PXN and PTPN12

  • Number of citations of the paper that reports this interaction (PMID 10085298)
  • 61
  • Data Source:
  • HPRD (in vitro, in vivo, two hybrid)

PXN

PTPN12

Gene Name paxillin protein tyrosine phosphatase, non-receptor type 12
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 73 interactors: ABL1 AHCY AR ARHGEF7 ASAP1 ASAP2 BCAR1 BCL2 CASP3 CEACAM1 CLTC CREB3L2 CRK CRKL CSK DGUOK EPHB1 FYN GART GIT1 GIT2 GRB2 GSK3A GSK3B GSN HDAC6 ILK ITGA4 ITGA6 ITGA9 ITGB1 ITGB3 LCK LIMK1 MAPK1 MAPK3 MAPK8 MATK NCK1 NEDD9 NF2 PABPC1 PAK1 PAK3 PARVA PDPK1 PKD1 POLR1D PPP2CA PPP2R5C PTEN PTK2 PTK2B PTPN11 PTPN12 PTPRH RASA1 REPS2 RNF5 SDC4 SELE SORBS1 SRC SYK TLN1 TRIP6 TUBA1B TUBA3C TUBA8 TUBG1 TUBG2 VCL XPO1 37 interactors: ABL1 APP BAG6 BCAR1 CGA CSH1 CSH2 CSK EFS EGFR FLT3 GRB2 IFT20 INSR JAK2 LPXN MYCBP2 NEDD9 PRKACA PRKCA PSG9 PSTPIP1 PSTPIP2 PTK2 PTK2B PXN RBM19 SHC1 SMAD5 SORBS2 STX16 TEX10 TGFB1I1 THAP2 UTRN WAS ZFP2
Entrez ID 5829 5782
HPRD ID 03937 02513
Ensembl ID ENSG00000089159 ENSG00000127947
Uniprot IDs E7EMK8 F5GZ78 P49023 A4D1C5 B4E105 E9PBR5 Q05209
PDB IDs 1KKY 1KL0 1OW6 1OW7 1OW8 2K2R 2O9V 2VZD 2VZG 2VZI 3GM1 3PY7 3RQE 3RQF 3RQG 3U3C 3U3F 4EDN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acclimatized  adra1d  altitude  araf  argef11  arhgap24  ascent  cardiogenic  circuitry  cldn23  cldn6  ece1  ednra  genic  hape  inciting  map2k2  map2k7  mapk10  mylk  oxphos  pak3  pathoetiology  plcb1  skew  sos1  unacclimatized  vasoconstriction  vcam1 
cytoskeleton  dataset  deposited  dysregulation  exerts  expand  heterodimeric  http  identifier  inositol  inpp5d  mapkapk2  nad  nadk  nonreceptor  org  pertaining  phosphatases  phosphoproteome  phosphoproteomic  polyphosphate  proteomecentral  proteomexchange  pxd000984  reorganization  ripk1  silac  threonine  tnfrsf 
Tagcloud (Difference) ?
acclimatized  adra1d  altitude  araf  argef11  arhgap24  ascent  cardiogenic  circuitry  cldn23  cldn6  ece1  ednra  genic  hape  inciting  map2k2  map2k7  mapk10  mylk  oxphos  pak3  pathoetiology  plcb1  skew  sos1  unacclimatized  vasoconstriction  vcam1 
cytoskeleton  dataset  deposited  dysregulation  exerts  expand  heterodimeric  http  identifier  inositol  inpp5d  mapkapk2  nad  nadk  nonreceptor  org  pertaining  phosphatases  phosphoproteome  phosphoproteomic  polyphosphate  proteomecentral  proteomexchange  pxd000984  reorganization  ripk1  silac  threonine  tnfrsf 
Tagcloud (Intersection) ?