PTPRN and SNTB2

Number of citations of the paper that reports this interaction (PubMedID 11483505)
72

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		PTPRN	SNTB2
Description		protein tyrosine phosphatase receptor type N	syntrophin beta 2
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GO Annotations	Cellular Component	Nucleus Endosome Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Secretory Granule Axon Transport Vesicle Membrane Cytoplasmic Vesicle Cell Projection Neuronal Cell Body Perikaryon Axon Terminus Synapse	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Microtubule Plasma Membrane Focal Adhesion Dystrophin-associated Glycoprotein Complex Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Protein-containing Complex Centriolar Satellite Ciliary Basal Body Synapse Anchoring Junction
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Transcription Factor Binding Spectrin Binding Ubiquitin-like Protein Ligase Binding	RNA Binding Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding
	Biological Process	Response To Reactive Oxygen Species Luteinization Insulin Secretion Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Secretion Positive Regulation Of Type B Pancreatic Cell Proliferation Dense Core Granule Maturation
Pathways			Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Mean reticulocyte volume ( 32888494)	Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		19 interacting genes: CAPN2 CCDC134 CLN8 GJA8 GPR152 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 TIMMDC1 TMEM80 TRDN UBQLN4	16 interacting genes: ABCA1 ADGRB1 ADRA1D DGKZ DMD DTNA ERBB4 KCNJ12 MAST1 MAST2 PTEN PTPRN SCN4A SCN5A UBC UTRN
Entrez ID		5798	6645
HPRD ID		03466	02491
Ensembl ID		ENSG00000054356	ENSG00000168807
Uniprot IDs		Q16849 Q96IA0	Q13425
PDB IDs		2I1Y 2QT7 3N01 3N4W 3NG8 3NP5	2VRF
Enriched GO Terms of Interacting Partners?		Membrane Structural Constituent Of Myelin Sheath Central Nervous System Myelination	Plasma Membrane Muscle Contraction Muscle System Process Sarcolemma Regulation Of System Process Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Membrane Cell Communication System Process Regulation Of Sodium Ion Transport PDZ Domain Binding Vinculin Binding Striated Muscle Contraction Nitric-oxide Synthase Binding Voltage-gated Sodium Channel Complex Regulation Of Multicellular Organismal Process Regulation Of Blood Circulation Dystrophin-associated Glycoprotein Complex Regulation Of Striated Muscle Contraction Voltage-gated Sodium Channel Activity Synapse Regulation Of Monoatomic Ion Transmembrane Transport Filopodium Membrane Action Potential Regulation Of Skeletal Muscle Contraction Regulation Of Biological Quality Cell-cell Signaling Muscle Organ Development Monoatomic Ion Channel Complex Signaling Synaptic Signaling Muscle Structure Development Regulation Of Transport Phagocytosis, Engulfment Phosphorylation Monoatomic Cation Channel Activity Regulation Of Monoatomic Ion Transport Sodium Channel Activity Regulation Of Muscle Contraction Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Membrane Potential Cell Projection Cardiac Muscle Contraction Membrane Invagination Sphingolipid Floppase Activity Regulation Of Heart Contraction Positive Regulation Of Epithelial Cell Proliferation Establishment Of Planar Polarity Involved In Nephron Morphogenesis T-tubule
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