GOPC and CSPG5

Number of citations of the paper that reports this interaction (PubMedID 12885772)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, two hybrid)

		GOPC	CSPG5
Description		golgi associated PDZ and coiled-coil motif containing	chondroitin sulfate proteoglycan 5
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Trans-Golgi Network Transport Vesicle Dendrite Golgi-associated Vesicle Membrane Protein-containing Complex Cell Projection Synapse	Golgi Membrane Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Lumen Plasma Membrane Cell Surface Membrane Golgi-associated Vesicle Membrane Lysosomal Lumen Synapse Postsynaptic Membrane Synaptic Membrane Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Binding Identical Protein Binding Transmembrane Transporter Binding Molecular Sequestering Activity	Protein Binding Growth Factor Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Negative Regulation Of Anion Channel Activity Protein Transport Apical Protein Localization Negative Regulation Of Protein Localization To Cell Surface	Cytoskeleton Organization Signal Transduction Nervous System Development Cell Differentiation Intracellular Transport Cell Projection Morphogenesis Modulation Of Chemical Synaptic Transmission Glial Cell Projection Elongation Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Synaptic Vesicle Exocytosis
Pathways		RHO GTPases regulate CFTR trafficking RHOQ GTPase cycle	Glycosaminoglycan-protein linkage region biosynthesis CS-GAG biosynthesis DS-GAG biosynthesis CS/DS degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective CHST14 causes EDS, musculocontractural type Defective CHSY1 causes TPBS Defective B3GALT6 causes EDSP2 and SEMDJL1
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Colorectal cancer ( 23266556) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial emotion recognition (fearful faces) ( 28608620) Mild obesity-related type 2 diabetes ( 34737425) Night sleep phenotypes ( 27126917)	Body mass index ( 29273807) Smoking initiation ( 33082346)
Interacting Genes		71 interacting genes: ABCA1 ADRB1 AKIRIN1 ASIC3 BATF BECN1 C17orf67 CCDC102B CCDC198 CD300C CDKN2C CEBPA CERCAM CFTR CLCN3 CRHR1 CSPG5 DLEU1 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GEM GOLGA3 GRID1 GRID2 HCK HNRNPLL IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MYLK MYOCD NOTCH1 NUP62 OSBP2 PARK7 PID1 PPP1R18 PWWP3A RALGAPB RELA RHOQ RNF183 RNF220 RPL13AP17 RPS6KA1 RTKN SEMA4G SLC25A18 SNX31 SPATA8 SSTR5 STARD3 STX6 TGFBR2 UBE3A VIM VTN ZBTB49 ZDHHC1 ZNF564 ZNF581 ZNF587 ZNF835 ZSCAN1	3 interacting genes: CTSA ERBB3 GOPC
Entrez ID		57120	10675
HPRD ID		06024	08423
Ensembl ID		ENSG00000047932	ENSG00000114646
Uniprot IDs		Q9HD26	A0A087WUT8 B7Z2E0 O95196
PDB IDs		2DC2 2LOB 4E34 4E35 4JOE 4JOF 4JOG 4JOH 4JOJ 4JOK 4JOP 4JOR 4K6Y 4K72 4K75 4K76 4K78 4NMO 4NMP 4NMQ 4NMR 4NMS 4NMT 4NMV 4Q6H 4Q6S 5IC3 5K4F 6OV7 6V84 6XNJ 7JZO 7JZP 7JZQ 7JZR
Enriched GO Terms of Interacting Partners?		Response To Lipid Phagocytic Vesicle PDZ Domain Binding Golgi-associated Vesicle Membrane Response To Xenobiotic Stimulus Positive Regulation Of Cellular Component Biogenesis Phagocytosis, Engulfment Response To Vitamin Negative Regulation Of Cell Population Proliferation Regeneration Liver Development Response To Hormone Positive Regulation Of Transcription By RNA Polymerase II Response To Steroid Hormone Positive Regulation Of Reactive Oxygen Species Metabolic Process Glutamatergic Synapse Transcription Factor AP-1 Complex Trans-synaptic Protein Complex AMPA Glutamate Receptor Activity Scaffold Protein Binding SMAD Protein Signal Transduction Postsynapse To Nucleus Signaling Pathway Response To Muramyl Dipeptide Membrane Hyperpolarization Negative Regulation Of Skeletal Muscle Cell Differentiation Myeloid Leukocyte Differentiation Hormone-mediated Signaling Pathway Cell Surface Receptor Signaling Pathway Mononuclear Cell Differentiation Regulation Of Stem Cell Proliferation Signal Transduction Organic Hydroxy Compound Transport Integrated Stress Response Signaling Synaptic Signaling Via Neuropeptide Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Negative Regulation Of Cell Adhesion Molecule Production	Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Neuregulin Receptor Activity Negative Regulation Of Chaperone-mediated Autophagy Lumenal Side Of Lysosomal Membrane Negative Regulation Of Anion Channel Activity ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Serine-type Carboxypeptidase Activity Schwann Cell Differentiation ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Transport Negative Regulation Of Motor Neuron Apoptotic Process Regulation Of Motor Neuron Apoptotic Process Motor Neuron Apoptotic Process Endocardial Cushion Development Negative Regulation Of Protein Localization To Cell Surface Regulation Of Monoatomic Anion Transport Golgi-associated Vesicle Membrane Apical Protein Localization Protein Tyrosine Kinase Activator Activity Molecular Sequestering Activity Trans-Golgi Network Transport Vesicle Schwann Cell Development Positive Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Striated Muscle Tissue Development ERBB2 Signaling Pathway Peripheral Nervous System Development Negative Regulation Of Transporter Activity Carboxypeptidase Activity Cranial Nerve Development Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Protein Localization To Cell Surface Regulation Of Striated Muscle Tissue Development Growth Factor Binding Regulation Of Muscle Organ Development Nerve Development Positive Regulation Of Calcium-mediated Signaling Mesenchyme Development Golgi To Plasma Membrane Transport Glial Cell Development Epidermal Growth Factor Receptor Signaling Pathway Protein Transport Basal Plasma Membrane Lateral Plasma Membrane
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