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PKD1 and CTNNA1
Number of citations of the paper that reports this interaction (PubMedID
11274246
)
0
Data Source:
HPRD
(in vitro, in vivo)
PKD1
CTNNA1
Description
polycystin 1, transient receptor potential channel interacting
catenin alpha 1
Image
GO Annotations
Cellular Component
Golgi Membrane
Polycystin Complex
Extracellular Region
Nucleus
Cytoplasm
Endoplasmic Reticulum
Golgi Apparatus
Plasma Membrane
Cilium
Cell Surface
Membrane
Basolateral Plasma Membrane
Lateral Plasma Membrane
Golgi-associated Vesicle Membrane
Motile Cilium
Vesicle
Cation Channel Complex
Calcium Channel Complex
Cell Projection
Ciliary Membrane
Extracellular Exosome
Migrasome
Acrosomal Vesicle
Nucleus
Cytoplasm
Golgi Apparatus
Cytosol
Cytoskeleton
Plasma Membrane
Cell-cell Junction
Adherens Junction
Zonula Adherens
Focal Adhesion
Intercalated Disc
Actin Cytoskeleton
Membrane
Catenin Complex
Flotillin Complex
Lamellipodium
Cell Junction
Anchoring Junction
Plasma Membrane Protein Complex
Molecular Function
Monoatomic Cation Channel Activity
Calcium Channel Activity
Protein Binding
Protein Kinase Binding
Protein Domain Specific Binding
Carbohydrate Binding
Wnt Receptor Activity
Transmembrane Transporter Binding
Transcription Regulator Inhibitor Activity
RNA Binding
Structural Molecule Activity
Protein Binding
Beta-catenin Binding
Cytoskeletal Protein Binding
Vinculin Binding
Identical Protein Binding
Protein-containing Complex Binding
Gamma-catenin Binding
Cadherin Binding
Actin Filament Binding
Biological Process
Cartilage Condensation
Blood Vessel Development
In Utero Embryonic Development
Kidney Development
Liver Development
Embryonic Placenta Development
Protein Export From Nucleus
Calcium Ion Transport
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Cell-matrix Adhesion
Calcium-independent Cell-matrix Adhesion
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Heart Development
Anatomical Structure Morphogenesis
Animal Organ Morphogenesis
Regulation Of Gene Expression
Regulation Of Cell Cycle Process
Wnt Signaling Pathway
Spinal Cord Development
Neural Tube Development
Establishment Of Cell Polarity
Regulation Of Cell Adhesion
Response To Fluid Shear Stress
Lymph Vessel Morphogenesis
Chordate Embryonic Development
Skin Development
Positive Regulation Of Transcription By RNA Polymerase II
Digestive Tract Development
Branching Morphogenesis Of An Epithelial Tube
Genitalia Development
Detection Of Mechanical Stimulus
Cartilage Development
Protein Heterotetramerization
Regulation Of Cell Cycle
Regulation Of Mitotic Spindle Organization
Lung Epithelium Development
Placenta Blood Vessel Development
Regulation Of Proteasomal Protein Catabolic Process
Calcium Ion Transmembrane Transport
Nitrogen Cycle Metabolic Process
Mesonephric Tubule Development
Mesonephric Duct Development
Metanephric Collecting Duct Development
Metanephric Ascending Thin Limb Development
Metanephric Proximal Tubule Development
Metanephric Distal Tubule Morphogenesis
Cell-cell Adhesion
Mitocytosis
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Ovarian Follicle Development
Apoptotic Process
Cell Adhesion
Establishment Or Maintenance Of Cell Polarity
Smoothened Signaling Pathway
Integrin-mediated Signaling Pathway
Neuroblast Proliferation
Negative Regulation Of Neuroblast Proliferation
Intracellular Protein Localization
Male Gonad Development
Gap Junction Assembly
Cell Migration
Axon Regeneration
Regulation Of Cell Population Proliferation
Odontogenesis Of Dentin-containing Tooth
Negative Regulation Of Apoptotic Process
Apical Junction Assembly
Response To Estrogen
Positive Regulation Of Smoothened Signaling Pathway
Cell Motility
Cellular Response To Indole-3-methanol
Epithelial Cell-cell Adhesion
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Cell-cell Adhesion
Negative Regulation Of Protein Localization To Nucleus
Negative Regulation Of Cell Motility
Negative Regulation Of Integrin-mediated Signaling Pathway
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
VxPx cargo-targeting to cilium
VxPx cargo-targeting to cilium
Adherens junctions interactions
VEGFR2 mediated vascular permeability
Myogenesis
Myogenesis
RHO GTPases activate IQGAPs
Regulation of CDH11 function
Regulation of CDH19 Expression and Function
Regulation of CDH1 Function
Degradation of CDH1
CDH11 homotypic and heterotypic interactions
Drugs
Diseases
Polycystic kidney disease
GWAS
Appendicular lean mass (
33097823
)
Dilated cardiomyopathy (
33677556
)
Estimated glomerular filtration rate (
31451708
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Heel bone mineral density (
30598549
)
Height (
28552196
)
High light scatter reticulocyte count (
32888494
)
Hypertrophic cardiomyopathy (MTAG) (
33495596
)
Low hand grip strength (60 years and older) (EWGSOP) (
33510174
)
Major depressive disorder (
29317602
)
Neutrophil count (
32888494
)
Systolic blood pressure (
30578418
)
Waist circumference adjusted for body mass index (
34021172
)
Femur bone mineral density x serum urate levels interaction (
34046847
)
General risk tolerance (MTAG) (
30643258
)
Malaria (
31844061
)
Schizophrenia (
25056061
)
Interacting Genes
31 interacting genes:
ACTN1
ATF7IP
BCAR1
CDH1
COL1A1
COL2A1
CTNNA1
CTNNB1
DES
FN1
HDAC9
JAK2
JUP
KRT18
KRT8
LTB4R2
MARK2
NCF1
NCK2
PIP5K1C
PKD2
PTK2
PTPRG
PXN
RGS7
RUNX1
SIAH1
SRC
TLN1
VCL
VIM
55 interacting genes:
ACTN1
AFDN
AJUBA
AKT1
ALDOB
APP
ARMC8
BAAT
CA9
CCDC180
CDC42
CDH1
CDH15
CDH2
CDH3
CDH5
CSNK2A1
CTBP1
CTNNB1
CTSV
DLG1
DYRK1A
EIF4ENIF1
F2RL1
FBP1
FBP2
FRAT2
HRAS
HSD17B3
HSPA13
JUP
LRATD2
MAP2K1
MTNR1A
MTNR1B
NANS
PKD1
PSEN1
RBM26
RNF10
SASH1
SFRP2
SFRP4
SMAD1
SPTAN1
SPTBN1
STX17
TDRD7
TJP1
TJP2
UBE2I
VCL
ZGPAT
ZNF189
ZNF510
Entrez ID
5310
1495
HPRD ID
03203
00285
Ensembl ID
ENSG00000008710
ENSG00000044115
Uniprot IDs
P98161
A0A384MDY0
B4DKT9
B4DU00
G3XAM7
P35221
PDB IDs
1B4R
6A70
1H6G
4EHP
4IGG
6UPV
6V2O
6V2P
7UTJ
9BL2
9BL3
9BL4
Enriched GO Terms of Interacting Partners
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Anchoring Junction
Focal Adhesion
Cell-cell Junction
Cellular Response To Indole-3-methanol
Cell Junction Assembly
Response To Indole-3-methanol
Cell Surface Receptor Signaling Pathway
Cell Migration
Fascia Adherens
Regulation Of Cell Adhesion
Signal Complex Assembly
Cell Adhesion
Cell Motility
Epidermal Growth Factor Receptor Signaling Pathway
Adherens Junction
Vinculin Binding
Cell-cell Junction Assembly
ERBB Signaling Pathway
Regulation Of Cell Motility
Cadherin Binding
Regulation Of Cell-substrate Adhesion
Cellular Response To Oxygen-containing Compound
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Locomotion
Cell Junction Organization
Integrin-mediated Signaling Pathway
Cell-cell Junction Organization
Regulation Of Cell Migration
Extrinsic Apoptotic Signaling Pathway
Plasma Membrane
Plasma Membrane Bounded Cell Projection Organization
Cytoskeleton
Catenin Complex
Signal Transduction
Zonula Adherens
Scaffold Protein Binding
Flotillin Complex
Cellular Response To Fluid Shear Stress
Neuron Projection Development
Alpha-catenin Binding
Supramolecular Fiber Organization
Cell-cell Adhesion
Intermediate Filament
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of Cell-cell Adhesion
Cell-substrate Junction Assembly
Cell-substrate Junction Organization
Cytoplasm
Anatomical Structure Morphogenesis
Response To Fluid Shear Stress
Cell-cell Junction Organization
Cell Junction Organization
Adherens Junction
Cadherin Binding
Adherens Junction Organization
Cell Junction Assembly
Cell-cell Junction Assembly
Cell Junction
Cell-cell Adhesion
Catenin Complex
Cell-cell Junction
Cell-cell Adhesion Mediated By Cadherin
Alpha-catenin Binding
Anchoring Junction
Cell Adhesion
Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Fascia Adherens
Anatomical Structure Morphogenesis
Regulation Of Cell Motility
Regulation Of Protein Localization
Glutamatergic Synapse
Regulation Of Locomotion
Beta-catenin Binding
Regulation Of Cell Migration
Positive Regulation Of Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Cellular Component Organization
Plasma Membrane
Cellular Response To Indole-3-methanol
Regulation Of Supramolecular Fiber Organization
Cell Development
Regulation Of Cell Population Proliferation
Response To Indole-3-methanol
Cytoplasm
Cortical Actin Cytoskeleton
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Wnt Signaling Pathway
Positive Regulation Of Gene Expression
Regulation Of DNA-templated Transcription
Developmental Process
Regulation Of RNA Biosynthetic Process
Regulation Of Cell Adhesion
Negative Regulation Of Signal Transduction
Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Multicellular Organismal Development
Positive Regulation Of Angiogenesis
Positive Regulation Of Macromolecule Biosynthetic Process
Protein Kinase Binding
Fructose 1,6-bisphosphate Metabolic Process
Regulation Of RNA Metabolic Process
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Tagcloud (Difference)
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Tagcloud (Intersection)
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