GOPC and GEM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GOPC	GEM
Description		golgi associated PDZ and coiled-coil motif containing	GTP binding protein overexpressed in skeletal muscle
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Trans-Golgi Network Transport Vesicle Dendrite Golgi-associated Vesicle Membrane Protein-containing Complex Cell Projection Synapse	Nucleus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Midbody Spindle Midzone Mitotic Spindle
	Molecular Function	Protein Binding Identical Protein Binding Transmembrane Transporter Binding Molecular Sequestering Activity	Nucleotide Binding Magnesium Ion Binding GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Negative Regulation Of Anion Channel Activity Protein Transport Apical Protein Localization Negative Regulation Of Protein Localization To Cell Surface	Mitotic Cell Cycle Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Chromosome Organization Metaphase Chromosome Alignment
Pathways		RHO GTPases regulate CFTR trafficking RHOQ GTPase cycle	NPAS4 regulates expression of target genes
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Colorectal cancer ( 23266556) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial emotion recognition (fearful faces) ( 28608620) Mild obesity-related type 2 diabetes ( 34737425) Night sleep phenotypes ( 27126917)	Carotid plaque burden ( 28282560) Coronary artery disease ( 29212778 33020668) Pulse pressure ( 30578418)
Interacting Genes		71 interacting genes: ABCA1 ADRB1 AKIRIN1 ASIC3 BATF BECN1 C17orf67 CCDC102B CCDC198 CD300C CDKN2C CEBPA CERCAM CFTR CLCN3 CRHR1 CSPG5 DLEU1 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GEM GOLGA3 GRID1 GRID2 HCK HNRNPLL IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MYLK MYOCD NOTCH1 NUP62 OSBP2 PARK7 PID1 PPP1R18 PWWP3A RALGAPB RELA RHOQ RNF183 RNF220 RPL13AP17 RPS6KA1 RTKN SEMA4G SLC25A18 SNX31 SPATA8 SSTR5 STARD3 STX6 TGFBR2 UBE3A VIM VTN ZBTB49 ZDHHC1 ZNF564 ZNF581 ZNF587 ZNF835 ZSCAN1	128 interacting genes: A2M AHCYL1 ANKRD36B APOH ASB15 BEGAIN BLOC1S2 BLZF1 BMP1 CACNB3 CALM1 CARD9 CCDC102B CCDC125 CCDC88B CDR2 CEP70 CLDN15 CLEC4G COG6 COG8 CTSL CYSRT1 DBF4B DEUP1 DISC1 DRC4 ECSIT EFHC2 EXOSC8 FSAF1 GADD45GIP1 GMIP GOLGA2 GOLGA6L9 GOPC GPRASP3 HOOK2 HSF2BP IHO1 IKZF3 INCA1 INO80E INSC ISCA2 KATNBL1 KCTD9 KIFC3 KLC3 KRT31 KRT34 KRT36 KRT40 KRT6A KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-8 LIMS1 LRP2BP LZTS2 MCRS1 MESD MGLL MID2 MIPOL1 MKRN3 MORN3 MSS51 MTUS2 MYOG NDUFAF3 NDUFB7 NDUFS8 NOTCH2NLA OIP5 PBX4 PDLIM7 PIH1D1 PLAGL2 PLEKHF2 PNMA1 POF1B PRDM14 PRDM6 RNF7 RUNDC3A SDHB SNAP91 SORBS3 SPAG5 SPATA6 SSX2IP TBC1D3B TBC1D3G TCF4 TFIP11 TGM7 TLE5 TP53BP2 TRAF1 TRAF2 TRIM10 TRIM23 TRIM27 TRIM32 TRIM54 TRIM69 USH1G USHBP1 VIM VPS28 VPS52 VTN WWOX YBEY YPEL3 YWHAB ZBTB42 ZC4H2 ZMAT5 ZNF20 ZNF552 ZNF655 ZNF688 ZNF774 ZRANB1 ZSCAN9
Entrez ID		57120	2669
HPRD ID		06024	11553
Ensembl ID		ENSG00000047932	ENSG00000164949
Uniprot IDs		Q9HD26	P55040
PDB IDs		2DC2 2LOB 4E34 4E35 4JOE 4JOF 4JOG 4JOH 4JOJ 4JOK 4JOP 4JOR 4K6Y 4K72 4K75 4K76 4K78 4NMO 4NMP 4NMQ 4NMR 4NMS 4NMT 4NMV 4Q6H 4Q6S 5IC3 5K4F 6OV7 6V84 6XNJ 7JZO 7JZP 7JZQ 7JZR	2CJW 2G3Y 2HT6
Enriched GO Terms of Interacting Partners?		Response To Lipid Phagocytic Vesicle PDZ Domain Binding Golgi-associated Vesicle Membrane Response To Xenobiotic Stimulus Positive Regulation Of Cellular Component Biogenesis Phagocytosis, Engulfment Response To Vitamin Negative Regulation Of Cell Population Proliferation Regeneration Liver Development Response To Hormone Positive Regulation Of Transcription By RNA Polymerase II Response To Steroid Hormone Positive Regulation Of Reactive Oxygen Species Metabolic Process Glutamatergic Synapse Transcription Factor AP-1 Complex Trans-synaptic Protein Complex AMPA Glutamate Receptor Activity Scaffold Protein Binding SMAD Protein Signal Transduction Postsynapse To Nucleus Signaling Pathway Response To Muramyl Dipeptide Membrane Hyperpolarization Negative Regulation Of Skeletal Muscle Cell Differentiation Myeloid Leukocyte Differentiation Hormone-mediated Signaling Pathway Cell Surface Receptor Signaling Pathway Mononuclear Cell Differentiation Regulation Of Stem Cell Proliferation Signal Transduction Organic Hydroxy Compound Transport Integrated Stress Response Signaling Synaptic Signaling Via Neuropeptide Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Negative Regulation Of Cell Adhesion Molecule Production	Identical Protein Binding Protein Binding Keratin Filament Intermediate Filament Cytoskeleton Intermediate Filament Organization Microtubule Binding Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Microtubule Cytoskeleton Organization Zinc Ion Binding Organelle Organization TORC1 Complex Assembly Centrosome Negative Regulation Of Viral Transcription Suppression Of Viral Release By Host Microtubule-based Process Supramolecular Fiber Organization Ubiquitin Protein Ligase Activity Regulation Of Viral Transcription Protein Localization To Cytoskeleton
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