UXT and MPP1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		UXT	MPP1
Name		ubiquitously expressed prefoldin like chaperone	MAGUK p55 scaffold protein 1
Structure		No pdb structure
GO Annotations	Cellular Component	Chromatin Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton Mediator Complex Protein-containing Complex Protein Folding Chaperone Complex RPAP3/R2TP/prefoldin-like Complex	Cytoskeleton Plasma Membrane Cell-cell Junction Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite Cell Projection
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	GMP Kinase Activity Signaling Receptor Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule Protein Stabilization	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis
Pathways		Transcriptional Regulation by E2F6	Sensory processing of sound by outer hair cells of the cochlea
GWAS		No GWAS studies recorded	Hematology traits ( 23263863 ) Mean corpuscular volume ( 23263863 ) Red blood cell traits ( 23446634 )
Interacting Genes		29 interacting genes: APP AR CECR2 DYNLT1 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 TXNIP VHL	46 interacting genes: ABCC4 ACER1 ACER2 AGPAT3 AMOTL2 AP2M1 APH1A ATP5F1C ATRAID DERL2 DGAT2L6 DLG4 DNPEP ERBIN FXR2 GADD45A GPRASP3 GSK3B GYPC HNRNPD INCA1 KLHL12 MAP3K20 MEOX2 NR1H2 OGT OPTN PAQR8 PRIMPOL RPRM RPS6KA1 RPS6KA6 SGSM2 SLC35E1 SMN1 SRSF10 STK3 STUB1 SYNGR3 TK1 TMEM239 TRIM55 TRIM63 USP21 UXT ZNF639
Entrez ID		8409	4354
HPRD ID		02209	02370
Ensembl ID		ENSG00000126756	ENSG00000130830
Uniprot IDs		Q9UBK9	B4E325 Q00013
PDB IDs		Not available	2EJY 2EV8 3NEY
GO Terms Enriched among Interactors		Intermediate Filament Keratin Filament Amyloid Fibril Formation Identical Protein Binding Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis	Intracellular Signal Transduction TOR Signaling Ribosomal Protein S6 Kinase Activity N-acylsphingosine Amidohydrolase Activity