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PXN and CREB3L2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
PXN
CREB3L2
Gene Name
paxillin
cAMP responsive element binding protein 3-like 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Stress Fiber
Nucleoplasm
Cytoplasm
Cytosol
Microtubule Associated Complex
Plasma Membrane
Focal Adhesion
Cell Cortex
Lamellipodium
Nucleus
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Molecular Function
Integrin Binding
Protein Binding
Beta-catenin Binding
Zinc Ion Binding
Vinculin Binding
Protein Kinase Binding
BH4 Domain Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
CAMP Response Element Binding
Transcription Regulatory Region DNA Binding
Biological Process
Activation Of MAPK Activity
Movement Of Cell Or Subcellular Component
Muscle Contraction
Cytoskeleton Organization
Cell Adhesion
Signal Transduction
Signal Complex Assembly
Epidermal Growth Factor Receptor Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Regulation Of Cell Shape
Peptidyl-tyrosine Phosphorylation
Lamellipodium Assembly
Cell Junction Assembly
Substrate Adhesion-dependent Cell Spreading
Cellular Response To Reactive Oxygen Species
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Focal Adhesion Assembly
Branching Morphogenesis Of An Epithelial Tube
Growth Hormone Receptor Signaling Pathway
Chondrocyte Differentiation
Transcription, DNA-templated
ER To Golgi Vesicle-mediated Transport
Endoplasmic Reticulum Unfolded Protein Response
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cartilage Development
Pathways
Cell junction organization
GAB1 signalosome
Smooth Muscle Contraction
Signaling by Ligand-Responsive EGFR Variants in Cancer
Signaling by EGFRvIII in Cancer
Signaling by Overexpressed Wild-Type EGFR in Cancer
VEGFA-VEGFR2 Pathway
Signaling by EGFR
Signaling by VEGF
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Signaling by EGFR in Cancer
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions
73 interactors:
ABL1
AHCY
AR
ARHGEF7
ASAP1
ASAP2
BCAR1
BCL2
CASP3
CEACAM1
CLTC
CREB3L2
CRK
CRKL
CSK
DGUOK
EPHB1
FYN
GART
GIT1
GIT2
GRB2
GSK3A
GSK3B
GSN
HDAC6
ILK
ITGA4
ITGA6
ITGA9
ITGB1
ITGB3
LCK
LIMK1
MAPK1
MAPK3
MAPK8
MATK
NCK1
NEDD9
NF2
PABPC1
PAK1
PAK3
PARVA
PDPK1
PKD1
POLR1D
PPP2CA
PPP2R5C
PTEN
PTK2
PTK2B
PTPN11
PTPN12
PTPRH
RASA1
REPS2
RNF5
SDC4
SELE
SORBS1
SRC
SYK
TLN1
TRIP6
TUBA1B
TUBA3C
TUBA8
TUBG1
TUBG2
VCL
XPO1
12 interactors:
CEP19
FBXW7
GAS7
GCFC2
GULP1
PTP4A1
PXN
RGS16
RND1
UBA1
UBE2D3
ZNF212
Entrez ID
5829
64764
HPRD ID
03937
16391
Ensembl ID
ENSG00000089159
ENSG00000182158
Uniprot IDs
E7EMK8
F5GZ78
P49023
Q68D60
Q70SY1
PDB IDs
1KKY
1KL0
1OW6
1OW7
1OW8
2K2R
2O9V
2VZD
2VZG
2VZI
3GM1
3PY7
3RQE
3RQF
3RQG
3U3C
3U3F
4EDN
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Cellular Component Organization
Locomotion
Movement Of Cell Or Subcellular Component
Regulation Of Cell Adhesion
Cell Morphogenesis Involved In Differentiation
Response To Wounding
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Wound Healing
Blood Coagulation
Regulation Of Phosphorylation
Hemostasis
Cell Migration
Response To External Stimulus
Cell Projection Morphogenesis
Axonogenesis
Cell Part Morphogenesis
Cell Morphogenesis
Immune System Process
Immune Response-regulating Signaling Pathway
Neuron Projection Morphogenesis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell Motility
Positive Regulation Of Catalytic Activity
Axon Development
Anatomical Structure Morphogenesis
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Signal Transduction
Regulation Of Protein Kinase Activity
Cell Surface Receptor Signaling Pathway
Cell Projection Organization
Regulation Of Phosphorus Metabolic Process
Regulation Of Intracellular Signal Transduction
Fc Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Axon Guidance
Positive Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Chemotaxis
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Neuron Projection Development
Response To Stress
Positive Regulation Of Protein Phosphorylation
Signal Transduction
Cell-substrate Adhesion
Tagcloud
?
acclimatized
adra1d
altitude
araf
argef11
arhgap24
ascent
cardiogenic
circuitry
cldn23
cldn6
ece1
ednra
genic
hape
inciting
map2k2
map2k7
mapk10
mylk
oxphos
pak3
pathoetiology
plcb1
skew
sos1
unacclimatized
vasoconstriction
vcam1
Tagcloud (Difference)
?
acclimatized
adra1d
altitude
araf
argef11
arhgap24
ascent
cardiogenic
circuitry
cldn23
cldn6
ece1
ednra
genic
hape
inciting
map2k2
map2k7
mapk10
mylk
oxphos
pak3
pathoetiology
plcb1
skew
sos1
unacclimatized
vasoconstriction
vcam1
Tagcloud (Intersection)
?