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PXN and TUBA1B
Number of citations of the paper that reports this interaction (PubMedID
10840040
)
0
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
PXN
TUBA1B
Description
paxillin
tubulin alpha 1b
Image
GO Annotations
Cellular Component
Stress Fiber
Cytoplasm
Cytosol
Cytoskeleton
Microtubule Associated Complex
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Cell Cortex
Lamellipodium
Anchoring Junction
Cytoplasm
Cytoskeleton
Microtubule
Cytoplasmic Microtubule
Cilium
Microtubule Cytoskeleton
Molecular Function
Protein Binding
Beta-catenin Binding
Vinculin Binding
Protein Phosphatase Binding
Neuropilin Binding
Metal Ion Binding
Nucleotide Binding
Double-stranded RNA Binding
GTPase Activity
Structural Molecule Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Hydrolase Activity
Ubiquitin Protein Ligase Binding
Biological Process
Cell Adhesion
Signal Transduction
Signal Complex Assembly
Transforming Growth Factor Beta Receptor Signaling Pathway
Cell Migration
Substrate Adhesion-dependent Cell Spreading
Cellular Response To Reactive Oxygen Species
Endothelial Cell Migration
Positive Regulation Of Stress Fiber Assembly
Growth Hormone Receptor Signaling Pathway
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Microtubule-based Process
Cytoskeleton-dependent Intracellular Transport
Cell Division
Cellular Response To Interleukin-4
Pathways
GAB1 signalosome
VEGFA-VEGFR2 Pathway
Smooth Muscle Contraction
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Recruitment of NuMA to mitotic centrosomes
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Recycling pathway of L1
Hedgehog 'off' state
Cargo trafficking to the periciliary membrane
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
Carboxyterminal post-translational modifications of tubulin
Carboxyterminal post-translational modifications of tubulin
RHOH GTPase cycle
HCMV Early Events
Assembly and cell surface presentation of NMDA receptors
Activation of AMPK downstream of NMDARs
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
PKR-mediated signaling
Drugs
Epothilone D
Patupilone
CYT997
2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases
GWAS
Bipolar disorder (
31043756
)
Left ventricle wall thickness (
33495596
)
Left ventricular end-systolic volume (
33495596
)
Left ventricular mass to end-diastolic volume ratio (
33495596
)
Mean spheric corpuscular volume (
32888494
)
Platelet count (
29403010
)
Ambidextrousness (
32989287
)
Bipolar disorder (
31043756
)
Brain morphology (MOSTest) (
32665545
)
Left-handedness (
32989287
)
Left–right brain asymmetry (
33723403
)
Interacting Genes
86 interacting genes:
ABL1
ACO1
AHCY
AR
ARHGEF7
ASAP1
ASAP2
BCAR1
BCL2
BLK
CASP3
CEACAM1
CLTC
CREB3L2
CRK
CRKL
CSK
DGUOK
DPY30
EPHB1
FYN
GART
GIT1
GIT2
GRB2
GSK3A
GSK3B
GSN
HDAC6
ILK
ITGA4
ITGA6
ITGA9
ITGAV
ITGB1
ITGB3
LCK
LIMK1
LINC00632
LMO1
LMO3
MAPK1
MAPK3
MAPK8
MATK
NCK1
NEDD9
NF2
PABPC1
PAK1
PAK3
PARVA
PDPK1
PKD1
PLEKHH2
POLR1D
PPP2CA
PPP2R5C
PTEN
PTK2
PTK2B
PTPN11
PTPN12
PTPRH
RASA1
REPS2
RHOU
RNF5
SDC4
SELE
SH3RF1
SORBS1
SRC
SYK
TCEANC
TGM2
TLN1
TRIM15
TRIP6
TUBA1B
TUBA3C
TUBA8
TUBG1
TUBG2
VCL
WHRN
39 interacting genes:
A2M
AGTRAP
EML4
EPN2
ESR1
FOXP1
FYN
GRM7
GZMM
HDAC6
ISG15
LINC00624
MAPT
MINK1
MTCL1
MYC
NFKBIA
OGT
PFDN5
PIK3R1
PSEN1
PTEN
PTP4A1
PTPRF
PXN
RNF26
RSPH1
RUNX1
SIAH1
SLX1B
SMAD2
SNAP91
SRPK2
SUMO2
TERT
TMEM253
TOM1L1
TUBG1
WEE2-AS1
Entrez ID
5829
10376
HPRD ID
03937
03960
Ensembl ID
ENSG00000089159
ENSG00000123416
Uniprot IDs
A0A140VJQ8
A0A1B0GTU4
F5GZ78
P49023
P68363
PDB IDs
1OW6
1OW7
1OW8
2K2R
2O9V
2VZD
2VZG
2VZI
3GM1
3PY7
3RQE
3RQF
3RQG
3U3F
4EDN
4R32
4XGZ
4XH2
5UWH
6IUI
6PW8
6U4M
6U4N
7QB0
2E4H
5IJ0
5IJ9
5N5N
6E7B
6E7C
6I2I
6J4V
6J8O
6QUS
6QUY
6QVE
6QVJ
6S8L
7LXB
7M18
7M20
7PJF
7SJ7
7SJ8
7SJ9
7SJA
7Z6S
7ZCW
8T42
8U3Z
8V2J
8VA2
8VRJ
8VRK
8VT7
9BP6
Enriched GO Terms of Interacting Partners
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Focal Adhesion
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of Cell Adhesion
Integrin-mediated Signaling Pathway
Cell Migration
Regulation Of Cellular Component Organization
Cell Surface Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Anchoring Junction
Cell Motility
Regulation Of Cytoskeleton Organization
Regulation Of Cell-substrate Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Cell Migration
Regulation Of Intracellular Signal Transduction
Cytosol
Regulation Of Cell Motility
Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Cell Migration
Regulation Of Locomotion
Positive Regulation Of Cell Motility
Positive Regulation Of Locomotion
Immune Response-regulating Cell Surface Receptor Signaling Pathway
ERBB Signaling Pathway
Signal Transduction
Immune Response-activating Cell Surface Receptor Signaling Pathway
Non-membrane Spanning Protein Tyrosine Kinase Activity
Phosphotyrosine Residue Binding
Cell-substrate Adhesion
Protein Kinase Activity
Regulation Of Cell-matrix Adhesion
Cell Projection Organization
Regulation Of Immune System Process
Lamellipodium
Plasma Membrane Bounded Cell Projection Organization
Positive Regulation Of Cellular Component Organization
Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Cytoplasm
Regulation Of MAPK Cascade
Plasma Membrane
Regulation Of Cellular Localization
Regulation Of Protein Localization
Immune Response-activating Signaling Pathway
Immune Response-regulating Signaling Pathway
Regulation Of Organelle Organization
Kinase Activity
Positive Regulation Of Immune System Process
Fc-gamma Receptor Signaling Pathway
Negative Regulation Of Developmental Process
Beta-catenin Binding
Neuron Projection Organization
Negative Regulation Of Cellular Component Organization
Regulation Of Myeloid Cell Differentiation
Regulation Of Cellular Component Organization
Regulation Of Multicellular Organismal Development
Negative Regulation Of Multicellular Organismal Process
Regulation Of Developmental Process
Regulation Of Signal Transduction
Regulation Of Cell Development
Regulation Of Cell Communication
Regulation Of Signaling
Response To Stress
Regulation Of Anatomical Structure Morphogenesis
Negative Regulation Of Cell Differentiation
Regulation Of Protein Localization To Nucleus
Enzyme Binding
Negative Regulation Of Cell Development
Positive Regulation Of Protein Oligomerization
Negative Regulation Of Signal Transduction
Negative Regulation Of Protein Metabolic Process
Growth Factor Receptor Binding
Dendritic Spine Organization
Ubiquitin Protein Ligase Binding
Negative Regulation Of Myeloid Cell Differentiation
Organelle Organization
Clathrin Binding
Negative Regulation Of Hydrogen Peroxide Metabolic Process
Positive Regulation Of Protein Localization To Nucleus
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Neuron Projection Development
Positive Regulation Of Signaling
Regulation Of Multicellular Organismal Process
Neuron Projection
Regulation Of Cell Differentiation
Cellular Response To Reactive Oxygen Species
Cellular Response To Stress
Alpha-tubulin Binding
Tau Protein Binding
Postsynapse Organization
Positive Regulation Of Signal Transduction
Positive Regulation Of Cellular Component Organization
Regulation Of Protein Localization
Negative Regulation Of Gene Expression
Protein Modification Process
Regulation Of Establishment Of Protein Localization
Inclusion Body Assembly
Regulation Of Myeloid Leukocyte Differentiation
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Tagcloud (Difference)
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Tagcloud (Intersection)
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