PXN and NF2

  • Number of citations of the paper that reports this interaction (PMID 12118253)
  • 21

PXN

NF2

Gene Name paxillin neurofibromin 2 (merlin)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Carotid atherosclerosis in HIV infection ( 20009918)
Protein-Protein Interactions 73 interactors: ABL1 AHCY AR ARHGEF7 ASAP1 ASAP2 BCAR1 BCL2 CASP3 CEACAM1 CLTC CREB3L2 CRK CRKL CSK DGUOK EPHB1 FYN GART GIT1 GIT2 GRB2 GSK3A GSK3B GSN HDAC6 ILK ITGA4 ITGA6 ITGA9 ITGB1 ITGB3 LCK LIMK1 MAPK1 MAPK3 MAPK8 MATK NCK1 NEDD9 NF2 PABPC1 PAK1 PAK3 PARVA PDPK1 PKD1 POLR1D PPP2CA PPP2R5C PTEN PTK2 PTK2B PTPN11 PTPN12 PTPRH RASA1 REPS2 RNF5 SDC4 SELE SORBS1 SRC SYK TLN1 TRIP6 TUBA1B TUBA3C TUBA8 TUBG1 TUBG2 VCL XPO1 24 interactors: AGAP2 AKT1 CCNB1IP1 CD44 CTNNB1 ERBB2 EZR HGS ITGB1 KDM1A MED28 PAK1 PXN PYGO2 RALGDS SCHIP1 SDCBP SGSM3 SLC9A3R1 SPTBN1 TARBP2 TSC1 VPRBP XPO1
Entrez ID 5829 4771
HPRD ID 03937 06980
Ensembl ID ENSG00000089159 ENSG00000186575
Uniprot IDs E7EMK8 F5GZ78 P49023 P35240
PDB IDs 1KKY 1KL0 1OW6 1OW7 1OW8 2K2R 2O9V 2VZD 2VZG 2VZI 3GM1 3PY7 3RQE 3RQF 3RQG 3U3C 3U3F 4EDN 1H4R 3U8Z
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acclimatized  adra1d  altitude  araf  argef11  arhgap24  ascent  cardiogenic  circuitry  cldn23  cldn6  ece1  ednra  genic  hape  inciting  map2k2  map2k7  mapk10  mylk  oxphos  pak3  pathoetiology  plcb1  skew  sos1  unacclimatized  vasoconstriction  vcam1 
22q  allele  alleles  analysed  assumed  candidates  carcinomas  colorectal  coupled  cys  digestive  e1a  gastric  gene  heterozygosity  inactivation  located  missense  mutation  neurofibromatosis  p300  participates  rich  sequencing  somatic  sscp  suppressor  though  thought 
Tagcloud (Difference) ?
acclimatized  adra1d  altitude  araf  argef11  arhgap24  ascent  cardiogenic  circuitry  cldn23  cldn6  ece1  ednra  genic  hape  inciting  map2k2  map2k7  mapk10  mylk  oxphos  pak3  pathoetiology  plcb1  skew  sos1  unacclimatized  vasoconstriction  vcam1 
22q  allele  alleles  analysed  assumed  candidates  carcinomas  colorectal  coupled  cys  digestive  e1a  gastric  gene  heterozygosity  inactivation  located  missense  mutation  neurofibromatosis  p300  participates  rich  sequencing  somatic  sscp  suppressor  though  thought 
Tagcloud (Intersection) ?