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PTPRN

Description protein tyrosine phosphatase receptor type N
Image
GO Annotations Cellular Component
  • Nucleus
  • Endosome
  • Golgi Apparatus
  • Plasma Membrane
  • Synaptic Vesicle
  • Membrane
  • Secretory Granule
  • Axon
  • Transport Vesicle Membrane
  • Cytoplasmic Vesicle
  • Cell Projection
  • Neuronal Cell Body
  • Perikaryon
  • Axon Terminus
  • Synapse
Molecular Function
  • Protein Tyrosine Phosphatase Activity
  • Protein Binding
  • Transcription Factor Binding
  • Spectrin Binding
  • Ubiquitin-like Protein Ligase Binding
Biological Process
  • Response To Reactive Oxygen Species
  • Luteinization
  • Insulin Secretion
  • Insulin Secretion Involved In Cellular Response To Glucose Stimulus
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Regulation Of Secretion
  • Positive Regulation Of Type B Pancreatic Cell Proliferation
  • Dense Core Granule Maturation
Pathways
Drugs
Diseases
GWAS
  • High light scatter reticulocyte count ( 27863252)
  • High light scatter reticulocyte percentage of red cells ( 27863252)
  • Mean reticulocyte volume ( 32888494)
Interacting Genes 19 interacting genes: CAPN2 CCDC134 CLN8 GJA8 GPR152 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 TIMMDC1 TMEM80 TRDN UBQLN4
Entrez ID 5798
HPRD ID 03466
Ensembl ID ENSG00000054356
Uniprot IDs Q16849 Q96IA0
PDB IDs 2I1Y 2QT7 3N01 3N4W 3NG8 3NP5
Enriched GO Terms of Interacting Partners?
  • Membrane
  • Structural Constituent Of Myelin Sheath
  • Central Nervous System Myelination
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