PTPRN and PLP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PTPRN	PLP1
Gene Name		protein tyrosine phosphatase, receptor type, N	proteolipid protein 1
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane Myelin Sheath
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Spectrin Binding GTPase Binding	Structural Molecule Activity Structural Constituent Of Myelin Sheath
	Biological Process	Response To Reactive Oxygen Species Protein Dephosphorylation Response To Glucose Cytokine-mediated Signaling Pathway Insulin Secretion Response To Insulin Response To Estrogen Response To CAMP Dense Core Granule Maturation	Inflammatory Response Integrin-mediated Signaling Pathway Synaptic Transmission Axon Ensheathment Positive Regulation Of Gene Expression Astrocyte Development Substantia Nigra Development Central Nervous System Myelination Long-chain Fatty Acid Biosynthetic Process Cell Maturation Axon Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CAPN2 CLN8 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 UBQLN4	7 interactors: CALR CANX CLN8 ITGAV MAG MBP PTPRN
Entrez ID		5798	5354
HPRD ID		03466	02321
Ensembl ID		ENSG00000054356	ENSG00000123560
Uniprot IDs		Q16849 Q96IA0	A8K9L3 B4DI30 P60201
PDB IDs		2I1Y 2QT7 3N01 3N4W 3NG8 3NP5	2XPG
Enriched GO Terms of Interacting Partners?		Myoblast Fusion Central Nervous System Development Syncytium Formation Regulation Of Cellular Protein Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Adult Walking Behavior Regulation Of Protein Metabolic Process Myotube Differentiation Cell Differentiation Muscle Cell Differentiation Regulation Of Sodium Ion Transport Positive Regulation Of Interleukin-15 Production Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Cytotoxic T Cell Differentiation TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Uncoating Of Virus Anatomical Structure Development Response To Stimulus Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Dense Core Granule Maturation L-glutamate Uptake Involved In Synaptic Transmission Interaction With Host Spinal Cord Development Adult Locomotory Behavior Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Serotonin Uptake Membrane Raft Polarization Viral Release From Host Cell Developmental Process Muscle Structure Development Signaling Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Positive Regulation Of The Force Of Heart Contraction Regulation Of Generation Of L-type Calcium Current Cell Communication Regulation Of Neurotransmitter Levels Cell Maturation Myelination Peptidyl-cysteine S-nitrosylation Membrane Raft Localization Axon Ensheathment Regulation Of Adrenergic Receptor Signaling Pathway Age-dependent Response To Oxidative Stress Regulation Of Heart Contraction Adult Behavior Peptidyl-tyrosine Dephosphorylation See more	Aging Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Negative Regulation Of Neuron Differentiation Generation Of Neurons Negative Regulation Of Cell Differentiation Antigen Processing And Presentation Of Peptide Antigen Neurogenesis Substantia Nigra Development Response To Stress Antigen Processing And Presentation Negative Regulation Of Neurogenesis Positive Regulation Of Phagocytosis Negative Regulation Of Cell Development Neural Nucleus Development Immune System Process Chaperone-mediated Protein Folding Negative Regulation Of Axonogenesis Nervous System Development Regulation Of Phagocytosis Regulation Of Cell Morphogenesis Response To Steroid Hormone Midbrain Development Peptide Antigen Assembly With MHC Class I Protein Complex Negative Regulation Of Entry Of Bacterium Into Host Cell Entry Of Symbiont Into Host Cell By Promotion Of Host Phagocytosis Negative Regulation Of Cell Morphogenesis Involved In Differentiation Protein N-linked Glycosylation Via Asparagine Regulation Of Neuron Differentiation Positive Regulation Of Endocytosis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Negative Regulation Of Neuron Projection Development Protein N-linked Glycosylation Protein Secretion Regulation Of Cell Differentiation Regulation Of Entry Of Bacterium Into Host Cell Dense Core Granule Maturation L-glutamate Uptake Involved In Synaptic Transmission Endocytosis Negative Regulation Of Cell Projection Organization Regulation Of Neurogenesis Defense Response To Nematode Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Developmental Process Regulation Of Axonogenesis Cell Differentiation Signaling Cell Communication Sequestering Of Calcium Ion Regulation Of Cellular Component Organization See more
Tagcloud ?		2j allen atlas b6 bc023892 btg3 bves drd5 edinger egr1 ew ewcp ewpg ghsr housekeeping microdissection neto1 neurogenetic neuropeptides oculomotor peptidergic postn preganglionic projecting publicly punch rcn1 ucn westphal	bace1 bingo cdk2 clustering criterion cytoscape degs downloaded elavl1 glioma gse31262 hierarchical kif23 kobas language limma log2fc mbp multtest myelination omnibus ontology package pheatmap plug software string webgestalt wee1
Tagcloud (Difference) ?		2j allen atlas b6 bc023892 btg3 bves drd5 edinger egr1 ew ewcp ewpg ghsr housekeeping microdissection neto1 neurogenetic neuropeptides oculomotor peptidergic postn preganglionic projecting publicly punch rcn1 ucn westphal	bace1 bingo cdk2 clustering criterion cytoscape degs downloaded elavl1 glioma gse31262 hierarchical kif23 kobas language limma log2fc mbp multtest myelination omnibus ontology package pheatmap plug software string webgestalt wee1
Tagcloud (Intersection) ?