TAX1BP1 and AZI2

Number of citations of the paper that reports this interaction (PubMedID 30459273)
38

Data Source:
BioGRID (x-ray crystallography, pull down, affinity chromatography technology)

		TAX1BP1	AZI2
Description		Tax1 binding protein 1	5-azacytidine induced 2
Image
GO Annotations	Cellular Component	Phagophore Assembly Site Cytoplasm Mitochondrion Autophagosome Cytosol Cytoplasmic Vesicle Extracellular Exosome	Cytoplasm Serine/threonine Protein Kinase Complex
	Molecular Function	Protein Binding Zinc Ion Binding Kinase Binding Protein-macromolecule Adaptor Activity Signaling Adaptor Activity Metal Ion Binding	Protein Binding
	Biological Process	Immune System Process Cytoplasmic Pattern Recognition Receptor Signaling Pathway Autophagy Apoptotic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Protein K48-linked Ubiquitination Protein Localization To Phagocytic Vesicle Negative Regulation Of Interleukin-1-mediated Signaling Pathway	Mitotic Cell Cycle T Cell Activation Negative Regulation Of Canonical NF-kappaB Signal Transduction Dendritic Cell Proliferation Defense Response To Virus Type I Interferon-mediated Signaling Pathway Dendritic Cell Differentiation
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)	Cognitive decline (age-related) ( 28078323)
Interacting Genes		72 interacting genes: ARHGAP1 ARK2N AZI2 CBX8 COG7 CWF19L2 CXXC1 DAXX DAZAP2 DSTN ENTREP1 FAM161A FAM168A FAM90A1 FOXC2 GABARAP GABARAPL1 GABARAPL2 IGFN1 IKBKG KANK2 KAT5 KIF5B L3MBTL2 LITAF LMO3 LNX1 LRATD2 MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 NTAQ1 ORC5 PIBF1 PLEKHB2 PLEKHN1 POLR1C RAB18 RAD18 RAD23B RAD54L2 RIPK1 RNF11 RNF26 SCNM1 SH3GLB1 SSX2 STARD13 TBC1D15 TBC1D17 TCAF1 TCEA2 TCL1A TNFAIP3 TNIP3 TRAF4 TRAF6 TRAPPC6A TRIM14 TRIM45 TSEN2 TSG101 TSHZ3 UBA52 UBASH3A UBB UBC UBTFL1 USP2 ZNF446	16 interacting genes: APBA3 FAM107A GABARAP GABARAPL1 GABARAPL2 IKBKE MIB1 MTPAP N4BP1 RB1CC1 RNF31 TAX1BP1 TBK1 TICAM1 TRAF3 TXLNA
Entrez ID		8887	64343
HPRD ID		05618	10577
Ensembl ID		ENSG00000106052	ENSG00000163512
Uniprot IDs		B4DSG5 Q86VP1	Q9H6S1
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G 8W6A 8W6B	5EP6 5Z7G 5Z7L 7EA2 7EA7
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Binding Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Protein Binding Autophagosome Autophagosome Maturation Protein-containing Complex Disassembly Autophagosome Membrane Cytoplasm Modification-dependent Protein Catabolic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Polyubiquitin Modification-dependent Protein Binding Macromolecule Catabolic Process Endosome Membrane Proteolysis Involved In Protein Catabolic Process Protein Tag Activity Autophagy GABA Receptor Binding Autophagosome Assembly Regulation Of Canonical NF-kappaB Signal Transduction Macroautophagy Autophagosome Organization Mitophagy Ubiquitin Protein Ligase Activity Cellular Response To Starvation WW Domain Binding Post-translational Protein Modification Protein Ubiquitination Autophagy Of Mitochondrion Catabolic Process Regulation Of Protein Modification Process Signaling Adaptor Activity Response To Starvation Protein Modification Process Proteolysis Ubiquitin-dependent Protein Catabolic Process Regulation Of Macromolecule Metabolic Process Protein Modification By Small Protein Conjugation Beta-tubulin Binding Regulation Of Primary Metabolic Process Cellular Response To Nutrient Levels Organelle Assembly Vacuole Organization Identical Protein Binding Zinc Ion Binding Cytosol Positive Regulation Of Protein Modification Process	Autophagosome Cell Surface Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Cellular Response To Nitrogen Starvation Ubiquitin Protein Ligase Binding Regulation Of Canonical NF-kappaB Signal Transduction Cell Surface Pattern Recognition Receptor Signaling Pathway Autophagy Autophagosome Membrane Macroautophagy Phosphatidylethanolamine Binding GABA Receptor Binding Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Cytoplasm Autophagy Of Mitochondrion Serine/threonine Protein Kinase Complex Activation Of Innate Immune Response Positive Regulation Of Type I Interferon Production Activation Of Immune Response Autophagosome Assembly Regulation Of Innate Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Defense Response Autophagosome Organization Response To Other Organism Cellular Response To Nutrient Levels Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Defense Response Defense Response To Virus Regulation Of Type I Interferon Production Positive Regulation Of Innate Immune Response Beta-tubulin Binding Response To External Biotic Stimulus Defense Response Regulation Of Immune Response Immune System Process Response To Stress Immune Response-activating Signaling Pathway Autophagosome Maturation Pattern Recognition Receptor Signaling Pathway Type I Interferon-mediated Signaling Pathway Innate Immune Response Vacuole Organization Positive Regulation Of Autophagy Positive Regulation Of Immune Response Innate Immune Response-activating Signaling Pathway Cell Surface Receptor Signaling Pathway Mitophagy Regulation Of Interferon-beta Production Response To Virus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?