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RALGDS and LRPAP1
Number of citations of the paper that reports this interaction (PMID
10783161
)
36
Data Source:
BioGRID
(two hybrid)
RALGDS
LRPAP1
Gene Name
ral guanine nucleotide dissociation stimulator
low density lipoprotein receptor-related protein associated protein 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Brush Border
Extracellular Region
Endoplasmic Reticulum
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Vesicle
Rough Endoplasmic Reticulum Lumen
Molecular Function
Small GTPase Regulator Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Asialoglycoprotein Receptor Activity
Protein Binding
Heparin Binding
Lipase Binding
Receptor Antagonist Activity
Low-density Lipoprotein Particle Receptor Binding
Unfolded Protein Binding
Very-low-density Lipoprotein Particle Receptor Binding
Biological Process
Ras Protein Signal Transduction
Positive Regulation Of GTPase Activity
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Catalytic Activity
Regulation Of Small GTPase Mediated Signal Transduction
Protein Folding
Receptor-mediated Endocytosis
Negative Regulation Of Very-low-density Lipoprotein Particle Clearance
Vesicle-mediated Transport
Negative Regulation Of Protein Binding
Extracellular Negative Regulation Of Signal Transduction
Negative Regulation Of Beta-amyloid Clearance
Pathways
Signalling to ERKs
Signalling by NGF
Signalling to RAS
p38MAPK events
NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions
23 interactors:
ARRB1
ARRB2
CD68
CNKSR1
HRAS
KRAS
LRPAP1
MAPK3
MLLT4
MRAS
NF2
PDPK1
RAP1A
RAP1B
RAP1GAP
RAP2A
RAP2B
RAPGEF2
RIN1
RIT1
RIT2
RRAS
RRAS2
18 interactors:
ETV7
LDLR
LRP1
LRP1B
LRP2
LRP8
MAPK1
MAPK3
POLA2
PPM1G
RAF1
RALA
RALGDS
RANBP2
RTN4
SORL1
SORT1
VLDLR
Entrez ID
5900
4043
HPRD ID
03371
00082
Ensembl ID
ENSG00000160271
Uniprot IDs
B7Z753
E7ER93
E7ERZ0
Q12967
Q6PCE1
Q6ZSD5
Q8N4Y1
P30533
PDB IDs
1RAX
2B3A
2RGF
3KH0
1LRE
1NRE
1OP1
1OV2
2FCW
2FTU
2FYL
2P01
2P03
Enriched GO Terms of Interacting Partners
?
Ras Protein Signal Transduction
Small GTPase Mediated Signal Transduction
Rap Protein Signal Transduction
Neurotrophin Signaling Pathway
Positive Regulation Of Rap GTPase Activity
Regulation Of MAPK Cascade
Regulation Of ERK1 And ERK2 Cascade
Intracellular Signal Transduction
Regulation Of Rap GTPase Activity
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Protein Phosphorylation
Regulation Of Rap Protein Signal Transduction
Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Regulation Of Intracellular Signal Transduction
Cellular Response To Growth Factor Stimulus
Signal Transduction
Response To Growth Factor
Positive Regulation Of Phosphorylation
Blood Coagulation
Regulation Of Phosphorus Metabolic Process
Hemostasis
Positive Regulation Of Protein Modification Process
Signaling
Cellular Response To Stimulus
Cell Communication
Platelet Activation
Regulation Of Signaling
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Wound Healing
Regulation Of Catalytic Activity
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of MAPK Cascade
Positive Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Synaptic Transmission
Response To Wounding
Regulation Of Protein Kinase Activity
Establishment Of Endothelial Barrier
Response To Stimulus
Regulation Of GTPase Activity
Regulation Of Kinase Activity
Positive Regulation Of Metabolic Process
Epithelial Cell Development
Regulation Of Cell Migration
Positive Regulation Of Catalytic Activity
Regulation Of Cellular Protein Metabolic Process
Receptor-mediated Endocytosis
Endocytosis
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Vesicle-mediated Transport
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Phototransduction, Visible Light
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Retinoid Metabolic Process
Transport
Ras Protein Signal Transduction
Diterpenoid Metabolic Process
Detection Of Visible Light
Phototransduction
Signal Transduction
Regulation Of Kinase Activity
Steroid Metabolic Process
Detection Of Light Stimulus
Cholesterol Metabolic Process
Signaling
Isoprenoid Metabolic Process
Regulation Of Catalytic Activity
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Transferase Activity
Sterol Metabolic Process
Cell Communication
Cell Surface Receptor Signaling Pathway
Cellular Response To Organic Substance
Regulation Of Golgi Inheritance
Regulation Of Cellular Component Organization
Alcohol Metabolic Process
Caveolin-mediated Endocytosis
Regulation Of Phosphorus Metabolic Process
Detection Of Abiotic Stimulus
Response To Abiotic Stimulus
Reelin-mediated Signaling Pathway
Regulation Of Protein Kinase Activity
Regulation Of Golgi Organization
Cellular Response To Stimulus
Activation Of MAPKK Activity
Positive Regulation Of Protein Kinase Activity
Locomotion
Response To External Stimulus
Positive Regulation Of Kinase Activity
Regulation Of Cellular Ketone Metabolic Process
Regulation Of Phosphorylation
Response To Organic Substance
Regulation Of Early Endosome To Late Endosome Transport
Viral Process
Tagcloud
?
abi1
atlas
bitbucket
ccnd3
ctnnd1
doi
driver
drivers
dx
fbln2
figshare
hindered
http
https
identifies
implies
isoform
ktsp
m9
mitf
myh11
org
pparg
prdm1
regulatorygenomicsupf
signatures
splicing
switches
transcript
Tagcloud (Difference)
?
abi1
atlas
bitbucket
ccnd3
ctnnd1
doi
driver
drivers
dx
fbln2
figshare
hindered
http
https
identifies
implies
isoform
ktsp
m9
mitf
myh11
org
pparg
prdm1
regulatorygenomicsupf
signatures
splicing
switches
transcript
Tagcloud (Intersection)
?