UXT and TRIM55

Number of citations of the paper that reports this interaction (PMID 18157088)
41

Data Source:
BioGRID (two hybrid)

		UXT	TRIM55
Gene Name		ubiquitously-expressed, prefoldin-like chaperone	tripartite motif containing 55
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Cytoskeleton	Nucleus Cytoplasm Microtubule
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	Signal Transducer Activity Zinc Ion Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Microtubule Cytoskeleton Organization Transcription, DNA-templated Mitochondrion Transport Along Microtubule Centrosome Organization	Signal Transduction
Pathways
Drugs
Diseases
GWAS			Response to statin therapy ( 22666496)
Protein-Protein Interactions		19 interactors: APP AR CECR2 GLE1 KRT31 KRT40 KRTAP10-7 KRTAP10-8 LRPPRC LSM1 NOTCH2NL PAK7 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL	61 interactors: ACTA1 ANKRD1 ATP5B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1
Entrez ID		8409	84675
HPRD ID		02209	05927
Ensembl ID		ENSG00000126756	ENSG00000147573
Uniprot IDs		Q9UBK9	Q9BYV6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Growth Single-organism Behavior Posttranscriptional Regulation Of Gene Expression Locomotory Behavior Behavior Neuron Apoptotic Process Learning Or Memory Negative Regulation Of Integrin Biosynthetic Process Developmental Process Neuron Death Cognition Synaptic Growth At Neuromuscular Junction Positive Regulation Of Progesterone Secretion Negative Regulation Of Mitochondrial RNA Catabolic Process Anatomical Structure Development Collateral Sprouting In Absence Of Injury Positive Regulation Of Integrin Biosynthetic Process Regulation Of Progesterone Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Hair Follicle Cell Proliferation Regulation Of Integrin Biosynthetic Process MRNA Transport Neuron Development Memory Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Steroid Hormone Microtubule-based Transport Programmed Cell Death Regulation Of Protein Stability Skeletal Muscle Tissue Development RNA Transport Learning Notch Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Skeletal Muscle Atrophy Growth Cytoskeleton-dependent Intracellular Transport Tissue Development Cell Death Death Skeletal Muscle Organ Development RNA Localization Axon Choice Point Recognition Striated Muscle Atrophy Response To Abiotic Stimulus	Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Protein Deubiquitination Protein Modification By Small Protein Removal Actin Filament-based Movement Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Muscle Contraction Actin Filament-based Process Cellular Protein Catabolic Process Protein Catabolic Process Muscle System Process Protein K48-linked Deubiquitination Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Striated Muscle Cell Development Cellular Protein Metabolic Process Muscle Structure Development Muscle Cell Development Protein K63-linked Deubiquitination Myofibril Assembly Proteolysis Cellular Protein Modification Process Striated Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Striated Muscle Cell Differentiation Muscle Tissue Development Muscle Tissue Morphogenesis Actomyosin Structure Organization Muscle Organ Morphogenesis Cardiac Muscle Tissue Development Protein Metabolic Process Muscle Organ Development Protein Modification By Small Protein Conjugation Muscle Cell Differentiation Myosin Filament Assembly Catabolic Process Actin Cytoskeleton Organization Skeletal Muscle Thin Filament Assembly Cytoskeleton Organization Skeletal Myofibril Assembly Response To Muscle Stretch Heart Morphogenesis Striated Muscle Contraction Cellular Process
Tagcloud ?		angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel zebrafish
Tagcloud (Difference) ?		angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel zebrafish
Tagcloud (Intersection) ?