PTBP2 and PCBP3

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PTBP2	PCBP3
Gene Name		polypyrimidine tract binding protein 2	poly(rC) binding protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex	Nucleus Cytosol Ribonucleoprotein Complex Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding MRNA Binding Poly(A) RNA Binding	DNA Binding RNA Binding Poly(A) RNA Binding
	Biological Process	MRNA Splice Site Selection Negative Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation	MRNA Metabolic Process
Pathways
Drugs
Diseases
GWAS		Body mass index ( 20935630) Schizophrenia ( 19571811 22688191)	Insulin resistance/response ( 21901158)
Protein-Protein Interactions		17 interactors: CALCOCO2 EIF5A2 ELAVL1 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PUF60 QKI RBM10 RBM4 SNRPA TOM1	2 interactors: PTBP1 PTBP2
Entrez ID		58155	54039
HPRD ID		12233	10534
Ensembl ID		ENSG00000117569	ENSG00000183570
Uniprot IDs		Q9UKA9	P57721
PDB IDs		2CQ1
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Posttranscriptional Regulation Of Gene Expression Regulation Of Translation Regulation Of MRNA Stability Regulation Of RNA Stability Gene Expression Positive Regulation Of Translation RNA Metabolic Process Circadian Regulation Of Translation RNA Splicing, Via Transesterification Reactions 3'-UTR-mediated MRNA Stabilization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process MRNA Transport RNA Transport RNA Localization Nitrogen Compound Metabolic Process MRNA Stabilization Positive Regulation Of Gene Expression MRNA Splicing, Via Spliceosome Polyamine Homeostasis Regulation Of Translational Initiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of RNA Export From Nucleus 3'-UTR-mediated MRNA Destabilization Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process IRES-dependent Translational Initiation Cap-independent Translational Initiation Translational Frameshifting Positive Regulation Of Translational Termination Positive Regulation Of Translational Elongation Spermatogenesis Male Gamete Generation MRNA Destabilization Positive Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Translation In Response To Stress Circadian Rhythm Macromolecule Biosynthetic Process Negative Regulation Of Translation Involved In Gene Silencing By MiRNA	Negative Regulation Of RNA Splicing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Gene Expression MRNA Splice Site Selection Negative Regulation Of Muscle Cell Differentiation Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Negative Regulation Of Cellular Metabolic Process Regulation Of Neural Precursor Cell Proliferation Regulation Of Muscle Cell Differentiation Ribonucleoprotein Complex Assembly RNA Metabolic Process Gene Expression
Tagcloud ?		17beta abolishment adenocarcinoma asos colony downregulated downregulation dramatically e2 ectopic emt eralpha estradiol estrogen evaluating invasion malat mesenchymal migration mir necessity os osteoblast osteosarcoma posttranscriptionally remarkably sfpq transcript ways
Tagcloud (Difference) ?		17beta abolishment adenocarcinoma asos colony downregulated downregulation dramatically e2 ectopic emt eralpha estradiol estrogen evaluating invasion malat mesenchymal migration mir necessity os osteoblast osteosarcoma posttranscriptionally remarkably sfpq transcript ways
Tagcloud (Intersection) ?