ATP13A1 and GPR42

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP13A1	GPR42
Description		ATPase 13A1	G protein-coupled receptor 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding ABC-type Manganese Transporter Activity P-type Ion Transporter Activity ATP Hydrolysis Activity ATPase-coupled Monoatomic Cation Transmembrane Transporter Activity Metal Ion Binding P-type Transmembrane Transporter Activity Membrane Protein Dislocase Activity	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Protein Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Manganese Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport Extraction Of Mislocalized Protein From ER Membrane	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Refractive error ( 32231278) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Serum alkaline phosphatase levels ( 33339817) Toenail selenium levels ( 25343990) White blood cell count ( 32888494)
Interacting Genes		37 interacting genes: AGTR1 APPBP2 AQP6 ARHGEF5 BIK BUD31 CBARP CXCR2 CYB5R3 EBP ELOVL4 ERGIC3 FAM209A FFAR2 GLP1R GPR42 KMT2E MANBAL MMD RNASEK RUNX1 SCN3B SLC10A1 SLC10A6 SLC16A13 SLC30A2 SLC30A8 SLC35H1 SLC71A2 SNCA SYPL2 TLCD4 TMBIM6 TMEM14B TMEM237 UNC93A VMA21	110 interacting genes: ADGRE2 ADIPOQ ALOX5AP ANKRD46 APOD ATP13A1 ATP4B ATP6V0B ATP6V0C BNIP3 BTN2A2 C1GALT1 CATSPERH CCDC167 CCL4L2 CD300C CD79A CLCA4 CLEC2D CMTM5 COMT CTXN3 CXCL16 CXCL9 DRAM1 EFNA5 EMP1 ERG28 ERMP1 FAM3C FXYD3 FXYD6 GIMAP5 GJB2 GOSR2 GPR37L1 GYPC IER3IP1 IGFBP5 IL1RL1 ITGAM JPH1 KCNA1 KLRG1 LAT LEPROTL1 LHFPL5 LNPEP LTC4S MFSD6 MGAM MS4A1 MS4A13 NDUFB11 NINJ2 NRM NSG1 PAEP PLP1 PLPP1 PMP22 PNLIPRP1 RPRM RTP2 RUSF1 SCD SERINC1 SERP2 SERTM1 SLC30A2 SLC30A3 SLC30A8 SLC35E4 SLC38A1 SLC38A7 SLC39A2 SLC41A1 SLC41A2 SLC61A1 SMCO4 SMIM3 STATH STRIT1 STX8 SYNDIG1 SYNGR1 TEX264 TF TM4SF4 TMBIM6 TMEM128 TMEM140 TMEM147 TMEM182 TMEM19 TMEM237 TMEM239 TMEM242 TMEM30B TMEM60 TMEM65 TRARG1 TREX1 TSPO2 YIF1A YIPF1 YIPF2 YIPF4 YIPF6 ZFPL1
Entrez ID		57130	2866
HPRD ID		12501	16033
Ensembl ID		ENSG00000105726	ENSG00000126251
Uniprot IDs		Q9HD20	A0A0K0PUY3 O15529
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Chemical Homeostasis Bile Acid:sodium Symporter Activity Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Zinc:proton Antiporter Activity Protein Binding Intracellular Monoatomic Cation Homeostasis Zinc Ion Import Into Organelle Intracellular Monoatomic Ion Homeostasis Plasma Membrane Homeostatic Process	Membrane Plasma Membrane Monoatomic Ion Transport Monoatomic Cation Transmembrane Transporter Activity Protein Binding Metal Ion Transport Monoatomic Cation Transport Endoplasmic Reticulum Inorganic Ion Transmembrane Transport Transmembrane Transport Endoplasmic Reticulum Membrane Monoatomic Ion Transmembrane Transport Inorganic Cation Transmembrane Transport Monoatomic Cation Transmembrane Transport Zinc Ion Transmembrane Transporter Activity Golgi Trans Cisterna Zinc Ion Transmembrane Transport Golgi Medial Cisterna Zinc Ion Transport Zinc Ion Import Into Organelle Monoatomic Cation Homeostasis Zinc Ion Import Into Lysosome Intracellular Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Intracellular Monoatomic Ion Homeostasis Leukotriene-C4 Synthase Activity Chemical Homeostasis Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Zinc:proton Antiporter Activity Cellular Response To Magnesium Ion
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