GOPC and ASIC3

Number of citations of the paper that reports this interaction (PMID 15317815)
21

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid, in vivo)

		GOPC	ASIC3
Gene Name		golgi-associated PDZ and coiled-coil motif containing	acid sensing (proton gated) ion channel 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Cell Junction Trans-Golgi Network Transport Vesicle Dendrite Protein Complex Postsynaptic Membrane	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Small GTPase Regulator Activity Frizzled Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity Ion Channel Binding	Cation Channel Activity Sodium Channel Activity Ligand-gated Sodium Channel Activity PDZ Domain Binding Enterobactin Transporter Activity
	Biological Process	ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Spermatid Nucleus Differentiation Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Regulation Of Catalytic Activity Protein Homooligomerization	Transport Signal Transduction Sensory Perception Response To Heat Response To Acidic PH Ion Transmembrane Transport Sodium Ion Transmembrane Transport Enterobactin Transport Sensory Perception Of Sour Taste Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Transmembrane Transport Cation Transmembrane Transport
Pathways			Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS		Colorectal cancer ( 23266556)
Protein-Protein Interactions		58 interactors: ABCA1 ADRB1 AKIRIN1 ASIC3 BATF BECN1 C17orf67 CCDC102B CD300C CDC42 CDKN2C CERCAM CFTR CLCN3 CSPG5 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GOLGA3 GRID1 GRID2 HCK IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MUM1 MYLK MYOCD NUP62 PARK7 PID1 RELA RHOQ RNF183 RNF220 RPL13AP17 RTKN SEMA4G SLC25A18 SPATA8 SSNA1 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZNF564 ZNF581 ZNF587 ZSCAN1	9 interactors: ASIC2 CSNK2A1 DLG4 GOPC INADL LIN7B MAGI1 PRKACA STOM
Entrez ID		57120	9311
HPRD ID		06024	10626
Ensembl ID		ENSG00000047932	ENSG00000213199
Uniprot IDs		Q9HD26	Q9UHC3
PDB IDs		2DC2 2LOB 4E34 4E35
Enriched GO Terms of Interacting Partners?		Cellular Response To Stimulus Cellular Response To Organic Substance Response To External Stimulus Myeloid Leukocyte Differentiation Leukocyte Differentiation Response To Organic Substance Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Phosphorylation Response To Stimulus Cellular Process Cell Communication Positive Regulation Of Cellular Biosynthetic Process Regulation Of Binding Positive Regulation Of Transport Regulation Of Cellular Process Cell Differentiation Regulation Of Membrane Potential Myeloid Dendritic Cell Differentiation Cellular Response To Hormone Stimulus Signal Transduction Blood Vessel Morphogenesis Myeloid Dendritic Cell Activation Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of DNA Binding Response To Extracellular Stimulus Negative Regulation Of Protein Phosphorylation Cell Death Death Positive Regulation Of Gene Expression T-helper 17 Cell Lineage Commitment Response To Lipid Regulation Of Phosphorylation Cellular Localization Membrane Hyperpolarization Negative Regulation Of Cell Proliferation Defense Response Regulation Of Signaling Response To Drug Positive Regulation Of DNA Binding Blood Vessel Development Response To Mechanical Stimulus Response To Stress Signaling Response To Cytokine T-helper 17 Cell Differentiation Dendritic Cell Differentiation Response To Other Organism	Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Ion Transport Maintenance Of Apical/basal Cell Polarity Regulation Of Cation Channel Activity Maintenance Of Cell Polarity Regulation Of Ion Transmembrane Transport Cellular Component Assembly Protein Localization To Synapse Asymmetric Protein Localization Establishment Or Maintenance Of Apical/basal Cell Polarity Golgi To Plasma Membrane Transport Cell-cell Signaling Regulation Of Sodium Ion Transport Regulation Of Cellular Component Organization Negative Regulation Of Transport Protein Complex Assembly Regulation Of Systemic Arterial Blood Pressure By Aortic Arch Baroreceptor Feedback Positive Regulation Of Dense Core Granule Biogenesis Cytoplasmic Sequestering Of CFTR Protein Regulation Of Acid-sensing Ion Channel Activity Post-Golgi Vesicle-mediated Transport Phototransduction Regulation Of Blood Coagulation Detection Of Light Stimulus Histone H3-T6 Phosphorylation Cell-cell Junction Assembly Nucleus Organization Signaling Regulation Of Wound Healing Cell Communication Synaptic Transmission Chemotaxis Spermatid Development Spermatid Differentiation Negative Regulation Of MAPK Cascade Protein Localization To Basolateral Plasma Membrane Sensory Perception Of Sour Taste Detection Of Abiotic Stimulus Cytosolic Calcium Ion Homeostasis Establishment Or Maintenance Of Cell Polarity Regulation Of Behavior Positive Regulation Of Transport Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Grooming Behavior Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of ERK1 And ERK2 Cascade Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Ion Transport
Tagcloud ?		admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits	amiloride asic1 asic1a asic2a asics blocker currents cyclooxygenase defense elusive exact existed existence glia homomeric lipopolysaccharide meanwhile microglia microglial neuroinflammatory nonspecific participate pctx1 qpcr scavenger scrape sensing transcriptase
Tagcloud (Difference) ?		admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits	amiloride asic1 asic1a asic2a asics blocker currents cyclooxygenase defense elusive exact existed existence glia homomeric lipopolysaccharide meanwhile microglia microglial neuroinflammatory nonspecific participate pctx1 qpcr scavenger scrape sensing transcriptase
Tagcloud (Intersection) ?