CDK4 and CDKN2A

  • Number of citations of the paper that reports this interaction (PMID 15232106)
  • 88
  • Data Source:
  • HPRD (in vivo, in vitro)

CDK4

CDKN2A

Gene Name cyclin-dependent kinase 4 cyclin-dependent kinase inhibitor 2A
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Celiac disease and Rheumatoid arthritis ( 21383967)
Protein-Protein Interactions 90 interactors: ANKRD12 ANXA7 APLP1 APP ARID4A ATP5B BAG6 BCL11A BIRC5 BMPR1B BRCA1 CAMK1 CAPNS1 CCND1 CCND2 CCND3 CDC37 CDC45 CDC6 CDC7 CDKN1A CDKN1B CDKN1C CDKN2A CDKN2B CDKN2C CDKN2D CEBPA CIB1 CNOT7 DAZAP2 DDAH2 DUSP9 FOXM1 GLI1 H1F0 HIST1H1A HIST1H1D HMGXB3 HOOK1 IFI27 IL15RA LUC7L2 MAPRE2 MARCKS MCM2 MYC MYOD1 MZF1 NCOA2 NOL12 ORC3 OTX2 PGD PKM POLD1 PPP2R1B PRKAR1A PSMD10 PTMA QARS RB1 RBL1 RBL2 RFC1 RFC4 RPL34 SENP3 SERTAD1 SETDB1 SHOX2 SKP1 SLBP SMAD2 SMAD3 SNCA TGFBR1 TK1 TRMT2A TSPYL2 UBTF UHRF2 VTA1 WDR33 ZBTB16 ZNF101 ZNF219 ZNF335 ZNF655 ZSCAN1 94 interactors: ACLY ACTB ACTG1 ACTN4 AHNAK ANKRD12 ARFIP2 BCL2L1 BECN1 CARF CCDC183 CCND1 CCND2 CCNG1 CDC45 CDC5L CDC6 CDC7 CDK4 CDK6 CDKN2AIP CDKN2C CRELD2 CTBP2 DEAF1 E2F1 E4F1 EEF2 EGR1 EPHA3 FN1 GAPDH GGA1 GGA3 GMNN GSPT1 HIF1A HIST3H2BB HNRNPA2B1 HNRNPC HNRNPU HSP90AA1 HSP90AB1 HSPA4 HSPA8 HUWE1 KAT5 MAPK10 MAPK8 MCM10 MCM2 MCM5 MCM6 MDM2 MMRN1 MTR MYC MYL12A NCL NMI ORC4 PCNA PDCD6 PEX19 PLEKHA8 PPP1R9B PRKCA PSMC3 RIN2 RPS7 RUVBL2 SERTAD1 SIVA1 SLC4A1 SMARCA4 SNRPA SNRPB TBRG1 TDRD7 TP63 TPI1 TRIP12 TUBA1A TUBA1C TUBB TUBB4B UBE2A UBE4B USP26 WRN YY1 ZFP91 ZNF227 ZNF410
Entrez ID 1019 1029
HPRD ID 00447 02542
Ensembl ID ENSG00000135446 ENSG00000147889
Uniprot IDs P11802 Q6LC83 G3XAG3 K7PML8 P42771 Q8N726
PDB IDs 1LD2 2W96 2W99 2W9F 2W9Z 3G33 1A5E 1BI7 1DC2 2A5E
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aberrantly  acetylglucosaminyltransferase  antigens  bage  ctl  ecto  fig  fm3  fm57  gage  gp100  immunogenic  immunogenicity  in4  maa  mage  mart  melan  melanocyte  melanomas  p15  pbl  permitted  pointing  prame  ref  tab  trp  tyrosinase  uncloned 
a134c  abp  allelic  ankyrin  balb  cdk6  cdnas  chr  congenic  d2  dba  g232a  ifna  inbred  inefficient  ink4c  le  multigenic  mus  p15  p16  p18  pctr1  plasmacytoma  pristane  spretus  typed 
Tagcloud (Difference) ?
aberrantly  acetylglucosaminyltransferase  antigens  bage  ctl  ecto  fig  fm3  fm57  gage  gp100  immunogenic  immunogenicity  in4  maa  mage  mart  melan  melanocyte  melanomas  pbl  permitted  pointing  prame  ref  tab  trp  tyrosinase  uncloned 
a134c  abp  allelic  ankyrin  balb  cdk6  cdnas  chr  congenic  d2  dba  g232a  ifna  inbred  inefficient  ink4c  le  multigenic  mus  p16  p18  pctr1  plasmacytoma  pristane  spretus  typed 
Tagcloud (Intersection) ?
p15