CCND1 and CDK4

  • Number of citations of the paper that reports this interaction (PMID 15232106)
  • 88
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)
  • HPRD (in vitro, in vivo)

CCND1

CDK4

Gene Name cyclin D1 cyclin-dependent kinase 4
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Celiac disease and Rheumatoid arthritis ( 21383967)
Protein-Protein Interactions 60 interactors: AKAP8 AR ARID4A ATF2 BRCA1 BRINP1 BTRC CALM1 CAMK1 CCNDBP1 CDK4 CDK6 CDKN1A CDKN1B CDKN1C CDKN2A CRYAB CTNNB1 CUL3 DMTF1 EP300 ESR1 FBXO31 FBXO4 GSK3B HDAC3 HERC5 IFI27 INSM1 KAT2B LPL MAPK11 MCM10 MCM7 MYBL2 NCOA1 NCOA3 NPDC1 ORC4 PCNA POLR1B PRKACA RABEP1 RB1 RBL1 RBL2 RBX1 RFC1 RUNX1 SP1 STAT3 TAF1 THRA THRB TP73 TSC2 UBTF UHRF2 USP2 XPO1 90 interactors: ANKRD12 ANXA7 APLP1 APP ARID4A ATP5B BAG6 BCL11A BIRC5 BMPR1B BRCA1 CAMK1 CAPNS1 CCND1 CCND2 CCND3 CDC37 CDC45 CDC6 CDC7 CDKN1A CDKN1B CDKN1C CDKN2A CDKN2B CDKN2C CDKN2D CEBPA CIB1 CNOT7 DAZAP2 DDAH2 DUSP9 FOXM1 GLI1 H1F0 HIST1H1A HIST1H1D HMGXB3 HOOK1 IFI27 IL15RA LUC7L2 MAPRE2 MARCKS MCM2 MYC MYOD1 MZF1 NCOA2 NOL12 ORC3 OTX2 PGD PKM POLD1 PPP2R1B PRKAR1A PSMD10 PTMA QARS RB1 RBL1 RBL2 RFC1 RFC4 RPL34 SENP3 SERTAD1 SETDB1 SHOX2 SKP1 SLBP SMAD2 SMAD3 SNCA TGFBR1 TK1 TRMT2A TSPYL2 UBTF UHRF2 VTA1 WDR33 ZBTB16 ZNF101 ZNF219 ZNF335 ZNF655 ZSCAN1
Entrez ID 595 1019
HPRD ID 01346 00447
Ensembl ID ENSG00000110092 ENSG00000135446
Uniprot IDs P24385 Q6FI00 P11802 Q6LC83
PDB IDs 2W96 2W99 2W9F 2W9Z 1LD2 2W96 2W99 2W9F 2W9Z 3G33
Enriched GO Terms of Interacting Partners?
Tagcloud ?
11q13  4nqo  7f4  amplicon  amplification  amplified  cavity  chr  distal  example  fgf3  fgf4  heterozygosity  hras1  inbred  inconsistently  involving  loh  murine  neck  nitroquinoline  portion  predispose  scc  strikingly  syntenic  telomeric  thirds  twofold 
aberrantly  acetylglucosaminyltransferase  antigens  bage  ctl  ecto  fig  fm3  fm57  gage  gp100  immunogenic  immunogenicity  in4  maa  mage  mart  melan  melanocyte  melanomas  p15  pbl  permitted  pointing  prame  ref  tab  trp  tyrosinase  uncloned 
Tagcloud (Difference) ?
11q13  4nqo  7f4  amplicon  amplification  amplified  cavity  chr  distal  example  fgf3  fgf4  heterozygosity  hras1  inbred  inconsistently  involving  loh  murine  neck  nitroquinoline  portion  predispose  scc  strikingly  syntenic  telomeric  thirds  twofold 
aberrantly  acetylglucosaminyltransferase  antigens  bage  ctl  ecto  fig  fm3  fm57  gage  gp100  immunogenic  immunogenicity  in4  maa  mage  mart  melan  melanocyte  melanomas  p15  pbl  permitted  pointing  prame  ref  tab  trp  tyrosinase  uncloned 
Tagcloud (Intersection) ?