RAD18 and TAX1BP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RAD18	TAX1BP1
Gene Name		RAD18 E3 ubiquitin protein ligase	Tax1 (human T-cell leukemia virus type I) binding protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromatin XY Body Nucleus Replication Fork	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Y-form DNA Binding Damaged DNA Binding Protein Binding Zinc Ion Binding Ligase Activity Polyubiquitin Binding Ubiquitin Protein Ligase Binding	Protein Binding Kinase Binding
	Biological Process	DNA Repair Spermatogenesis Response To UV Protein Ubiquitination Negative Regulation Of DNA Recombination	Apoptotic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process Innate Immune Response
Pathways			RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Negative regulators of RIG-I/MDA5 signaling Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: DZIP3 MAPK8 MLKL NBN PCGF6 PCNA POLK RAD51 RFC2 SHPRH SIVA1 TAX1BP1 TP53BP1 TRIM23 TRIM8 TSG101 UBC UBE2A UBE2B UBE2I USP2	40 interactors: ARHGAP1 CALCOCO2 CNTN2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN EMILIN1 FAM168A FAM189A2 FOXC2 GABARAP IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP1 TNIP3 TRAF6 TSG101 TSHZ3 UBC
Entrez ID		56852	8887
HPRD ID		09242	05618
Ensembl ID		ENSG00000070950	ENSG00000106052
Uniprot IDs		Q9NS91	A4D196 B4DSG5 Q86VP1
PDB IDs		2Y43 2YBF
Enriched GO Terms of Interacting Partners?		DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Stress Protein Ubiquitination Protein Modification By Small Protein Conjugation DNA Recombination Protein Polyubiquitination Nucleotide-excision Repair, DNA Gap Filling Response To Stress Postreplication Repair Cell Cycle Cell Cycle Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic Recombination Proteasomal Protein Catabolic Process Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Protein Catabolic Process Chromosome Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of RNA Biosynthetic Process Response To Radiation Viral Protein Processing Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Recombinational Repair Regulation Of Transcription, DNA-templated Cellular Macromolecule Catabolic Process Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Nucleotide-excision Repair Histone H2A Ubiquitination Negative Regulation Of Gene Expression DNA Replication Regulation Of RNA Metabolic Process Viral Process Negative Regulation Of Biosynthetic Process Response To Stimulus DNA-dependent DNA Replication Telomere Maintenance Via Semi-conservative Replication Programmed Cell Death Regulation Of Metabolic Process	Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling MyD88-independent Toll-like Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Organelle Disassembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Nucleophagy Immune Response-regulating Signaling Pathway JNK Cascade Cellular Response To Stress Mitochondrion Degradation Regulation Of Vascular Wound Healing Regulation Of Type I Interferon Production Stress-activated MAPK Cascade Negative Regulation Of Intracellular Signal Transduction Stress-activated Protein Kinase Signaling Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Autophagic Vacuole Assembly Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Activation Of MAPK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Macroautophagy Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Autophagy Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Protein Processing Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intracellular Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production Membrane Organization
Tagcloud ?		break camptothecin chemotherapeutic collaboratively conjugating doi dsb dsbs dt40 hypersensitivity joining ku70 ligases nhej nonhomologous olaparib onc operate poison polymerization promotion publication rad51 rays recombinase repaired rnf8 topoisomerase ubc13	100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Difference) ?		break camptothecin chemotherapeutic collaboratively conjugating doi dsb dsbs dt40 hypersensitivity joining ku70 ligases nhej nonhomologous olaparib onc operate poison polymerization promotion publication rad51 rays recombinase repaired rnf8 topoisomerase ubc13	100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Intersection) ?