UXT and RUNX1

Number of citations of the paper that reports this interaction (PMID 17635584)
6

Data Source:
BioGRID (two hybrid)

		UXT	RUNX1
Gene Name		ubiquitously-expressed, prefoldin-like chaperone	runt-related transcription factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Cytoskeleton	Basement Membrane Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	Regulatory Region DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Calcium Ion Binding Protein Binding ATP Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity Repressing Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Microtubule Cytoskeleton Organization Transcription, DNA-templated Mitochondrion Transport Along Microtubule Centrosome Organization	Skeletal System Development In Utero Embryonic Development Liver Development Myeloid Progenitor Cell Differentiation Transcription, DNA-templated Central Nervous System Development Regulation Of Signal Transduction Hemopoiesis Myeloid Cell Differentiation Negative Regulation Of Granulocyte Differentiation Positive Regulation Of Granulocyte Differentiation Hair Follicle Morphogenesis Embryonic Hemopoiesis Positive Regulation Of Angiogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Behavioral Response To Pain Peripheral Nervous System Neuron Development Definitive Hemopoiesis Regulation Of Hair Follicle Cell Proliferation Hematopoietic Stem Cell Proliferation Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Progesterone Secretion
Pathways
Drugs
Diseases
GWAS			Esophageal cancer ( 21642993) Immune response to smallpox vaccine (IL-6) ( 22542470) Phospholipid levels (plasma) ( 21829377) Preeclampsia ( 23551011)
Protein-Protein Interactions		19 interactors: APP AR CECR2 GLE1 KRT31 KRT40 KRTAP10-7 KRTAP10-8 LRPPRC LSM1 NOTCH2NL PAK7 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL	46 interactors: AES AR CBFA2T2 CBFA2T3 CBFB CCND1 CCND2 CCND3 CDK1 CDK6 CEBPA CEBPB COPRS CTBP2 DNMT1 EFNA2 ELF2 ELF4 EP300 ETS1 FOS FOXP3 HDAC1 HDAC3 HIPK1 HIPK2 JUN KAT6A KAT6B MYOD1 NCOR1 NCOR2 PAX5 PRMT1 RBM14 SPEN STUB1 SUV39H1 TAZ TLE1 TLE2 UBE2L6 UXT VDR WWTR1 YAP1
Entrez ID		8409	861
HPRD ID		02209	01043
Ensembl ID		ENSG00000126756	ENSG00000159216
Uniprot IDs		Q9UBK9	Q01196
PDB IDs			1CMO 1CO1 1E50 1H9D 1LJM
Enriched GO Terms of Interacting Partners?		Cell Growth Single-organism Behavior Posttranscriptional Regulation Of Gene Expression Locomotory Behavior Behavior Neuron Apoptotic Process Learning Or Memory Negative Regulation Of Integrin Biosynthetic Process Developmental Process Neuron Death Cognition Synaptic Growth At Neuromuscular Junction Positive Regulation Of Progesterone Secretion Negative Regulation Of Mitochondrial RNA Catabolic Process Anatomical Structure Development Collateral Sprouting In Absence Of Injury Positive Regulation Of Integrin Biosynthetic Process Regulation Of Progesterone Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Hair Follicle Cell Proliferation Regulation Of Integrin Biosynthetic Process MRNA Transport Neuron Development Memory Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Steroid Hormone Microtubule-based Transport Programmed Cell Death Regulation Of Protein Stability Skeletal Muscle Tissue Development RNA Transport Learning Notch Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Skeletal Muscle Atrophy Growth Cytoskeleton-dependent Intracellular Transport Tissue Development Cell Death Death Skeletal Muscle Organ Development RNA Localization Axon Choice Point Recognition Striated Muscle Atrophy Response To Abiotic Stimulus	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Gene Expression RNA Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Organ Development Developmental Process System Development Regulation Of Cellular Process Cell Differentiation Multicellular Organismal Development Anatomical Structure Development Notch Signaling Pathway Chromatin Organization Cellular Metabolic Process Chromatin Modification Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of Cell Differentiation Response To Organic Substance
Tagcloud ?		angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel zebrafish	1q22 aml correlative cytogenetic decitabine demethylating elucidate epigenetics frequent haematological hypermethylation inactivation inv leukaemia leukaemias lymphocytic malignancies methylated mostly myelodysplatic p13 promoters re relapse runx2 runx3 syndromes unmethylated
Tagcloud (Difference) ?		angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel zebrafish	1q22 aml correlative cytogenetic decitabine demethylating elucidate epigenetics frequent haematological hypermethylation inactivation inv leukaemia leukaemias lymphocytic malignancies methylated mostly myelodysplatic p13 promoters re relapse runx2 runx3 syndromes unmethylated
Tagcloud (Intersection) ?