UXT and GLE1

Number of citations of the paper that reports this interaction (PMID 14645504)
18

Data Source:
BioGRID (two hybrid)

		UXT	GLE1
Gene Name		ubiquitously-expressed, prefoldin-like chaperone	GLE1 RNA export mediator
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Cytoskeleton	Extracellular Space Nuclear Pore Cytoplasm Plasma Membrane Membrane
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Microtubule Cytoskeleton Organization Transcription, DNA-templated Mitochondrion Transport Along Microtubule Centrosome Organization	MRNA Export From Nucleus Protein Transport Poly(A)+ MRNA Export From Nucleus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: APP AR CECR2 GLE1 KRT31 KRT40 KRTAP10-7 KRTAP10-8 LRPPRC LSM1 NOTCH2NL PAK7 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL	4 interactors: KRT10 NUP155 NUPL2 UXT
Entrez ID		8409	2733
HPRD ID		02209	04536
Ensembl ID		ENSG00000126756	ENSG00000119392
Uniprot IDs		Q9UBK9	B3KMG0 Q53GS7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Growth Single-organism Behavior Posttranscriptional Regulation Of Gene Expression Locomotory Behavior Behavior Neuron Apoptotic Process Learning Or Memory Negative Regulation Of Integrin Biosynthetic Process Developmental Process Neuron Death Cognition Synaptic Growth At Neuromuscular Junction Positive Regulation Of Progesterone Secretion Negative Regulation Of Mitochondrial RNA Catabolic Process Anatomical Structure Development Collateral Sprouting In Absence Of Injury Positive Regulation Of Integrin Biosynthetic Process Regulation Of Progesterone Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Hair Follicle Cell Proliferation Regulation Of Integrin Biosynthetic Process MRNA Transport Neuron Development Memory Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Steroid Hormone Microtubule-based Transport Programmed Cell Death Regulation Of Protein Stability Skeletal Muscle Tissue Development RNA Transport Learning Notch Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Skeletal Muscle Atrophy Growth Cytoskeleton-dependent Intracellular Transport Tissue Development Cell Death Death Skeletal Muscle Organ Development RNA Localization Axon Choice Point Recognition Striated Muscle Atrophy Response To Abiotic Stimulus	Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Transcription Regulation Of Glucose Transport Nuclear Export MRNA Transport Nucleus Organization Carbohydrate Transport RNA Transport RNA Localization Viral Life Cycle Pathogenesis Nucleocytoplasmic Transport Nuclear Transport Intracellular Transport Atrial Cardiac Muscle Cell To AV Node Cell Communication Atrial Cardiac Muscle Cell Action Potential Endomembrane System Organization Cytokine-mediated Signaling Pathway Establishment Of Localization In Cell Mitochondrion Transport Along Microtubule Cell-cell Signaling Involved In Cardiac Conduction Establishment Of Mitochondrion Localization Viral Process Cellular Response To Cytokine Stimulus RNA Biosynthetic Process Cellular Localization Cardiac Muscle Cell Action Potential Involved In Contraction Mitotic Cell Cycle Process Cytoplasmic Transport Response To Cytokine Mitotic Cell Cycle Mitochondrion Localization Cardiac Muscle Cell Action Potential Protein Export From Nucleus Membrane Organization Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Cellular Response To Calcium Ion Intracellular Protein Transport Organelle Organization RNA Metabolic Process Organelle Transport Along Microtubule Carbohydrate Metabolic Process Cell Cycle Process Gene Expression MRNA Export From Nucleus
Tagcloud ?		angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel zebrafish	als amyotrophic arthrogryposis autosomal carries causative congenital contracture deleterious export fatal fus global haploinsufficiency hela hgle1 horn lethal missense morphants motor neuron nonsense pore recessive rescue splice unable zebrafish
Tagcloud (Difference) ?		angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel	als amyotrophic arthrogryposis autosomal carries causative congenital contracture deleterious export fatal fus global haploinsufficiency hela hgle1 horn lethal missense morphants motor neuron nonsense pore recessive rescue splice unable
Tagcloud (Intersection) ?		zebrafish