RB1 and CDK6

  • Number of citations of the paper that reports this interaction (PMID 14627988)
  • 10
  • Data Source:
  • HPRD (in vitro)

RB1

CDK6

Gene Name retinoblastoma 1 cyclin-dependent kinase 6
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 167 interactors: AATF ABL1 AHR AR ARID3B ATF2 BAG1 BDP1 BNC2 BRCA1 BRF1 CASP10 CASP2 CASP3 CASP6 CASP7 CASP8 CASP9 CBX1 CBX4 CCNA1 CCNA2 CCNB1 CCNC CCND1 CCND2 CCND3 CCNE1 CCNT2 CDC27 CDK1 CDK14 CDK2 CDK3 CDK4 CDK5 CDK6 CDK9 CDKN1A CDKN1C CEBPA CEBPB CEBPD CEBPE CHEK1 CREG1 CTBP1 CUX1 DGKZ DNMT1 DNMT3A DYRK1A E2F1 E2F2 E2F3 E2F4 E4F1 EID1 ELF1 ENC1 EP300 FOS FRK GNB2L1 GTF3C2 HBP1 HDAC1 HDAC3 HIF1A HMGA2 HMGB1 HSPA8 ID2 INS IRF3 JUN KAT2B KAT5 KDM4A KDM5A KDM5B L3MBTL1 LIN54 LIN9 LMNA MAPK1 MAPK9 MCM7 MDM2 MDM4 MNAT1 MNDA MORF4L1 MORF4L2 MRPS18B MYC MYOD1 NCOA6 NDC80 NEFM PA2G4 PAX2 PAX5 PAX6 PELP1 PHB PIK3R1 PIK3R3 PLA2G12A PML POLA1 PPARG PPIA PPP1CA PPP1CB PPP1CC PRDM2 PRKCB PRKRA PRMT2 PSMD10 PURA RAF1 RBAK RBBP4 RBBP5 RBBP7 RBBP8 RBBP9 RING1 RINT1 RNF40 RUNX2 SERPINB2 SKP2 SMARCA4 SMARCB1 SMYD2 SNAPC1 SNAPC3 SNW1 SP1 SP3 SPI1 SPIB STAT3 SUMO1 SUMO2 SUV39H1 SUV420H2 TAF1 TBP TFAP2A TGM2 THOC1 TMPO TOP2A TRAP1 TRIM27 TRIP11 UBE2I UBTF UHRF2 USP4 USP7 VDR ZBTB16 92 interactors: ABI2 ANKRD12 AR ATF6B ATXN1 BCL11A CASC3 CBY1 CCND1 CCND3 CDC37 CDC6 CDK7 CDKN1A CDKN2A CDKN2B CDKN2C CDKN2D CLASRP CNOT7 CTNNB1 DAB1 DDIT3 DEDD2 EBF4 EIF4ENIF1 ELK1 EZH2 FOXM1 FOXO3 HIST1H1A HSF1 ISL1 KIF26B KLF10 LPIN1 MCM10 MCM2 MEF2D MLLT3 MSL3 MYC MZF1 N4BP1 NFATC3 NIPBL NUMA1 PCNA PML POGZ PPARGC1A PPHLN1 PPM1B PPP2CA PRX PSMA3 RB1 RBL1 RBL2 RBM23 RUNX1 SENP3 SIRT1 SLBP SNIP1 SORBS1 SOX10 SOX5 SRSF1 SRSF11 SRSF12 SRSF2 SRSF7 SSBP2 SYNPO2 TCEB3B TFDP1 TGFBR1 TJP2 TPX2 TRA2A TRA2B TRAK1 UHRF2 VGLL4 ZEB1 ZFP36 ZMYM3 ZNF101 ZNF174 ZNF335 ZSCAN1
Entrez ID 5925 1021
HPRD ID 01574 04533
Ensembl ID ENSG00000139687 ENSG00000105810
Uniprot IDs P06400 A4D1G0 Q00534
PDB IDs 1AD6 1GH6 1GUX 1H25 1N4M 1O9K 1PJM 2AZE 2QDJ 2R7G 3N5U 3POM 4ELJ 4ELL 1BI7 1BI8 1BLX 1G3N 1JOW 1XO2 2EUF 2F2C 3NUP 3NUX 4AUA 4EZ5
Enriched GO Terms of Interacting Partners?
Tagcloud ?
13q14  16q22  18q21  1p35  22p  22q  3p22  5q21  8p  9p21  apc  cent  crc  crcs  dcc  dukes  existed  frequencies  heterozygosity  loh  microsatellite  pairwise  q14  q22  rer  sporadic  ucacrc  ucacrcs  ulcerative 
a134c  abp  allelic  ankyrin  balb  cdkn2a  cdkn2b  cdkn2c  cdnas  chr  congenic  d2  dba  g232a  ifna  inbred  inefficient  ink4c  le  multigenic  mus  p15  p16  p18  pctr1  plasmacytoma  pristane  spretus  typed 
Tagcloud (Difference) ?
13q14  16q22  18q21  1p35  22p  22q  3p22  5q21  8p  9p21  apc  cent  crc  crcs  dcc  dukes  existed  frequencies  heterozygosity  loh  microsatellite  pairwise  q14  q22  rer  sporadic  ucacrc  ucacrcs  ulcerative 
a134c  abp  allelic  ankyrin  balb  cdkn2a  cdkn2b  cdkn2c  cdnas  chr  congenic  d2  dba  g232a  ifna  inbred  inefficient  ink4c  le  multigenic  mus  p15  p16  p18  pctr1  plasmacytoma  pristane  spretus  typed 
Tagcloud (Intersection) ?