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PTPRN and PTPRS
Number of citations of the paper that reports this interaction (PubMedID
16273344
)
0
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro, two hybrid)
PTPRN
PTPRS
Description
protein tyrosine phosphatase receptor type N
protein tyrosine phosphatase receptor type S
Image
GO Annotations
Cellular Component
Nucleus
Endosome
Golgi Apparatus
Plasma Membrane
Synaptic Vesicle
Membrane
Secretory Granule
Axon
Transport Vesicle Membrane
Cytoplasmic Vesicle
Cell Projection
Neuronal Cell Body
Perikaryon
Axon Terminus
Synapse
Cytosol
Plasma Membrane
Postsynaptic Density
Membrane
Axon
Growth Cone
Synaptic Vesicle Membrane
Cytoplasmic Vesicle
Presynaptic Membrane
Cell Projection
Neuron Projection
Perikaryon
Synapse
Extracellular Exosome
Schaffer Collateral - CA1 Synapse
Postsynaptic Density Membrane
Glutamatergic Synapse
Molecular Function
Protein Tyrosine Phosphatase Activity
Protein Binding
Transcription Factor Binding
Spectrin Binding
Ubiquitin-like Protein Ligase Binding
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Heparin Binding
Hydrolase Activity
Chondroitin Sulfate Binding
Heparan Sulfate Proteoglycan Binding
Biological Process
Response To Reactive Oxygen Species
Luteinization
Insulin Secretion
Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Secretion
Positive Regulation Of Type B Pancreatic Cell Proliferation
Dense Core Granule Maturation
Protein Dephosphorylation
Cell Adhesion
Signal Transduction
Negative Regulation Of Neuron Projection Development
Spinal Cord Development
Cerebellum Development
Hippocampus Development
Cerebral Cortex Development
Corpus Callosum Development
Negative Regulation Of Axon Extension
Negative Regulation Of Interferon-alpha Production
Negative Regulation Of Interferon-beta Production
Negative Regulation Of Toll-like Receptor 9 Signaling Pathway
Peptidyl-tyrosine Dephosphorylation
Negative Regulation Of Collateral Sprouting
Negative Regulation Of Axon Regeneration
Modulation Of Chemical Synaptic Transmission
Synapse Organization
Negative Regulation Of Dendritic Spine Development
Establishment Of Endothelial Intestinal Barrier
Regulation Of Postsynaptic Density Assembly
Trans-synaptic Signaling
Synaptic Membrane Adhesion
Pathways
ECM proteoglycans
Receptor-type tyrosine-protein phosphatases
Synaptic adhesion-like molecules
Signaling by NTRK3 (TRKC)
Drugs
Alendronic acid
Etidronic acid
Diseases
GWAS
High light scatter reticulocyte count (
27863252
)
High light scatter reticulocyte percentage of red cells (
27863252
)
Mean reticulocyte volume (
32888494
)
Thyroid stimulating hormone levels (
32769997
)
Type 2 diabetes (
30297969
)
Waist-hip ratio (
28552196
)
Interacting Genes
19 interacting genes:
CAPN2
CCDC134
CLN8
GJA8
GPR152
MADD
MAL
NOS1
PLP1
PPIA
PTPRS
PTPRT
SNTB2
SNX19
SPTBN4
TIMMDC1
TMEM80
TRDN
UBQLN4
28 interacting genes:
CEP126
CHD3
EEF1G
EGFR
FEZ1
GPC2
GPC3
GPC6
KAT5
MOB4
OMG
PFN2
PPFIA1
PPFIA2
PPFIA3
PTN
PTPRA
PTPRD
PTPRE
PTPRM
PTPRN
RAB35
SETDB1
SLITRK1
TUBB2A
UBR1
UNC119
UTP14A
Entrez ID
5798
5802
HPRD ID
03466
03344
Ensembl ID
ENSG00000054356
ENSG00000105426
Uniprot IDs
Q16849
Q96IA0
Q13332
Q59FX6
Q8NHS7
PDB IDs
2I1Y
2QT7
3N01
3N4W
3NG8
3NP5
2FH7
2YD2
2YD3
2YD9
4BPC
4PBX
Enriched GO Terms of Interacting Partners
?
Membrane
Structural Constituent Of Myelin Sheath
Central Nervous System Myelination
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway
Protein Tyrosine Phosphatase Activity
Regulation Of Protein Localization To Membrane
Schaffer Collateral - CA1 Synapse
Regulation Of Cellular Component Organization
Cell Adhesion
Side Of Membrane
Synapse Organization
Presynaptic Active Zone
Regulation Of Neuron Projection Development
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Phosphoprotein Phosphatase Activity
Regulation Of Cell Projection Organization
Positive Regulation Of Neuron Projection Development
Regulation Of Cellular Localization
Glutamatergic Synapse
Positive Regulation Of Cell Projection Organization
Regulation Of Stem Cell Differentiation
Regulation Of Epithelial Cell Proliferation
Positive Regulation Of Cellular Component Organization
Lysosomal Lumen
Presynapse Organization
Intercellular Bridge
Positive Regulation Of Peptidyl-serine Phosphorylation
Golgi Lumen
Synapse
Synaptic Membrane Adhesion
Microtubule Cytoskeleton Organization
Cell Junction Organization
Neuron Projection Regeneration
Neuron Projection Development
Regulation Of Peptidyl-serine Phosphorylation
Modulation Of Chemical Synaptic Transmission
Cellular Response To Estradiol Stimulus
Multivesicular Body, Internal Vesicle Lumen
Peptidyl-dipeptidase Inhibitor Activity
Cell Projection Organization
Structural Constituent Of Presynapse
Epididymosome
Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion
Histone H2AK5 Acetyltransferase Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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