UXT and SVIL

Number of citations of the paper that reports this interaction (PMID 20309963)
11

Data Source:
BioGRID (two hybrid)

		UXT	SVIL
Gene Name		ubiquitously-expressed, prefoldin-like chaperone	supervillin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Cytoskeleton	Podosome Nucleus Cytoplasm Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere Invadopodium
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	Protein Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Microtubule Cytoskeleton Organization Transcription, DNA-templated Mitochondrion Transport Along Microtubule Centrosome Organization	Cytoskeleton Organization Skeletal Muscle Tissue Development Positive Regulation Of Cytokinesis
Pathways
Drugs
Diseases
GWAS			Normalized brain volume ( 19010793)
Protein-Protein Interactions		19 interactors: APP AR CECR2 GLE1 KRT31 KRT40 KRTAP10-7 KRTAP10-8 LRPPRC LSM1 NOTCH2NL PAK7 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL	37 interactors: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LIMA1 LMNA LMNB2 LUC7L2 MIF4GD MKL2 MPHOSPH9 NME2 NR3C1 ODF2 P2RX7 PAN3 PCNXL3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG
Entrez ID		8409	6840
HPRD ID		02209	04992
Ensembl ID		ENSG00000126756	ENSG00000197321
Uniprot IDs		Q9UBK9	O95425 Q569J5
PDB IDs			2K6M 2K6N
Enriched GO Terms of Interacting Partners?		Cell Growth Single-organism Behavior Posttranscriptional Regulation Of Gene Expression Locomotory Behavior Behavior Neuron Apoptotic Process Learning Or Memory Negative Regulation Of Integrin Biosynthetic Process Developmental Process Neuron Death Cognition Synaptic Growth At Neuromuscular Junction Positive Regulation Of Progesterone Secretion Negative Regulation Of Mitochondrial RNA Catabolic Process Anatomical Structure Development Collateral Sprouting In Absence Of Injury Positive Regulation Of Integrin Biosynthetic Process Regulation Of Progesterone Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Hair Follicle Cell Proliferation Regulation Of Integrin Biosynthetic Process MRNA Transport Neuron Development Memory Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Steroid Hormone Microtubule-based Transport Programmed Cell Death Regulation Of Protein Stability Skeletal Muscle Tissue Development RNA Transport Learning Notch Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Skeletal Muscle Atrophy Growth Cytoskeleton-dependent Intracellular Transport Tissue Development Cell Death Death Skeletal Muscle Organ Development RNA Localization Axon Choice Point Recognition Striated Muscle Atrophy Response To Abiotic Stimulus	Organelle Organization Regulation Of Cellular Component Organization Mitotic Cell Cycle Process Regulation Of Organelle Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Mitotic Nuclear Division Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Component Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Nitrogen Compound Metabolic Process Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Positive Regulation Of Gene Expression Establishment Of Organelle Localization Apoptotic Process Transcription, DNA-templated Programmed Cell Death Regulation Of Signaling Microtubule-based Process Steroid Hormone Mediated Signaling Pathway Developmental Process Cell Death Death Establishment Of Localization In Cell RNA Biosynthetic Process Metaphase Plate Congression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Positive Regulation Of Organelle Organization Transcription From RNA Polymerase II Promoter Response To Organic Substance G2/M Transition Of Mitotic Cell Cycle Organelle Localization Heterocycle Metabolic Process Establishment Of Protein Localization Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process
Tagcloud ?		angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel zebrafish	10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin
Tagcloud (Difference) ?		angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel zebrafish	10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin
Tagcloud (Intersection) ?