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KMT2B
Gene Name
lysine (K)-specific methyltransferase 2B
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Histone Methyltransferase Complex
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Histone Methyltransferase Activity (H3-K4 Specific)
Biological Process
Ovarian Follicle Development
Chromatin Organization
Transcription, DNA-templated
Oocyte Differentiation
Gene Silencing
Ovulation
Chromatin-mediated Maintenance Of Transcription
Histone H3-K4 Methylation
Regulation Of Histone H3-K4 Methylation
Histone H3-K4 Trimethylation
Pathways
Chromatin modifying enzymes
Chromatin organization
PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Protein-protein Interactions
22 interactors:
ANXA1
ANXA7
ATP1B1
ATXN1
CDKN1A
GRB7
HIST1H3A
HIST2H3C
NREP
PIN1
PRPF40A
RAP1B
RCC1
RPP14
SEPT8
SMAD3
SMARCB1
SMN1
TK1
TSC22D1
WDR5
ZNF512B
Entrez ID
9757
HPRD ID
06017
Ensembl ID
ENSG00000272333
Uniprot IDs
Q9UMN6
PDB IDs
3UVM
4ERZ
Enriched GO Terms of Interacting Partners
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Hemostasis
Response To Wounding
Regulation Of Body Fluid Levels
Response To Stress
Wound Healing
Regulation Of Mitotic Cell Cycle
Blood Coagulation
Nucleobase-containing Compound Metabolic Process
DNA Methylation On Cytosine
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cell Cycle Process
Regulation Of Metabolic Process
Chromatin Silencing At RDNA
Cellular Nitrogen Compound Metabolic Process
Epithelial Cell Differentiation
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Response To Organic Cyclic Compound
Gene Silencing
Negative Regulation Of Gene Expression
Cell Cycle
Regulation Of Cell Cycle
Regulation Of Cellular Component Organization
Digestive Tract Development
Nitrogen Compound Metabolic Process
Digestive System Development
Response To Abiotic Stimulus
Liver Development
Response To X-ray
Response To Glucocorticoid
Positive Regulation Of Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Phosphorylation
Gene Expression
Response To Corticosteroid
Chromatin Silencing
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Gene Expression, Epigenetic
Neutrophil Clearance
Positive Regulation Of Transforming Growth Factor Beta3 Production
Fetal Process Involved In Parturition
Regulation Of Cell Junction Assembly
RNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cytokinesis
DNA Methylation
Cellular Process
Regulation Of Cell Division
RNA Processing
Mitotic Cell Cycle Phase Transition
Tagcloud
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alters
associates
demethylase
h3k4
h3k4me3
hmt
hyperplastic
igf2bp2
integrative
interactive
islet
islets
jarid1
jumonji
kdm5a
kmt2a
landscape
men1
menin
methyltransferases
mll1
mll4
neuroendocrine
pancreatic
pannets
rbp2
seq
trimethylation
unbiased