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Transcription, DNA-templated Circadian Regulation Of Translation	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression MRNA Metabolic Process Negative Regulation Of Type I Interferon Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Negative Regulation Of Defense Response To Virus Defense Response To Virus
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing Negative regulators of RIG-I/MDA5 signaling mRNA Splicing - Major Pathway Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		92 interactors: ABCC10 ACTB ARF4 B3GAT3 BCL2 BET1L BRCA1 C1QBP CAPN1 CD81 CD97 CINP COG7 COL18A1 CSDE1 CTSB CUTA DGCR2 DHX30 EEF2 EIF4G1 ERG EXOSC4 FBXL15 FLNA GSK3B GTF3C3 GTSE1 GUK1 HBZ HDAC1 HIRA HMGA1 HNRNPC HNRNPF HNRNPH3 HNRNPK HNRNPU HSPA4 HSPB1 HSPB2 IGF2BP2 IL7R IMMP2L IMMT ING4 LDHA LSM5 MAP2K1 MAPK6 MEOX2 MPP1 MTA2 MYC NTMT1 P4HB PABPC1 PCBP1 PCBP2 PCSK7 PDLIM7 PEX10 PPOX PRDX3 PRKACA PTBP2 PYCR1 RALY RPSA SAFB SDF2 SEPT9 SF3B4 SFN SHISA5 SLC27A5 SLC3A2 SNAPC4 SNRPC SREK1 SUMO4 SYNCRIP TMEM261 TNPO1 TRN-GTT2-1 TSEN34 U2AF2 UBE2I UQCRC1 VEGFA VHL YBX1	25 interactors: BARD1 CASK CNBP FLNA HMGA1 HMGA2 HNRNPD HNRNPK HNRNPL NKAP PABPC1 PAXIP1 PCBP1 PRPF40A PTBP1 QKI SF3B2 SLU7 SNRPA SRSF3 SRSF7 WDR77 WDR83 YBX1 YBX3
Entrez ID		3184	5094
HPRD ID		03206	03129
Ensembl ID			ENSG00000197111
Uniprot IDs		Q14103	B4DXP5 F8VZX2 G3V0E8 Q15366
PDB IDs		1HD0 1HD1 1IQT 1WTB 1X0F 2Z5N	2AXY 2JZX 2P2R 2PQU 2PY9
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process RNA Splicing MRNA Processing RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Heterocycle Metabolic Process Cellular Metabolic Process Gene Expression Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Posttranscriptional Regulation Of Gene Expression Metabolic Process MRNA Stabilization Response To Stress Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression CRD-mediated MRNA Stabilization Cellular Process Positive Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Death Positive Regulation Of Protein Export From Nucleus Nuclear-transcribed MRNA Catabolic Process Regulation Of Apoptotic Process MRNA Catabolic Process Viral Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing Positive Regulation Of Cellular Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Organelle Organization Regulation Of Metabolic Process Response To Wounding Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cell Death RNA Catabolic Process Negative Regulation Of RNA Splicing Chromatin Remodeling Positive Regulation Of Metabolic Process Positive Regulation Of Mitochondrion Organization Regulation Of Translation	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of RNA Metabolic Process Transcription, DNA-templated Oncogene-induced Cell Senescence Positive Regulation Of Macromolecule Biosynthetic Process Metabolic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of MRNA Processing MRNA Stabilization Regulation Of Nitrogen Compound Metabolic Process Senescence-associated Heterochromatin Focus Assembly Negative Regulation Of Gene Expression Positive Regulation Of Cellular Senescence Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Aging Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Translation Heterochromatin Assembly Biosynthetic Process MRNA 3'-end Processing Heterochromatin Organization Positive Regulation Of Cellular Metabolic Process Regulation Of MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Translation
Tagcloud ?		abcb7 advance alas2 asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome	9b aip4 atg5 clue coronaviruses cov depended dynamin etiologic evade evades fission havoc hect illustrates localizes manipulates mavs mitochondria orf outbreak proteasomal sars signalosome traf traf3 triggering uncovered usurping
Tagcloud (Difference) ?		abcb7 advance alas2 asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome	9b aip4 atg5 clue coronaviruses cov depended dynamin etiologic evade evades fission havoc hect illustrates localizes manipulates mavs mitochondria orf outbreak proteasomal sars signalosome traf traf3 triggering uncovered usurping
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