PXN and PKD1

  • Number of citations of the paper that reports this interaction (PMID 11113628)
  • 23
  • Data Source:
  • HPRD (in vitro, in vivo)

PXN

PKD1

Gene Name paxillin polycystic kidney disease 1 (autosomal dominant)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 73 interactors: ABL1 AHCY AR ARHGEF7 ASAP1 ASAP2 BCAR1 BCL2 CASP3 CEACAM1 CLTC CREB3L2 CRK CRKL CSK DGUOK EPHB1 FYN GART GIT1 GIT2 GRB2 GSK3A GSK3B GSN HDAC6 ILK ITGA4 ITGA6 ITGA9 ITGB1 ITGB3 LCK LIMK1 MAPK1 MAPK3 MAPK8 MATK NCK1 NEDD9 NF2 PABPC1 PAK1 PAK3 PARVA PDPK1 PKD1 POLR1D PPP2CA PPP2R5C PTEN PTK2 PTK2B PTPN11 PTPN12 PTPRH RASA1 REPS2 RNF5 SDC4 SELE SORBS1 SRC SYK TLN1 TRIP6 TUBA1B TUBA3C TUBA8 TUBG1 TUBG2 VCL XPO1 25 interactors: ACTN1 ATF7IP BCAR1 CDH1 COL1A1 COL2A1 CTNNA1 CTNNB1 DES FN1 HDAC9 JAK2 JUP KRT18 KRT8 MARK2 PKD2 PTK2 PXN RGS7 SIAH1 SRC TLN1 VCL VIM
Entrez ID 5829 5310
HPRD ID 03937 03203
Ensembl ID ENSG00000089159 ENSG00000008710
Uniprot IDs E7EMK8 F5GZ78 P49023 P98161
PDB IDs 1KKY 1KL0 1OW6 1OW7 1OW8 2K2R 2O9V 2VZD 2VZG 2VZI 3GM1 3PY7 3RQE 3RQF 3RQG 3U3C 3U3F 4EDN 1B4R
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acclimatized  adra1d  altitude  araf  argef11  arhgap24  ascent  cardiogenic  circuitry  cldn23  cldn6  ece1  ednra  genic  hape  inciting  map2k2  map2k7  mapk10  mylk  oxphos  pak3  pathoetiology  plcb1  skew  sos1  unacclimatized  vasoconstriction  vcam1 
acts  adpkd  autosomal  chaperone  coil  coiled  complexing  determinant  disrupted  distal  glycoform  gps  heterozygotes  illustrating  inherited  interbreeding  maturation  mature  missense  nephropathy  nonequimolar  pathogenic  pc1  pc2  pkd2  polycystic  polycystin  progressive  severity 
Tagcloud (Difference) ?
acclimatized  adra1d  altitude  araf  argef11  arhgap24  ascent  cardiogenic  circuitry  cldn23  cldn6  ece1  ednra  genic  hape  inciting  map2k2  map2k7  mapk10  mylk  oxphos  pak3  pathoetiology  plcb1  skew  sos1  unacclimatized  vasoconstriction  vcam1 
acts  adpkd  autosomal  chaperone  coil  coiled  complexing  determinant  disrupted  distal  glycoform  gps  heterozygotes  illustrating  inherited  interbreeding  maturation  mature  missense  nephropathy  nonequimolar  pathogenic  pc1  pc2  pkd2  polycystic  polycystin  progressive  severity 
Tagcloud (Intersection) ?