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RALGDS
Gene Name
ral guanine nucleotide dissociation stimulator
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Brush Border
Molecular Function
Small GTPase Regulator Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Biological Process
Ras Protein Signal Transduction
Positive Regulation Of GTPase Activity
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Catalytic Activity
Regulation Of Small GTPase Mediated Signal Transduction
Pathways
Signalling to ERKs
Signalling by NGF
Signalling to RAS
p38MAPK events
NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Protein-protein Interactions
23 interactors:
ARRB1
ARRB2
CD68
CNKSR1
HRAS
KRAS
LRPAP1
MAPK3
MLLT4
MRAS
NF2
PDPK1
RAP1A
RAP1B
RAP1GAP
RAP2A
RAP2B
RAPGEF2
RIN1
RIT1
RIT2
RRAS
RRAS2
Entrez ID
5900
HPRD ID
03371
Ensembl ID
ENSG00000160271
Uniprot IDs
B7Z753
E7ER93
E7ERZ0
Q12967
Q6PCE1
Q6ZSD5
Q8N4Y1
PDB IDs
1RAX
2B3A
2RGF
3KH0
Enriched GO Terms of Interacting Partners
?
Ras Protein Signal Transduction
Small GTPase Mediated Signal Transduction
Rap Protein Signal Transduction
Neurotrophin Signaling Pathway
Positive Regulation Of Rap GTPase Activity
Regulation Of MAPK Cascade
Regulation Of ERK1 And ERK2 Cascade
Intracellular Signal Transduction
Regulation Of Rap GTPase Activity
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Protein Phosphorylation
Regulation Of Rap Protein Signal Transduction
Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Regulation Of Intracellular Signal Transduction
Cellular Response To Growth Factor Stimulus
Signal Transduction
Response To Growth Factor
Positive Regulation Of Phosphorylation
Blood Coagulation
Regulation Of Phosphorus Metabolic Process
Hemostasis
Positive Regulation Of Protein Modification Process
Signaling
Cellular Response To Stimulus
Cell Communication
Platelet Activation
Regulation Of Signaling
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Wound Healing
Regulation Of Catalytic Activity
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of MAPK Cascade
Positive Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Synaptic Transmission
Response To Wounding
Regulation Of Protein Kinase Activity
Establishment Of Endothelial Barrier
Response To Stimulus
Regulation Of GTPase Activity
Regulation Of Kinase Activity
Positive Regulation Of Metabolic Process
Epithelial Cell Development
Regulation Of Cell Migration
Positive Regulation Of Catalytic Activity
Regulation Of Cellular Protein Metabolic Process
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