CNKSR1 and CYTH4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CNKSR1	CYTH4
Gene Name		connector enhancer of kinase suppressor of Ras 1	cytohesin 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Cell Cortex	Trans-Golgi Network Plasma Membrane
	Molecular Function	Protein Binding, Bridging	ARF Guanyl-nucleotide Exchange Factor Activity Lipid Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ras Protein Signal Transduction Rho Protein Signal Transduction	Vesicle-mediated Transport Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: ARHGEF1 BRAP CADM4 CYTH3 CYTH4 MAP2K2 MAP2K7 MAP3K10 PIN1 RAF1 RALGDS RASSF1 RHOA RHPN1 SMAD4 STK3 STK4 ZDHHC17	9 interactors: AMOTL2 CNKSR1 FOS IPCEF1 KIFC3 KRT15 KRT40 SNAPC5 TRIM54
Entrez ID		10256	27128
HPRD ID		11937	07354
Ensembl ID		ENSG00000142675	ENSG00000100055
Uniprot IDs		Q53GM7 Q969H4	Q9UIA0
PDB IDs		1WWV
Enriched GO Terms of Interacting Partners?		Regulation Of Signal Transduction Regulation Of Signaling Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Signal Transduction By Phosphorylation Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Modification Process Regulation Of Catalytic Activity Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Transferase Activity Positive Regulation Of Signal Transduction Signaling Endocardium Development Small GTPase Mediated Signal Transduction Cell Communication Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Phosphorylation Neurotrophin Signaling Pathway MAPK Cascade Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Cellular Response To Stimulus Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of MAPK Cascade Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Protein Metabolic Process Regulation Of Stress-activated MAPK Cascade Regulation Of Protein Kinase Activity Activation Of MAPKK Activity Positive Regulation Of MAPK Cascade Regulation Of Kinase Activity Protein Autophosphorylation Primitive Hemopoiesis Response To Stimulus Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cellular Metabolic Process
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