PKD1 and SIAH1

  • Number of citations of the paper that reports this interaction (PMID 15284290)
  • 6
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)
  • HPRD (two hybrid, in vivo)

PKD1

SIAH1

Gene Name polycystic kidney disease 1 (autosomal dominant) siah E3 ubiquitin protein ligase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 25 interactors: ACTN1 ATF7IP BCAR1 CDH1 COL1A1 COL2A1 CTNNA1 CTNNB1 DES FN1 HDAC9 JAK2 JUP KRT18 KRT8 MARK2 PKD2 PTK2 PXN RGS7 SIAH1 SRC TLN1 VCL VIM 135 interactors: AASDHPPT AFF1 AFF4 APC AQP1 ARMC9 ATN1 ATXN7 BAG1 BCL6 C14orf105 CACYBP CAPG CDC23 CDC34 CDK5R1 CTNNB1 DAB1 DCC DDX41 DNAJC15 DNALI1 EEF1D EIF3J ELL2 EXOC3-AS1 FAM90A1 FLI1 FZD9 GAPDH GDPD5 GRM5 HIPK2 HIPK3 HIST4H4 INHA KATNAL1 KCNJ10 KHDRBS3 KIAA0319L KIAA1217 KIAA1683 KIF1B KIF22 KIFC3 LACTB2 MAB21L1 MAPK12 MAPKBP1 MAPRE3 MOB3C MTIF3 MX1 MYD88 NELFA NOL6 NUMB NUMBL OPRM1 OTUB2 PEG10 PEG3 PFKM PHC1 PHC2 PIAS1 PIAS2 PIAS3 PKD1 POU2AF1 PRPF31 PRR20A PTPMT1 PUF60 PVRL2 PYGB QRICH1 RAB33A RAD51AP1 RAD54L2 RAPH1 RBBP8 RPL27A RPS19BP1 SDCBP SH3RF1 SLC9A3R2 SNCA SNCAIP SPATA4 SPATC1L STAT3 SYP SYT7 TBC1D22B TERF2 TFDP1 TMEM43 TNK2 TOLLIP TP53BP2 TRIM23 TRIM27 TRIM7 TRIM8 TUBA1A TUBA1B TUBA3C TUBA4A TUBA8 TXN UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2I UBE2K UBE2L6 UBE2N UBE2V2 UPP2 USP19 UXT VAV1 WDYHV1 ZBP1 ZCCHC10 ZCCHC13 ZFYVE21 ZMAT3 ZNF148 ZNF512B ZNF671
Entrez ID 5310 6477
HPRD ID 03203 03736
Ensembl ID ENSG00000008710 ENSG00000196470
Uniprot IDs P98161 Q8IUQ4
PDB IDs 1B4R 2A25 4I7B 4I7C 4I7D
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acts  adpkd  autosomal  chaperone  coil  coiled  complexing  determinant  disrupted  distal  glycoform  gps  heterozygotes  illustrating  inherited  interbreeding  maturation  mature  missense  nephropathy  nonequimolar  pathogenic  pc1  pc2  pkd2  polycystic  polycystin  progressive  severity 
alleviates  anticancer  appears  cytotoxicity  debatable  decreases  degradation  demonstrating  downregulation  e3  exerts  increases  inducing  inhibiting  introduce  ligase  note  oncoprotein  p34sei  partly  polyubiquitination  prerequisite  previous  reveal  stronger  summary  ubiquitin  view  vitamin 
Tagcloud (Difference) ?
acts  adpkd  autosomal  chaperone  coil  coiled  complexing  determinant  disrupted  distal  glycoform  gps  heterozygotes  illustrating  inherited  interbreeding  maturation  mature  missense  nephropathy  nonequimolar  pathogenic  pc1  pc2  pkd2  polycystic  polycystin  progressive  severity 
alleviates  anticancer  appears  cytotoxicity  debatable  decreases  degradation  demonstrating  downregulation  e3  exerts  increases  inducing  inhibiting  introduce  ligase  note  oncoprotein  p34sei  partly  polyubiquitination  prerequisite  previous  reveal  stronger  summary  ubiquitin  view  vitamin 
Tagcloud (Intersection) ?