PTBP2 and MATR3

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		PTBP2	MATR3
Gene Name		polypyrimidine tract binding protein 2	matrin 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex	Nuclear Inner Membrane Nucleoplasm Membrane Nuclear Matrix
	Molecular Function	Nucleotide Binding MRNA Binding Poly(A) RNA Binding	Nucleotide Binding Structural Molecule Activity Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	MRNA Splice Site Selection Negative Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 20935630) Schizophrenia ( 19571811 22688191)
Protein-Protein Interactions		17 interactors: CALCOCO2 EIF5A2 ELAVL1 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PUF60 QKI RBM10 RBM4 SNRPA TOM1	13 interactors: AIMP2 CALM1 DISC1 EGFR ERG GFI1B HNRNPK PCBP1 PTBP2 RASD1 SNAP23 TNFRSF21 TTF2
Entrez ID		58155	9782
HPRD ID		12233	05270
Ensembl ID		ENSG00000117569	ENSG00000015479
Uniprot IDs		Q9UKA9	B3KM87 B4DF66 P43243 Q9H4N1
PDB IDs		2CQ1
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Posttranscriptional Regulation Of Gene Expression Regulation Of Translation Regulation Of MRNA Stability Regulation Of RNA Stability Gene Expression Positive Regulation Of Translation RNA Metabolic Process Circadian Regulation Of Translation RNA Splicing, Via Transesterification Reactions 3'-UTR-mediated MRNA Stabilization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process MRNA Transport RNA Transport RNA Localization Nitrogen Compound Metabolic Process MRNA Stabilization Positive Regulation Of Gene Expression MRNA Splicing, Via Spliceosome Polyamine Homeostasis Regulation Of Translational Initiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of RNA Export From Nucleus 3'-UTR-mediated MRNA Destabilization Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process IRES-dependent Translational Initiation Cap-independent Translational Initiation Translational Frameshifting Positive Regulation Of Translational Termination Positive Regulation Of Translational Elongation Spermatogenesis Male Gamete Generation MRNA Destabilization Positive Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Translation In Response To Stress Circadian Rhythm Macromolecule Biosynthetic Process Negative Regulation Of Translation Involved In Gene Silencing By MiRNA	RNA Splicing Second-messenger-mediated Signaling MRNA Processing Gene Expression MRNA Metabolic Process Regulation Of Nitric-oxide Synthase Activity RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Protein Metabolic Process Activation Of Phospholipase C Activity Cellular Response To Drug Negative Regulation Of Transmembrane Transport Positive Regulation Of Phospholipase C Activity Cell Proliferation Positive Regulation Of Transport Immune System Process Regulation Of Protein Metabolic Process Alkanesulfonate Metabolic Process Negative Regulation Of Potassium Ion Export RNA Metabolic Process Regulation Of Cell Proliferation Regulation Of Oxidoreductase Activity Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Phospholipase Activity Positive Regulation Of Ion Transmembrane Transport Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction Positive Regulation Of Lipase Activity Cerebral Cortex Cell Migration Positive Regulation Of Protein Modification Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Pharynx Development Regulation Of Heart Rate By Hormone Negative Regulation Of Interleukin-13 Secretion Negative Regulation Of Interleukin-5 Secretion Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Oligodendrocyte Apoptotic Process Astrocyte Activation Negative Regulation Of Transport Calcium-mediated Signaling Multicellular Organismal Development Hair Follicle Development Hair Cycle Process Negative Regulation Of Ion Transport
Tagcloud ?		17beta abolishment adenocarcinoma asos colony downregulated downregulation dramatically e2 ectopic emt eralpha estradiol estrogen evaluating invasion malat mesenchymal migration mir necessity os osteoblast osteosarcoma posttranscriptionally remarkably sfpq transcript ways	3o 5o ahdc1 arteriosus bav bicuspid breakpoint coarctation disturb dorv ductus ex13 genet heterozygotes hook hum lvot matrin outlet pda penetrant pervasive polyadenylation proband probandos q31 truncating vsd
Tagcloud (Difference) ?		17beta abolishment adenocarcinoma asos colony downregulated downregulation dramatically e2 ectopic emt eralpha estradiol estrogen evaluating invasion malat mesenchymal migration mir necessity os osteoblast osteosarcoma posttranscriptionally remarkably sfpq transcript ways	3o 5o ahdc1 arteriosus bav bicuspid breakpoint coarctation disturb dorv ductus ex13 genet heterozygotes hook hum lvot matrin outlet pda penetrant pervasive polyadenylation proband probandos q31 truncating vsd
Tagcloud (Intersection) ?