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RALGDS and CNKSR1
Number of citations of the paper that reports this interaction (PMID
14749388
)
16
Data Source:
HPRD
(in vivo)
RALGDS
CNKSR1
Gene Name
ral guanine nucleotide dissociation stimulator
connector enhancer of kinase suppressor of Ras 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Brush Border
Plasma Membrane
Cell-cell Junction
Cell Cortex
Molecular Function
Small GTPase Regulator Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Protein Binding, Bridging
Biological Process
Ras Protein Signal Transduction
Positive Regulation Of GTPase Activity
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Catalytic Activity
Regulation Of Small GTPase Mediated Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Ras Protein Signal Transduction
Rho Protein Signal Transduction
Pathways
Signalling to ERKs
Signalling by NGF
Signalling to RAS
p38MAPK events
NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions
23 interactors:
ARRB1
ARRB2
CD68
CNKSR1
HRAS
KRAS
LRPAP1
MAPK3
MLLT4
MRAS
NF2
PDPK1
RAP1A
RAP1B
RAP1GAP
RAP2A
RAP2B
RAPGEF2
RIN1
RIT1
RIT2
RRAS
RRAS2
18 interactors:
ARHGEF1
BRAP
CADM4
CYTH3
CYTH4
MAP2K2
MAP2K7
MAP3K10
PIN1
RAF1
RALGDS
RASSF1
RHOA
RHPN1
SMAD4
STK3
STK4
ZDHHC17
Entrez ID
5900
10256
HPRD ID
03371
11937
Ensembl ID
ENSG00000160271
ENSG00000142675
Uniprot IDs
B7Z753
E7ER93
E7ERZ0
Q12967
Q6PCE1
Q6ZSD5
Q8N4Y1
Q53GM7
Q969H4
PDB IDs
1RAX
2B3A
2RGF
3KH0
1WWV
Enriched GO Terms of Interacting Partners
?
Ras Protein Signal Transduction
Small GTPase Mediated Signal Transduction
Rap Protein Signal Transduction
Neurotrophin Signaling Pathway
Positive Regulation Of Rap GTPase Activity
Regulation Of MAPK Cascade
Regulation Of ERK1 And ERK2 Cascade
Intracellular Signal Transduction
Regulation Of Rap GTPase Activity
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Protein Phosphorylation
Regulation Of Rap Protein Signal Transduction
Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Regulation Of Intracellular Signal Transduction
Cellular Response To Growth Factor Stimulus
Signal Transduction
Response To Growth Factor
Positive Regulation Of Phosphorylation
Blood Coagulation
Regulation Of Phosphorus Metabolic Process
Hemostasis
Positive Regulation Of Protein Modification Process
Signaling
Cellular Response To Stimulus
Cell Communication
Platelet Activation
Regulation Of Signaling
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Wound Healing
Regulation Of Catalytic Activity
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of MAPK Cascade
Positive Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Synaptic Transmission
Response To Wounding
Regulation Of Protein Kinase Activity
Establishment Of Endothelial Barrier
Response To Stimulus
Regulation Of GTPase Activity
Regulation Of Kinase Activity
Positive Regulation Of Metabolic Process
Epithelial Cell Development
Regulation Of Cell Migration
Positive Regulation Of Catalytic Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Signal Transduction
Regulation Of Signaling
Ras Protein Signal Transduction
Regulation Of Intracellular Signal Transduction
Intracellular Signal Transduction
Signal Transduction By Phosphorylation
Positive Regulation Of Catalytic Activity
Positive Regulation Of Protein Modification Process
Regulation Of Catalytic Activity
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Metabolic Process
Signal Transduction
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Phosphorylation
Positive Regulation Of Transferase Activity
Positive Regulation Of Signal Transduction
Signaling
Endocardium Development
Small GTPase Mediated Signal Transduction
Cell Communication
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Protein Phosphorylation
Neurotrophin Signaling Pathway
MAPK Cascade
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Kinase Activity
Positive Regulation Of Intracellular Signal Transduction
Cellular Response To Stimulus
Positive Regulation Of Protein Serine/threonine Kinase Activity
Regulation Of Phosphorylation
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Regulation Of MAPK Cascade
Regulation Of Cellular Protein Metabolic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Protein Metabolic Process
Regulation Of Stress-activated MAPK Cascade
Regulation Of Protein Kinase Activity
Activation Of MAPKK Activity
Positive Regulation Of MAPK Cascade
Regulation Of Kinase Activity
Protein Autophosphorylation
Primitive Hemopoiesis
Response To Stimulus
Cellular Response To Organic Substance
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Tagcloud
?
abi1
atlas
bitbucket
ccnd3
ctnnd1
doi
driver
drivers
dx
fbln2
figshare
hindered
http
https
identifies
implies
isoform
ktsp
m9
mitf
myh11
org
pparg
prdm1
regulatorygenomicsupf
signatures
splicing
switches
transcript
Tagcloud (Difference)
?
abi1
atlas
bitbucket
ccnd3
ctnnd1
doi
driver
drivers
dx
fbln2
figshare
hindered
http
https
identifies
implies
isoform
ktsp
m9
mitf
myh11
org
pparg
prdm1
regulatorygenomicsupf
signatures
splicing
switches
transcript
Tagcloud (Intersection)
?