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RALGDS and RRAS2
Number of citations of the paper that reports this interaction (PMID
11788587
)
15
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(in vivo, two hybrid, in vitro)
RALGDS
RRAS2
Gene Name
ral guanine nucleotide dissociation stimulator
related RAS viral (r-ras) oncogene homolog 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Brush Border
Endoplasmic Reticulum
Plasma Membrane
Focal Adhesion
Membrane
Extracellular Vesicular Exosome
Molecular Function
Small GTPase Regulator Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
GTPase Activity
Protein Binding
GTP Binding
Biological Process
Ras Protein Signal Transduction
Positive Regulation Of GTPase Activity
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Catalytic Activity
Regulation Of Small GTPase Mediated Signal Transduction
Osteoblast Differentiation
Ras Protein Signal Transduction
Positive Regulation Of Cell Migration
Regulation Of Neuron Death
Pathways
Signalling to ERKs
Signalling by NGF
Signalling to RAS
p38MAPK events
NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Alzheimer's disease (cognitive decline) (
23535033
)
Protein-Protein Interactions
23 interactors:
ARRB1
ARRB2
CD68
CNKSR1
HRAS
KRAS
LRPAP1
MAPK3
MLLT4
MRAS
NF2
PDPK1
RAP1A
RAP1B
RAP1GAP
RAP2A
RAP2B
RAPGEF2
RIN1
RIT1
RIT2
RRAS
RRAS2
29 interactors:
ACVR1
AHSG
ARAF
ARHGEF2
BMPR1B
CREB3
FNTB
LGALS4
MLLT4
PAWR
PGGT1B
PIK3R1
PTPN1
RABAC1
RAF1
RALGDS
RAPGEF1
RAPGEF3
RAPGEF4
RASGRF1
RASIP1
RASSF5
RIN1
SMAD3
SMAD4
SMURF2
TRAF2
TRAF3
XRCC6
Entrez ID
5900
22800
HPRD ID
03371
02518
Ensembl ID
ENSG00000160271
ENSG00000133818
Uniprot IDs
B7Z753
E7ER93
E7ERZ0
Q12967
Q6PCE1
Q6ZSD5
Q8N4Y1
B7Z5Z2
P62070
PDB IDs
1RAX
2B3A
2RGF
3KH0
2ERY
Enriched GO Terms of Interacting Partners
?
Ras Protein Signal Transduction
Small GTPase Mediated Signal Transduction
Rap Protein Signal Transduction
Neurotrophin Signaling Pathway
Positive Regulation Of Rap GTPase Activity
Regulation Of MAPK Cascade
Regulation Of ERK1 And ERK2 Cascade
Intracellular Signal Transduction
Regulation Of Rap GTPase Activity
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Protein Phosphorylation
Regulation Of Rap Protein Signal Transduction
Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Regulation Of Intracellular Signal Transduction
Cellular Response To Growth Factor Stimulus
Signal Transduction
Response To Growth Factor
Positive Regulation Of Phosphorylation
Blood Coagulation
Regulation Of Phosphorus Metabolic Process
Hemostasis
Positive Regulation Of Protein Modification Process
Signaling
Cellular Response To Stimulus
Cell Communication
Platelet Activation
Regulation Of Signaling
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Wound Healing
Regulation Of Catalytic Activity
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of MAPK Cascade
Positive Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Synaptic Transmission
Response To Wounding
Regulation Of Protein Kinase Activity
Establishment Of Endothelial Barrier
Response To Stimulus
Regulation Of GTPase Activity
Regulation Of Kinase Activity
Positive Regulation Of Metabolic Process
Epithelial Cell Development
Regulation Of Cell Migration
Positive Regulation Of Catalytic Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Signaling
Regulation Of Signal Transduction
Regulation Of Metabolic Process
Signal Transduction
Response To Stimulus
Signaling
Cell Communication
Positive Regulation Of Metabolic Process
Cellular Response To Stimulus
Intracellular Signal Transduction
Regulation Of Phosphorylation
Regulation Of Catalytic Activity
Response To Organic Substance
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Metabolic Process
Cellular Response To Organic Substance
Positive Regulation Of Hydrolase Activity
Cellular Response To Growth Factor Stimulus
Regulation Of Protein Phosphorylation
Response To Growth Factor
Regulation Of Intracellular Signal Transduction
Endothelial Cell Differentiation
Positive Regulation Of Catalytic Activity
Regulation Of Cell Death
Endothelium Development
Regulation Of Cellular Protein Metabolic Process
Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Cellular Process
Regulation Of GTPase Activity
Response To Stress
Negative Regulation Of Signal Transduction
Positive Regulation Of Cellular Metabolic Process
Regulation Of Apoptotic Process
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Proliferation
Negative Regulation Of Signaling
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Cell Proliferation
Positive Regulation Of Signal Transduction
Negative Regulation Of Cell Death
Positive Regulation Of Rap GTPase Activity
Positive Regulation Of GTPase Activity
Regulation Of Bone Mineralization
Defense Response
BMP Signaling Pathway
Regulation Of Cytokine Production
Regulation Of Ras GTPase Activity
Regulation Of Protein Localization
Tagcloud
?
abi1
atlas
bitbucket
ccnd3
ctnnd1
doi
driver
drivers
dx
fbln2
figshare
hindered
http
https
identifies
implies
isoform
ktsp
m9
mitf
myh11
org
pparg
prdm1
regulatorygenomicsupf
signatures
splicing
switches
transcript
Tagcloud (Difference)
?
abi1
atlas
bitbucket
ccnd3
ctnnd1
doi
driver
drivers
dx
fbln2
figshare
hindered
http
https
identifies
implies
isoform
ktsp
m9
mitf
myh11
org
pparg
prdm1
regulatorygenomicsupf
signatures
splicing
switches
transcript
Tagcloud (Intersection)
?