CCNL1 and RSRP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCNL1	RSRP1
Description		cyclin L1	arginine and serine rich protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Nuclear Speck	Nucleus
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of Cell Cycle	Spliceosomal Complex Assembly
Pathways
Drugs
Diseases
GWAS		Adiponectin levels in pregnancy ( 28317342) Adult body size ( 32376654) Alanine aminotransferase levels ( 33547301) Anthropometric traits in newborns ( 23575227) Birth weight ( 20372150 23202124 31453325 31043758 27680694) Birth weight variance ( 31453325) Body fat percentage variance ( 31453325) Body mass index ( 26426971) circulating leptin levels ( 32917775 26833098) circulating leptin levels adjusted for BMI ( 26833098 32917775) Coronary artery disease ( 33020668) Diabetic retinopathy ( 21441570) Eating disorders ( 22911880) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Menarche (age at onset) ( 25231870) Offspring birth weight ( 31043758) PR interval ( 32439900 30046033) Smoking cessation in chronic obstructive pulmonary disease ( 21685187)
Interacting Genes		21 interacting genes: APP APPBP2 C1orf35 CASP8 CDK11A DVL3 FAM133A JMJD6 KRTAP12-2 NKAPD1 PRDM6 PRPF40A RAD51D RNPS1 RSRP1 SORBS3 SREK1IP1 SRSF2 TFIP11 ZRANB1 ZRSR2	7 interacting genes: APP CCNL1 CLK2 CLK3 PRMT5 SRPK1 SRPK2
Entrez ID		57018	57035
HPRD ID		10814	14835
Ensembl ID		ENSG00000163660	ENSG00000117616
Uniprot IDs		Q9UK58	Q9BUV0
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process Regulation Of MRNA Processing RNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Nucleic Acid Binding	Regulation Of RNA Splicing Nuclear Speck Phosphorylation Protein Phosphorylation Protein Serine Kinase Activity Regulation Of MRNA Splicing, Via Spliceosome Protein Serine/threonine Kinase Activity Regulation Of MRNA Processing Protein Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein-RNA Complex Assembly Positive Regulation Of Viral Genome Replication Kinase Activity Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Nucleoplasm Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Amyloid-beta Complex Growth Cone Lamellipodium Chromatin Organization Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Nucleus Protein Modification Process Transferase Activity Regulation Of MRNA Metabolic Process Positive Regulation Of Viral Process Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Protein Metabolic Process Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Regulation Of Gene Expression Acetylcholine Receptor Activator Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Lipoprotein Particle Positive Regulation Of Protein Import Regulation Of Cell Cycle Peptidyl-arginine N-methylation PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization
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