GOPC and RHOQ

Number of citations of the paper that reports this interaction (PMID 11162552)
13

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		GOPC	RHOQ
Gene Name		golgi-associated PDZ and coiled-coil motif containing	ras homolog family member Q
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Cell Junction Trans-Golgi Network Transport Vesicle Dendrite Protein Complex Postsynaptic Membrane	Cytosol Actin Filament Plasma Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Small GTPase Regulator Activity Frizzled Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity Ion Channel Binding	GTPase Activity Profilin Binding GTP Binding GBD Domain Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Spermatid Nucleus Differentiation Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Regulation Of Catalytic Activity Protein Homooligomerization	Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Pathways			Rho GTPase cycle Signaling by Rho GTPases Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS		Colorectal cancer ( 23266556)
Protein-Protein Interactions		58 interactors: ABCA1 ADRB1 AKIRIN1 ASIC3 BATF BECN1 C17orf67 CCDC102B CD300C CDC42 CDKN2C CERCAM CFTR CLCN3 CSPG5 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GOLGA3 GRID1 GRID2 HCK IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MUM1 MYLK MYOCD NUP62 PARK7 PID1 RELA RHOQ RNF183 RNF220 RPL13AP17 RTKN SEMA4G SLC25A18 SPATA8 SSNA1 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZNF564 ZNF581 ZNF587 ZSCAN1	18 interactors: CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL
Entrez ID		57120	23433
HPRD ID		06024	05791
Ensembl ID		ENSG00000047932
Uniprot IDs		Q9HD26	P17081
PDB IDs		2DC2 2LOB 4E34 4E35	2ATX
Enriched GO Terms of Interacting Partners?		Cellular Response To Stimulus Cellular Response To Organic Substance Response To External Stimulus Myeloid Leukocyte Differentiation Leukocyte Differentiation Response To Organic Substance Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Phosphorylation Response To Stimulus Cellular Process Cell Communication Positive Regulation Of Cellular Biosynthetic Process Regulation Of Binding Positive Regulation Of Transport Regulation Of Cellular Process Cell Differentiation Regulation Of Membrane Potential Myeloid Dendritic Cell Differentiation Cellular Response To Hormone Stimulus Signal Transduction Blood Vessel Morphogenesis Myeloid Dendritic Cell Activation Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of DNA Binding Response To Extracellular Stimulus Negative Regulation Of Protein Phosphorylation Cell Death Death Positive Regulation Of Gene Expression T-helper 17 Cell Lineage Commitment Response To Lipid Regulation Of Phosphorylation Cellular Localization Membrane Hyperpolarization Negative Regulation Of Cell Proliferation Defense Response Regulation Of Signaling Response To Drug Positive Regulation Of DNA Binding Blood Vessel Development Response To Mechanical Stimulus Response To Stress Signaling Response To Cytokine T-helper 17 Cell Differentiation Dendritic Cell Differentiation Response To Other Organism	Positive Regulation Of Cell Projection Organization Positive Regulation Of Pseudopodium Assembly Regulation Of Cell Projection Assembly Regulation Of Cell Projection Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Cellular Component Biogenesis Golgi Vesicle Budding Positive Regulation Of Protein Complex Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Membrane Budding Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Regulation Of Cytoskeleton Organization Regulation Of Catalytic Activity Intracellular Signal Transduction Regulation Of Cellular Component Size Actin Cytoskeleton Organization Regulation Of Cellular Component Organization Regulation Of Protein Complex Assembly Small GTPase Mediated Signal Transduction Localization Within Membrane Vesicle-mediated Transport Actin Filament-based Process Positive Regulation Of Hydrolase Activity Regulation Of Cell Shape Tight Junction Assembly Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Ras GTPase Activity Cell Junction Assembly Regulation Of GTPase Activity Vesicle Organization Cell-cell Junction Organization Ras Protein Signal Transduction Apical Junction Assembly Organelle Organization Positive Regulation Of Rho GTPase Activity COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Regulation Of Organelle Organization Regulation Of Ras GTPase Activity Golgi Vesicle Transport Regulation Of Rho GTPase Activity Positive Regulation Of Catalytic Activity
Tagcloud ?		admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits
Tagcloud (Difference) ?		admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits
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