ATP13A1 and APPBP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP13A1	APPBP2
Description		ATPase 13A1	amyloid beta precursor protein binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Microtubule Microtubule Associated Complex Membrane Cytoplasmic Vesicle Membrane Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding ABC-type Manganese Transporter Activity P-type Ion Transporter Activity ATP Hydrolysis Activity ATPase-coupled Monoatomic Cation Transmembrane Transporter Activity Metal Ion Binding P-type Transmembrane Transporter Activity Membrane Protein Dislocase Activity	Microtubule Motor Activity Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Intracellular Calcium Ion Homeostasis Protein Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Manganese Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport Extraction Of Mislocalized Protein From ER Membrane	Intracellular Protein Transport Protein Transport Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intracellular Transport
Pathways		Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Refractive error ( 32231278) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Serum alkaline phosphatase levels ( 33339817) Toenail selenium levels ( 25343990) White blood cell count ( 32888494)	Interleukin-6 levels ( 33517400) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Waist-hip ratio ( 28552196)
Interacting Genes		37 interacting genes: AGTR1 APPBP2 AQP6 ARHGEF5 BIK BUD31 CBARP CXCR2 CYB5R3 EBP ELOVL4 ERGIC3 FAM209A FFAR2 GLP1R GPR42 KMT2E MANBAL MMD RNASEK RUNX1 SCN3B SLC10A1 SLC10A6 SLC16A13 SLC30A2 SLC30A8 SLC35H1 SLC71A2 SNCA SYPL2 TLCD4 TMBIM6 TMEM14B TMEM237 UNC93A VMA21	122 interacting genes: - AADAC ACTN1 AHCY AIM2 AK3 ALDH1L1 ANKRD10 APP AR ARMCX5 ASCC3 ATP13A1 BCL7A BIN2 C1orf50 CALM3 CCDC167 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CST2 CTC1 CYBA DCD DHRS2 DHX16 DOLK DPEP1 DPYS EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GPRC5C GSTP1 H2AC15 HGFAC HIPK4 HSD3B7 HSPA4 ITGB4 ITGB5 KHK KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MAN2B2 MCOLN1 MGAT4B MLLT3 MMP28 MRPL28 MSH2 MSLN MUL1 MYLK NFYA NHERF1 NPRL3 PCSK5 PEX39 PI4KAP2 PNPLA5 PPIL6 PPP1R8 PRKAA2 PRKACB PSAP PTCH1 PYROXD2 RAB7B RASSF5 RHEB RILPL1 RNF128 RNF34 RNGTT RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SLC33A2 SLC7A10 SNX5 SPDYE2 SPDYE2B ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 TNP2 TRMT2A UBE2R2 UGGT2 WAS WDR24 WFIKKN1 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		57130	10513
HPRD ID		12501	05616
Ensembl ID		ENSG00000105726	ENSG00000062725
Uniprot IDs		Q9HD20	Q92624
PDB IDs			8JAL 8JAQ 8JAR 8JAS 8JAU 8JAV
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Chemical Homeostasis Bile Acid:sodium Symporter Activity Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Zinc:proton Antiporter Activity Protein Binding Intracellular Monoatomic Cation Homeostasis Zinc Ion Import Into Organelle Intracellular Monoatomic Ion Homeostasis Plasma Membrane Homeostatic Process	Protein Binding
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