PTBP2 and KHDRBS3

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		PTBP2	KHDRBS3
Gene Name		polypyrimidine tract binding protein 2	KH domain containing, RNA binding, signal transduction associated 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex	Nucleus Nucleoplasm
	Molecular Function	Nucleotide Binding MRNA Binding Poly(A) RNA Binding	RNA Binding Protein Binding SH3 Domain Binding Poly(A) RNA Binding
	Biological Process	MRNA Splice Site Selection Negative Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Spermatogenesis
Pathways
Drugs
Diseases
GWAS		Body mass index ( 20935630) Schizophrenia ( 19571811 22688191)
Protein-Protein Interactions		17 interactors: CALCOCO2 EIF5A2 ELAVL1 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PUF60 QKI RBM10 RBM4 SNRPA TOM1	30 interactors: BAHD1 CACNA1A CCDC33 DMRT3 FUS HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LNX1 MARK4 NCOA5 NELFB NUDT18 PRMT1 PRPF31 PSMF1 PTBP2 RBBP6 RBM7 RBMX RBMY1A1 SGSM2 SIAH1 SNRPC SRSF9 U2AF2 YTHDC1 ZNF408
Entrez ID		58155	10656
HPRD ID		12233	10007
Ensembl ID		ENSG00000117569	ENSG00000131773
Uniprot IDs		Q9UKA9	O75525
PDB IDs		2CQ1
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Posttranscriptional Regulation Of Gene Expression Regulation Of Translation Regulation Of MRNA Stability Regulation Of RNA Stability Gene Expression Positive Regulation Of Translation RNA Metabolic Process Circadian Regulation Of Translation RNA Splicing, Via Transesterification Reactions 3'-UTR-mediated MRNA Stabilization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process MRNA Transport RNA Transport RNA Localization Nitrogen Compound Metabolic Process MRNA Stabilization Positive Regulation Of Gene Expression MRNA Splicing, Via Spliceosome Polyamine Homeostasis Regulation Of Translational Initiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of RNA Export From Nucleus 3'-UTR-mediated MRNA Destabilization Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process IRES-dependent Translational Initiation Cap-independent Translational Initiation Translational Frameshifting Positive Regulation Of Translational Termination Positive Regulation Of Translational Elongation Spermatogenesis Male Gamete Generation MRNA Destabilization Positive Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Translation In Response To Stress Circadian Rhythm Macromolecule Biosynthetic Process Negative Regulation Of Translation Involved In Gene Silencing By MiRNA	MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Metabolic Process RNA Processing Gene Expression RNA Metabolic Process Negative Regulation Of RNA Splicing Cellular Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing MRNA Splice Site Selection Spliceosomal Complex Assembly Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Assembly Regulation Of MRNA Processing Metabolic Process Regulation Of Metabolic Process Ribonucleoprotein Complex Biogenesis Regulation Of Gene Expression Transcription, DNA-templated Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Cellular Component Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Gene Expression Cellular Macromolecular Complex Assembly Positive Regulation Of RNA Splicing Spliceosomal SnRNP Assembly Termination Of RNA Polymerase II Transcription Cerebellar Molecular Layer Development DGDP Catabolic Process DADP Catabolic Process GDP Catabolic Process Adult Walking Behavior Cellular Process Cellular Macromolecule Biosynthetic Process Ventral Spinal Cord Development Transmission Of Nerve Impulse Macromolecule Biosynthetic Process Vestibular Nucleus Development
Tagcloud ?		17beta abolishment adenocarcinoma asos colony downregulated downregulation dramatically e2 ectopic emt eralpha estradiol estrogen evaluating invasion malat mesenchymal migration mir necessity os osteoblast osteosarcoma posttranscriptionally remarkably sfpq transcript ways
Tagcloud (Difference) ?		17beta abolishment adenocarcinoma asos colony downregulated downregulation dramatically e2 ectopic emt eralpha estradiol estrogen evaluating invasion malat mesenchymal migration mir necessity os osteoblast osteosarcoma posttranscriptionally remarkably sfpq transcript ways
Tagcloud (Intersection) ?