CCNL1 and APPBP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CCNL1	APPBP2
Gene Name		cyclin L1	amyloid beta precursor protein (cytoplasmic tail) binding protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Speck	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Kinase Binding	Microtubule Motor Activity Protein Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing	Intracellular Protein Transport Metabolic Process Intracellular Transport
Pathways
Drugs
Diseases
GWAS		Adiposity in newborns ( 23575227) Birth weight ( 23202124 20372150) Diabetic retinopathy ( 21441570) Eating disorders ( 22911880)
Protein-Protein Interactions		6 interactors: APP APPBP2 CDK11A JMJD6 SRSF2 TFIP11	79 interactors: AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 DCD DHRS2 DPEP1 EID3 EPT1 ERO1L FAM19A4 FAM92A1 FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 HIPK4 HIST1H2AK HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MGC34796 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		57018	10513
HPRD ID		10814	05616
Ensembl ID			ENSG00000062725
Uniprot IDs		C9JPL0 Q9UK58	Q92624
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing MRNA 3'-end Processing Regulation Of MRNA Processing Spliceosomal Complex Disassembly Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine RNA 3'-end Processing Cell Recognition Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Recognition Of Apoptotic Cell Regulation Of Nitrogen Compound Metabolic Process Neuron Remodeling RNA Metabolic Process Phagocytosis, Recognition Intracellular Transport Cellular Copper Ion Homeostasis Gene Expression Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle	Regulation Of Defense Response To Virus By Host Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homocysteine Metabolic Process Cellular Response To Organic Substance
Tagcloud ?		11q13 180k 3q25 alcohol cdkn2a clarified consumption corrected csmd1 cttn dcun1d1 exome fadd fhit hnscc hnsccs oncogenes oncosuppressors pik3ca preceding q qter scna scnas smoking tobacco tp53 tp63 trigger	10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?		11q13 180k 3q25 alcohol cdkn2a clarified consumption corrected csmd1 cttn dcun1d1 exome fadd fhit hnscc hnsccs oncogenes oncosuppressors pik3ca preceding q qter scna scnas smoking tobacco tp53 tp63 trigger	10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?